Results 51 to 60 of about 5,932,486 (309)

Tumor-induced myeloid cell plasticity toward lymphatic endothelium [PDF]

, 2009
Tumor-associated lymphangiogenesis contributes to tumor progression by regulating interstitial fluid pressure, transporting immune cells to the tumor site and providing a route for metastatic dissemination.
Baeriswyl, Vanessa
core   +1 more source

Blue light irradiation inhibits the M2 polarization of the cancer-associated macrophages in colon cancer

BMC Cancer
Recent studies have shown that blue light-emitting diode (LED) light has anti-tumor effects, suggesting the possibility of using visible light in cancer therapy.
Toshiaki Yoshimoto, Masaaki Nishi, Shohei Okikawa, Kozo Yoshikawa, Takuya Tokunaga, Toshihiro Nakao, Chie Takasu, Hideya Kashihara, Yuma Wada, Takayuki Noma, Mitsuo Shimada   +10 more
doaj   +1 more source

Effect of Podophyllin on Tumor Cells in Tissue Culture.

Experimental Biology and Medicine, 1947
Conclusions1. Podophyllin exerts a selective damaging effect on mouse tumor cells in tissue culture over the concentration range 0.08-20.0 mg/1. 2. This damaging effect is more easilv reversible in normal than in tumor cells. 3. Podophyllotoxin is not as effective as podophyllin in causing selective tumor damage. 4.
R A, ORMSBEE, I, CORNMAN, R E, BERGER
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Anti-Tumor Effects of TRAIL-Expressing Mesenchymal Stromal Cells in a Mouse Xenograft Model of Human Mesothelioma [PDF]

, 2015
Malignant mesothelioma (MM) remains a highly deadly malignancy with poor treatment option. The MM cells further promote a highly inflammatory microenvironment which contributes to tumor initiation, development, severity, and propagation. We reasoned that
Sage, E, Janes, SM
core  

Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression [PDF]

, 2011
P>Cell senescence is a permanent growth arrest following extended proliferation. Cultured cancer cells including metastatic melanoma cells often appear immortal (proliferate indefinitely), while uncultured benign nevi (moles) show senescence markers ...
Marais, R., Marais, R, Bennett, DC, Julia K. Soo, Chow, J, Hill, L, Chow, J., Ross, ADM, W. Nicol Keith, MacKenzie Ross, A.D., Hossain, M., Bennett, D.C., Heung Chong, W, Hoare, S, Mehnaz Hossain, Soo, JK, Dorothy C. Bennett, Rebecca S. Collinson, Carla Milagre, Milagre, C., David M. Kallenberg, Lucy Hill, Collinson, RS, Mackenzie Ross, AD, Hill, L., Chong, WH, Richard Marais, Kallenberg, DM, Soo, J.K., Jade Chow, Keith, W.N., Hossain, M, Heung Chong, W., Hoare, S., Stacey Hoare, Kallenberg, D.M., Milagre, C, W. Heung Chong, Collinson, R.S., Keith, WN, Alastair D. MacKenzie Ross   +40 more
core   +1 more source

Influence of polyamine analogue DENSPM on cell growth of human SNB19 glioblastoma cells

Chinese Journal of Contemporary Neurology and Neurosurgery, 2011
Objective To investigate the influence of polyamine analogue DENSPM (N1, N11-diethylnorspermine) on cell growth of human SNB19 glioblastoma cells. Methods DENSPM was added into the culture medium of SNB19 cells. MTS assay was used to assess cell survival
Ye TIAN, Bin WANG, Shizhao WANG, Zhengjun WEI, Lin SUN, Rongcai JIANG, Jianning ZHANG   +6 more
doaj  

Inhibiting effect of immunoeffector cells induced by denderitic cells vaccine on growth of PC3 and BEL7402

Journal of Acute Disease, 2018
Objective: To compare effect of immunoprevention or immunotherapy based on denderitic cells (DCs), or supernatants on pancreatic carcinoma and hepatocelluar carcinoma in vitro and in vivo.
Zao-Xi Sun, Zheng-Ke Sun, Kai Li, Ping Long, Ya-Chen Xu, Qiu-Xi Yang, Hai-Rong Huan, Cheng-Yi Sun   +7 more
doaj   +1 more source

Expression of PD-L1 on Monocytes Is a Novel Predictor of Prognosis in Natural Killer/T-Cell Lymphoma

Frontiers in Oncology, 2020
Background: Natural killer/T-cell lymphoma (NKTCL) is a highly aggressive lymphoma with a dismal prognosis, and novel therapeutic targets are urgently needed. Programmed death-ligand 1 (PD-L1) has become a promising therapeutic target for various cancers,
Xue-wen Zhang, Xue-wen Zhang, Xi-wen Bi, Xi-wen Bi, Pan-pan Liu, Pan-pan Liu, Ze-long Liu, Ze-long Liu, Man Nie, Man Nie, Hang Yang, Hang Yang, De-xin Lei, De-xin Lei, Yi Xia, Yi Xia, Wen-qi Jiang, Wen-qi Jiang, Wei-an Zeng, Wei-an Zeng   +19 more
doaj   +1 more source

Reciprocal complementation of the tumoricidal effects of radiation and natural killer cells. [PDF]

PLoS ONE, 2013
The tumor microenvironment is a key determinant for radio-responsiveness. Immune cells play an important role in shaping tumor microenvironments; however, there is limited understanding of how natural killer (NK) cells can enhance radiation effects. This
Kai-Lin Yang, Yu-Shan Wang, Chao-Chun Chang, Su-Chen Huang, Yi-Chun Huang, Mau-Shin Chi, Kwan-Hwa Chi   +6 more
doaj   +1 more source