Results 41 to 50 of about 3,216,819 (320)
Cell Communication and Signaling, 2023 The immunoreceptor NKG2D, which is expressed on NK cells and T cell subsets is critically involved in tumor immune surveillance. This applies in particular to acute myeloid leukemia (AML), which evades immune detection by downregulation of NKG2D ligands (
Reem Alkhayer +6 more
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OncoImmunology, 2023 The clinical successes of immune checkpoint blockade (ICB) in advanced cancer patients have recently spurred the clinical implementation of ICB in the neoadjuvant and perioperative setting. However, how neoadjuvant ICB therapy affects the systemic immune
Olga S. Blomberg +15 more
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Engineered exosomes for studies in tumor immunology
Immunological Reviews, 2022 Exosomes are a type of extracellular vesicle (EV) with diameters of 30–150 nm secreted by most of the cells into the extracellular spaces and can alter the microenvironment through cell‐to‐cell interactions by fusion with the plasma membrane and ...
A. Alptekin +4 more
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Membrane and Soluble CD137 in Systemic Lupus Erythematosus: Role as Biomarkers for Disease Activity
Journal of Immunology Research, 2023 Objective. The role of T cells in the pathogenesis of systemic lupus erythematosus (SLE) has recently gained attention. Costimulatory molecules are membrane proteins strictly associated with T-cell receptor (TCR), acting by activating or inhibiting T ...
Fulvia Ceccarelli +8 more
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eLife, 2020 Tumor immunology is undergoing a renaissance due to the recent profound clinical successes of tumor immunotherapy. These advances have coincided with an exponential growth in the development of –omics technologies. Armed with these technologies and their
Nathan E Reticker-Flynn +1 more
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OncoImmunology, 2021 Cancer-associated fibroblasts (CAFs) and hypoxia are central players in the complex process of tumor cell-stroma interaction and are involved in the alteration of the anti-tumor immune response by impacting both cancer and immune cell populations ...
Linda Ziani +3 more
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Gastroenterology, 2021 Chronic inflammation is a known risk factor for gastrointestinal cancer. The evidence that nonsteroidal anti-inflammatory drugs (NSAIDs) suppress the incidence, growth, and metastasis of gastrointestinal cancer supports the concept that an NSAID target ...
Dingzhi Wang +3 more
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OncoImmunology, 2023 Natural Killer (NK) cells are important components of the immune system in the defense against tumor growth and metastasis. They release exosomes containing proteins and nucleic acids, including microRNAs (miRNAs).
Anna Laura Di Pace +8 more
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IX Forum on Translational Immunology and Cancer Immuno-therapy (FIT Cancer 9)
OncoImmunology, 2023 /INTRODUCTIONTumor immunology and cancer immunotherapy is a growing field, continuously evolving. Different types of immunotherapies have been implemented over last decade in the standard of care across several tumor types.
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Mesenchymal stem cell therapy for liver disease: full of chances and challenges
Cell & Bioscience, 2020 Liver disease is a major health problem that endangers human health worldwide. Currently, whole organ allograft transplantation is the gold standard for the treatment of end-stage liver disease.
Xue Yang +5 more
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