Function of γδ T cells in tumor immunology and their application to cancer therapy. [PDF]
T cells of the γδ lineage are unconventional T cells with functions not restricted to MHC-mediated antigen presentation. Because of their broad antigen specificity and NK-like cytotoxicity, γδ T-cell importance in tumor immunology has been emphasized ...
Park JH, Lee HK.
europepmc +2 more sources
Xanthine dehydrogenase as a prognostic biomarker related to tumor immunology in hepatocellular carcinoma. [PDF]
Background Xanthine dehydrogenase (XDH) is a critical enzyme involved in the oxidative metabolism of purines, pterin and aldehydes and a central component of the innate immune system.
Lin Z+5 more
europepmc +2 more sources
Tumor immunology meets oncology (TIMO) XVI, July 07-09 2022 in Halle/Saale, Germany. [PDF]
During the TIMO meeting 2022, national and international scientists as well as clinicians gave novel insights as well as perspectives into basic and translational tumor ...
Seliger B.
europepmc +3 more sources
Imaging in Tumor Immunology. [PDF]
Recent advances in immune modulation have made impressive progress in cancer immunotherapy. Because dynamic nature of the immune response often makes it difficult to evaluate therapeutic outcomes, innovative imaging technologies have been developed to enable non-invasive visualization of immune cells and tumors in their microenvironment.
Kim EE, Youn H, Kang KW.
europepmc +4 more sources
Roles for the FCRL6 Immunoreceptor in Tumor Immunology. [PDF]
Members of the Fc receptor-like (FCRL1–6) gene family encode transmembrane glycoproteins that are preferentially expressed by B cells and generally repress responses via cytoplasmic tyrosine-based regulation.
Davis RS.
europepmc +2 more sources
Duality of B Cell-CXCL13 Axis in Tumor Immunology. [PDF]
Tumor immunity is a rapidly evolving area of research consisting of many possible permutations of immune cell tumor interactions that are dependent upon cell type, tumor type, and stage in tumor progression.
Rubio AJ, Porter T, Zhong X.
europepmc +2 more sources
The Role of Autophagy in Tumor Immunology-Complex Mechanisms That May Be Explored Therapeutically. [PDF]
The tumor microenvironment (TME) is complex, and its composition and dynamics determine tumor fate. From tumor cells themselves, with their capacity for unlimited replication, migration, and invasion, to fibroblasts, endothelial cells, and immune cells ...
de Souza ASC+3 more
europepmc +2 more sources
An HNSCC syngeneic mouse model for tumor immunology research and preclinical evaluation. [PDF]
The lack of reliable animal models to assess the safety and efficacy of drugs and to explore the underlying molecular mechanisms is one of the most severe impediments in head and neck squamous cell carcinoma (HNSCC) tumor immunology research.
Fu Y, Tian G, Li J, Zhang Z, Xu K.
europepmc +2 more sources
Exosome-mediated regulation of tumor immunology. [PDF]
Exosomes are representative extracellular vesicles (EV) derived from multivesicular endosomes (MVE) and have been described as new particles in the communication of neighborhood and/or distant cells by serving as vehicles for transfer between cells of ...
Seo N, Akiyoshi K, Shiku H.
europepmc +2 more sources
Strange Attractor in Immunology of Tumor Growth [PDF]
The time delayed cytotoxic T-lymphocyte response on the tumor growth has been developed on the basis of discrete approximation (2-dimensional map). The growth kinetic has been described by logistic law with growth rate being the bifurcation parameter.
Margarita Voitikova
arxiv +3 more sources