Results 51 to 60 of about 11,107 (213)

Tumor de Wilms de grandes dimensiones

Anales de Pediatría, 2011
Nina de 5 anos que presentaba abdomialgia difusa de 15 dias e incremento del perimetro abdominal detectado hacia 24 h. Mostraba distension abdominal y se palpaba masa de consistencia firme, no dolorosa, en mesogastrio e hipocondrio y flanco derechos que sobrepasaba 10 cm el reborde costal. Se encontro hipertension arterial. Se detecto LDH de 930 UI/l y
P. Alonso Quintela, D. Mata Zubillaga, V. Recio Pascual, R. Morales Sánchez, D. Naranjo Vivas   +4 more
openaire   +1 more source

ANK1 and EPB41 Variants and the Risk of Steroid‐Induced Osteonecrosis

Arthritis &Rheumatology, EarlyView.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Quantitative RT-PCR-based miRNA profiling of blastemal Wilms’ tumors [PDF]

, 2018
A blastemás Wilms-tumorok kedvezőtlen prognózist mutatnak a kemoterápiára való alacsony érzékenység miatt. Célunk a kísérlet során az volt, hogy hozzájáruljunk a betegség miRNSprofilozásához és megvizsgáljuk, hogy felhasználhatunk-e FFPE mintákat miRNS-
Berki, Zsanett
core  

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Cancer Risk in Marfan Syndrome: A Swedish Population‐Based Cohort Study

International Journal of Cancer, EarlyView.
The cancer risk in Marfan syndrome, an autosomal dominant connective tissue disorder, largely remains to be explored. In this population‐based matched cohort study of 1544 Swedish patients, the overall cancer risk in adults with Marfan syndrome showed no significant increase, except for the risk of endocrine tumours with a nearly threefold increase ...
Ida Nordgren, Anna Skarin Nordenvall, Alexandra Wachtmeister, Fulya Taylan, Yunxia Lu, Christina Norrby, Anna Lindstrand, Giedre Grigelioniene, Giorgio Tettamanti   +8 more
wiley   +1 more source

Tumor de Wilms. Reporte de un caso [PDF]

, 2009
El tumor de Wilms supone la mayor parte de las neoplasias renales de la niñez y se observa con una frecuencia aproximada en ambos sexos y en todas las razas. Es un tumor solitario que surge en cualquier localización de uno u otro riñón.
Ruiz de la Paz, Marino, Montero Álvarez, Lourdes, Ávila Naun, Vilma   +2 more
core   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Tetraploidization in Wilms tumor in an infant [PDF]

, 2010
Genetic instability is frequent in human cancer. Unscheduled tetraploidization can trigger cell transformation and tumorigenesis. We made a cytogenetic analysis by Giemsa-trypsin banding of a stage I, biphasic Wilms tumor diagnosed in a 10-month-old male.
BRASSESCO, M. S., VALERA, E. T., SCRIDELI, C. A., TONE, L. G.   +3 more
core   +1 more source

Primary Wilms tumor of the urinary bladder [PDF]

, 2022
Wilms tumor (WT) can occur at various extrarenal sites; however, the urinary bladder as the primary site is occasional. A 4-year-old-female child presented with difficulty in micturition for the past month.
Peyam, Srinivasan, Srinivasan Peyam, Kushaljit Singh Sodhi, Bal, Amanjit, Nitin James Peters, Nitin James Peters, Trehan, Amita, Amita Trehan, Parkhi, Mayur, Srinivasan Peyam, Peters, Nitin James, Kushaljit Singh Sodhi, Amanjit Bal, Sodhi, Kushaljit Singh, Mayur Parkhi, Amanjit Bal, Mayur Parkhi, Amita Trehan   +17 more
core   +2 more sources