Tumor Immunology and Immunotherapy of Non-Small-Cell Lung Cancer. [PDF]
Historically, non-small-cell lung cancer (NSCLC) has been regarded as a nonimmunogenic tumor; however, recent studies have shown that NSCLCs are among the most responsive cancers to monoclonal antibody immune checkpoint inhibitors (ICIs).
Cascone T+3 more
europepmc +2 more sources
Function of γδ T cells in tumor immunology and their application to cancer therapy. [PDF]
T cells of the γδ lineage are unconventional T cells with functions not restricted to MHC-mediated antigen presentation. Because of their broad antigen specificity and NK-like cytotoxicity, γδ T-cell importance in tumor immunology has been emphasized ...
Park JH, Lee HK.
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Tumor Immunology and Immunotherapy for Head and Neck Squamous Cell Carcinoma. [PDF]
Moskovitz JM, Ferris RL.
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Xanthine dehydrogenase as a prognostic biomarker related to tumor immunology in hepatocellular carcinoma. [PDF]
Background Xanthine dehydrogenase (XDH) is a critical enzyme involved in the oxidative metabolism of purines, pterin and aldehydes and a central component of the innate immune system.
Lin Z+5 more
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Tumor Immunology and Tumor Evolution: Intertwined Histories. [PDF]
Cancer is a complex disease whose outcome depends largely on the cross-talk between the tumor and its microenvironment. Here, we review the evolution of the field of tumor immunology and the advances, in lockstep, of our understanding of cancer as a disease.
J. Galon, Daniela Bruni
semanticscholar +3 more sources
Imaging in Tumor Immunology. [PDF]
Recent advances in immune modulation have made impressive progress in cancer immunotherapy. Because dynamic nature of the immune response often makes it difficult to evaluate therapeutic outcomes, innovative imaging technologies have been developed to enable non-invasive visualization of immune cells and tumors in their microenvironment.
Kim EE, Youn H, Kang KW.
europepmc +4 more sources
Roles for the FCRL6 Immunoreceptor in Tumor Immunology. [PDF]
Members of the Fc receptor-like (FCRL1–6) gene family encode transmembrane glycoproteins that are preferentially expressed by B cells and generally repress responses via cytoplasmic tyrosine-based regulation.
Davis RS.
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Duality of B Cell-CXCL13 Axis in Tumor Immunology. [PDF]
Tumor immunity is a rapidly evolving area of research consisting of many possible permutations of immune cell tumor interactions that are dependent upon cell type, tumor type, and stage in tumor progression.
Rubio AJ, Porter T, Zhong X.
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The Role of Autophagy in Tumor Immunology-Complex Mechanisms That May Be Explored Therapeutically. [PDF]
The tumor microenvironment (TME) is complex, and its composition and dynamics determine tumor fate. From tumor cells themselves, with their capacity for unlimited replication, migration, and invasion, to fibroblasts, endothelial cells, and immune cells ...
de Souza ASC+3 more
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An HNSCC syngeneic mouse model for tumor immunology research and preclinical evaluation. [PDF]
The lack of reliable animal models to assess the safety and efficacy of drugs and to explore the underlying molecular mechanisms is one of the most severe impediments in head and neck squamous cell carcinoma (HNSCC) tumor immunology research.
Fu Y, Tian G, Li J, Zhang Z, Xu K.
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