Results 221 to 230 of about 408,319 (335)
An HNSCC syngeneic mouse model for tumor immunology research and preclinical evaluation. [PDF]
Fu Y, Tian G, Li J, Zhang Z, Xu K.
europepmc +1 more source
A zinc‐coordinated nanogel assembly is reported that co‐delivers three enzymes to regulate glucose, oxidative stress, and oxygen levels. This system mimics natural enzyme cascades to reprogram the wound environment after pancreatectomy. In a post‐pancreatectomy mouse model, it accelerates healing by reducing infection, promoting blood vessel growth ...
Yedong Ma+9 more
wiley +1 more source
The tumor strikes back: New data on expression of the CD95(APO-1/Fas) receptor/ligand system may cause paradigm changes in our view on drug treatment and tumor immunology [PDF]
Peter H. Krammer
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Advances and Strategies in Enhancing mRNA Cancer Vaccines
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang+4 more
wiley +1 more source
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao+6 more
wiley +1 more source
Lymphatic vessels, miRNAs, and CAR T cells in tumor immunology. [PDF]
Jiang X.
europepmc +1 more source
The critical role of Th1-dominant immunity in tumor immunology [PDF]
Takashi Nishimura+8 more
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Label‐Free FET Based Biosensor for Detection of Engineered CAR T‐Cells at Single Cell Resolution
A silicon nanowire field‐effect transistor (SiNW FET) biosensor that allows for label‐free, real‐time detection and quantification of engineered Chimeric Antigen Receptor (CAR) T‐cells at single‐cell resolution is presented. By mimicking the CAR‐specific antigen interface, the platform provides highly selective analysis of individual cell surface ...
Trang Anh Nguyen‐Le+5 more
wiley +1 more source
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen+2 more
wiley +1 more source
"Tumor immunology meets oncology (TIMO) XV", April 25th-27th 2019, Halle/Saale, Germany. [PDF]
Steven A, Massa C, Seliger B.
europepmc +1 more source