Results 21 to 30 of about 2,314,582 (300)
BMC Cancer, 2014 BackgroundTherapeutic decisions in cancer are generally guided by molecular biomarkers or, for some newer therapeutics, primary tumor genotype. However, because biomarkers or genotypes may change as new metastases emerge, circulating tumor cells (CTCs ...
Glenn Deng +7 more
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Frontiers in Immunology, 2021 Cancer-associated fibroblasts (CAFs) has been recognized as one cause of tumor resistance to immune checkpoint blockade therapy, but the underlying mechanisms still remain elusive.
Tinglei Huang +9 more
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Theranostics, 2020 Cancer is the second leading cause of death worldwide and patients are in urgent need of therapies that can effectively target cancer with minimal off-target side effects.
Li Qiao +12 more
semanticscholar +1 more source
Effect of IL-10-producing B cells in peripheral blood and tumor tissue on gastric cancer
Cell Communication and Signaling, 2023 Background Interleukin (IL)-10-producing B (B10) cells are generated in response to signals from the tumor microenvironment and promote tumor growth by interacting with B10 cells.
Yoon Ju Jung +9 more
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Frontiers in Oncology, 2022 BackgroundEvidence has shown neurons and glial cells were closely related to tumor progression. As the predominant glial cells in the external innervated nerves of the gastrointestinal, the role of Schwann cells (SCs) in colorectal cancer (CRC) has not ...
Shuhai Chen, Mingyou Chen
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Macrophage induces anti-cancer drug resistance in canine mammary gland tumor spheroid
Scientific Reports, 2023 Tumor-associated macrophages (TAMs) play an important role in the tumor microenvironment by producing cytokines and growth factors. Furthermore, TAMs play multifunctional roles in tumor progression, immune regulation, metastasis, angiogenesis, and ...
Ga-Hyun Lim +6 more
doaj +1 more source
Human macrophage-engineered vesicles for utilization in ovarian cancer treatment
Frontiers in Oncology, 2023 BackgroundOvarian cancer is a deadly female malignancy with a high rate of recurrent and chemotherapy-resistant disease. Tumor-associated macrophages (TAMs) are a significant component of the tumor microenvironment and include high levels of M2-protumor ...
David Schweer +12 more
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Effect of Podophyllin on Tumor Cells in Tissue Culture.
Experimental Biology and Medicine, 1947 Conclusions1. Podophyllin exerts a selective damaging effect on mouse tumor cells in tissue culture over the concentration range 0.08-20.0 mg/1. 2. This damaging effect is more easilv reversible in normal than in tumor cells. 3. Podophyllotoxin is not as effective as podophyllin in causing selective tumor damage. 4.
Richard A. Ormsbee +2 more
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Versican modulates tumor-associated macrophage properties to stimulate mesothelioma growth
OncoImmunology, 2019 Versican promotes experimental tumor growth through cell- and non cell-autonomous mechanisms. Its role in mesothelioma progression has not been investigated so far.
Apostolos G. Pappas +8 more
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Selective advantage of trisomic human cells cultured in non-standard conditions
Scientific Reports, 2016 An abnormal chromosome number, a condition known as aneuploidy, is a ubiquitous feature of cancer cells. A number of studies have shown that aneuploidy impairs cellular fitness.
Samuel D. Rutledge +9 more
semanticscholar +1 more source