Results 21 to 30 of about 403,248 (353)

The role of MUC16 in tumor biology and tumor immunology in ovarian cancer. [PDF]

BMC Cancer
Yang N, Zhou X, Gong Y, Deng Z.
europepmc   +2 more sources

Dynamic Tumor Immunology-on-a-Chip for Peripheral Blood-Derived Tumor-Reactive T Cell Expansion. [PDF]

Research (Wash D C)
Shou X, Yu Y, Wu D, Lu P, Zhao M, Zhao Y.   +5 more
europepmc   +2 more sources

Author Correction: Interferon signaling and ferroptosis in tumor immunology and therapy. [PDF]

NPJ Precis Oncol
Hu W, Zhao Z, Du J, Jiang J, Yang M, Tian M, Zhao P.   +6 more
europepmc   +2 more sources

Tumor Immunology and Immunotherapy for Head and Neck Squamous Cell Carcinoma. [PDF]

J Dent Res, 2018
Moskovitz JM, Ferris RL.
europepmc   +3 more sources

Tumor-derived microvesicles modulate antigen cross-processing via reactive oxygen species-mediated alkalinization of phagosomal compartment in dendritic cells [PDF]

, 2017
Dendritic cells (DCs) are the only antigen-presenting cells able to prime naïve T cells and cross-prime antigen-specific CD8+ T cells. Their functionality is a requirement for the induction and maintenance of long-lasting cancer immunity.
Aurelia Rughetti, Chiara Napoletano, Fabio Altieri, Federico Battisti, Filippo Bellati, Filippo Bellati, Francesca Belleudi, Giulio Caracciolo, Hassan Rahimi Koshkaki, Ilaria Grazia Zizzari, Ilary Ruscito, Ilary Ruscito, Maria Rosaria Torrisi, Maria Rosaria Torrisi, Marianna Nuti, Pierluigi Benedetti Panici, Sara Palchetti   +16 more
core   +11 more sources

KLF4-mediated upregulation of the NKG2D ligand MICA in acute myeloid leukemia: a novel therapeutic target identified by enChIP

Cell Communication and Signaling, 2023
The immunoreceptor NKG2D, which is expressed on NK cells and T cell subsets is critically involved in tumor immune surveillance. This applies in particular to acute myeloid leukemia (AML), which evades immune detection by downregulation of NKG2D ligands (
Reem Alkhayer, Viviane Ponath, Miriam Frech, Till Adhikary, Johannes Graumann, Andreas Neubauer, Elke Pogge von Strandmann   +6 more
doaj   +1 more source

Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast tumors

OncoImmunology, 2023
The clinical successes of immune checkpoint blockade (ICB) in advanced cancer patients have recently spurred the clinical implementation of ICB in the neoadjuvant and perioperative setting. However, how neoadjuvant ICB therapy affects the systemic immune
Olga S. Blomberg, Kevin Kos, Lorenzo Spagnuolo, Olga I. Isaeva, Hannah Garner, Max D. Wellenstein, Noor Bakker, Danique E.M. Duits, Kelly Kersten, Sjoerd Klarenbeek, Cheei-Sing Hau, Daphne Kaldenbach, Elisabeth A.M. Raeven, Kim Vrijland, Marleen Kok, Karin E. de Visser   +15 more
doaj   +1 more source

Algorithmic asymptotic analysis: extending the arsenal of cancer immunology modeling [PDF]

Journal of Theoretical Biology Volume 534, 7 February 2022, 110975, 2021
The recent advances in cancer immunotherapy boosted the development of tumor-immune system models aiming to provide mechanistic understanding and indicate more efficient treatment regimes. However, the complexity of such models, their multi-scale dynamics and their overparameterized character renders them inaccessible for wide utilization. In this work,
arxiv   +1 more source

MicroRNA analysis of Natural Killer cell-derived exosomes: the microRNA let-7b-5p is enriched in exosomes and participates in their anti-tumor effects against pancreatic cancer cells

OncoImmunology, 2023
Natural Killer (NK) cells are important components of the immune system in the defense against tumor growth and metastasis. They release exosomes containing proteins and nucleic acids, including microRNAs (miRNAs).
Anna Laura Di Pace, Andrea Pelosi, Piera Filomena Fiore, Nicola Tumino, Francesca Besi, Linda Quatrini, Silvia Santopolo, Paola Vacca, Lorenzo Moretta   +8 more
doaj   +1 more source

Membrane and Soluble CD137 in Systemic Lupus Erythematosus: Role as Biomarkers for Disease Activity

Journal of Immunology Research, 2023
Objective. The role of T cells in the pathogenesis of systemic lupus erythematosus (SLE) has recently gained attention. Costimulatory molecules are membrane proteins strictly associated with T-cell receptor (TCR), acting by activating or inhibiting T ...
Fulvia Ceccarelli, Francesco Natalucci, Alessandra Di Filippo, Giulio Olivieri, Chiara Napoletano, Aurelia Rughetti, Marianna Nuti, Ilaria Grazia Zizzari, Fabrizio Conti   +8 more
doaj   +1 more source