Results 31 to 40 of about 438,171 (330)

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer

open access: yesCancer Cell International, 2023
Background Lack of Schlafen family member 11 (SLFN11) expression has been recently identified as a dominant genomic determinant of response to DNA damaging agents in numerous cancer types.
Christophe Michel Raynaud   +13 more
doaj   +1 more source

Neural regulation of cancer: from mechanobiology to inflammation. [PDF]

open access: yes, 2016
Despite recent progress in cancer research, the exact nature of malignant transformation and its progression is still not fully understood. Particularly metastasis, which accounts for most cancer death, is a very complex process, and new treatment ...
Kim, Tae-Hyung   +2 more
core   +2 more sources

Natural killer cell response to chemotherapy-stressed cancer cells: Role in tumor immunosurveillance. [PDF]

open access: yes, 2017
Natural killer (NK) cells are innate cytotoxic lymphoid cells that actively prevent neoplastic development, growth, and metastatic dissemination in a process called cancer immunosurveillance.
Borrelli, Cristiana   +5 more
core   +1 more source

Structure-functional activity relationship of β-glucans from the perspective of immunomodulation : a mini-review [PDF]

open access: yes, 2020
β-Glucans are a heterogeneous group of glucose polymers with a common structure comprising a main chain of β-(1,3) and/or β-(1,4)-glucopyranosyl units, along with side chains with various branches and lengths.
Baruah, Sri Kartik   +4 more
core   +2 more sources

Tumor Immunology

open access: bronzeJournal of Vaccines & Vaccination, 2013
Mohamed L. Elsaie
openaire   +2 more sources

CTLA-4 and PD-1 ligand gene expression in epithelial thyroid cancers [PDF]

open access: yes, 2018
The dysregulation of PD-1 ligands (PD-L1 and PD-L2) and CTLA-4 ligands (CD80 and CD86) represents a tumor strategy to escape the immune surveillance. Here, the expression of PD-L1, PD-L2, CD80 and CD86 was evaluated at mRNA level in 94 patients affected ...
Antonelli, Alessandro   +15 more
core   +3 more sources

Isolation of Mononuclear Cell Populations from Ovarian Carcinoma Ascites

open access: yesBio-Protocol, 2017
Ovarian cancer is one of the most fatal tumors in women. Due to a lack of symptoms and adequate screening methods, patients are diagnosed at advanced stages with extensive tumor burden (Jelovac and Armstrong, 2011).
Christina Wefers   +6 more
doaj   +1 more source

Tumor-associated macrophages promote intratumoral conversion of conventional CD4+ T cells into regulatory T cells via PD-1 signalling

open access: yesOncoImmunology, 2022
While regulatory T cells (Tregs) and macrophages have been recognized as key orchestrators of cancer-associated immunosuppression, their cellular crosstalk within tumors has been poorly characterized.
Kevin Kos   +11 more
doaj   +1 more source

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