Results 11 to 20 of about 3,216,819 (320)

Tumor Immunology and Immunotherapy of Non-Small-Cell Lung Cancer. [PDF]

open access: yesCold Spring Harb Perspect Med, 2022
Historically, non-small-cell lung cancer (NSCLC) has been regarded as a nonimmunogenic tumor; however, recent studies have shown that NSCLCs are among the most responsive cancers to monoclonal antibody immune checkpoint inhibitors (ICIs).
Cascone T   +3 more
europepmc   +2 more sources

Function of γδ T cells in tumor immunology and their application to cancer therapy. [PDF]

open access: yesExp Mol Med, 2021
T cells of the γδ lineage are unconventional T cells with functions not restricted to MHC-mediated antigen presentation. Because of their broad antigen specificity and NK-like cytotoxicity, γδ T-cell importance in tumor immunology has been emphasized ...
Park JH, Lee HK.
europepmc   +2 more sources

Xanthine dehydrogenase as a prognostic biomarker related to tumor immunology in hepatocellular carcinoma. [PDF]

open access: yesCancer Cell Int, 2021
Background Xanthine dehydrogenase (XDH) is a critical enzyme involved in the oxidative metabolism of purines, pterin and aldehydes and a central component of the innate immune system.
Lin Z   +5 more
europepmc   +2 more sources

Tumor Immunology and Tumor Evolution: Intertwined Histories. [PDF]

open access: yesImmunity, 2020
Cancer is a complex disease whose outcome depends largely on the cross-talk between the tumor and its microenvironment. Here, we review the evolution of the field of tumor immunology and the advances, in lockstep, of our understanding of cancer as a disease.
J. Galon, Daniela Bruni
semanticscholar   +3 more sources

Imaging in Tumor Immunology. [PDF]

open access: yesNucl Med Mol Imaging, 2021
Recent advances in immune modulation have made impressive progress in cancer immunotherapy. Because dynamic nature of the immune response often makes it difficult to evaluate therapeutic outcomes, innovative imaging technologies have been developed to enable non-invasive visualization of immune cells and tumors in their microenvironment.
Kim EE, Youn H, Kang KW.
europepmc   +4 more sources

Roles for the FCRL6 Immunoreceptor in Tumor Immunology. [PDF]

open access: yesFront Immunol, 2020
Members of the Fc receptor-like (FCRL1–6) gene family encode transmembrane glycoproteins that are preferentially expressed by B cells and generally repress responses via cytoplasmic tyrosine-based regulation.
Davis RS.
europepmc   +2 more sources

Duality of B Cell-CXCL13 Axis in Tumor Immunology. [PDF]

open access: yesFront Immunol, 2020
Tumor immunity is a rapidly evolving area of research consisting of many possible permutations of immune cell tumor interactions that are dependent upon cell type, tumor type, and stage in tumor progression.
Rubio AJ, Porter T, Zhong X.
europepmc   +2 more sources

The Role of Autophagy in Tumor Immunology-Complex Mechanisms That May Be Explored Therapeutically. [PDF]

open access: yesFront Oncol, 2020
The tumor microenvironment (TME) is complex, and its composition and dynamics determine tumor fate. From tumor cells themselves, with their capacity for unlimited replication, migration, and invasion, to fibroblasts, endothelial cells, and immune cells ...
de Souza ASC   +3 more
europepmc   +2 more sources

An HNSCC syngeneic mouse model for tumor immunology research and preclinical evaluation. [PDF]

open access: yesInt J Mol Med, 2020
The lack of reliable animal models to assess the safety and efficacy of drugs and to explore the underlying molecular mechanisms is one of the most severe impediments in head and neck squamous cell carcinoma (HNSCC) tumor immunology research.
Fu Y, Tian G, Li J, Zhang Z, Xu K.
europepmc   +2 more sources

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