Results 111 to 120 of about 343,340 (395)

Tumor-Infiltrating Lymphocytes—Location for Prognostic Evaluation [PDF]

open access: yesClinical Cancer Research, 2019
Abstract Tumor-infiltrating lymphocytes (TIL) are crucial for the success of immunotherapy, and their density can predict prognosis. It has now been shown that computer-based analysis of the spatial organization of TILs adds prognostic value in early-stage non–small cell lung cancer, possibly improving the treatment algorithm to prevent ...
Michael, Peled, Amir, Onn, Roy S, Herbst
openaire   +2 more sources

Tumor Infiltrating Lymphocytes and Macrophages Improve Survival in Microsatellite Unstable Colorectal Cancer

open access: yesScientific Reports, 2019
Due to the loss of DNA repair mechanisms in colorectal cancer (CRC) with microsatellite instability (MSI), somatic mutations accumulate within DNA; making them more prone to attack by tumor infiltrating lymphocytes (TIL) and macrophages.
Sumana Narayanan   +6 more
semanticscholar   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

Polyphenon E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells [PDF]

open access: yes, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Note: In this manuscript as well as in the original published version of this article the word "Polyphenon" was incorrectly spelled in the title as ...
Adrian J. Thrasher   +14 more
core   +2 more sources

Prognostic Impact of Tumor-Infiltrating Lymphocytes and Neutrophils on Survival of Patients with Upfront Resection of Pancreatic Cancer

open access: yesCancers, 2019
In patients with pancreatic ductal adenocarcinoma (PDAC), the tumor microenvironment consists of cellular and stromal components that influence prognosis. Hence, tumor-infiltrating lymphocytes (TILs) may predict prognosis more precisely than conventional
R. Miksch   +8 more
semanticscholar   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Tumor infiltrating lymphocytes in malignant melanoma - allies or foes?

open access: yesBiomedical Papers, 2020
This is an overview of current problematics regarding the role of tumor infiltrating lymphocytes (TILs) in malignant melanomas. Various and often conflicting data have been published, correlating tumor type, stage, prognosis, as well as sex and age of ...
Vladimir Zidlik   +2 more
doaj   +1 more source

Quantifying tumour-infiltrating lymphocyte subsets : a practical immuno-histochemical method [PDF]

open access: yes, 2007
Background: Efficient histological quantification of tumour-infiltrating T and B lymphocyte (TIL) subsets in archival tissues would greatly facilitate investigations of the role of TIL in human cancer biology. We sought to develop such a method. Methods:
Alison J. Gray   +19 more
core   +1 more source

2022-RA-711-ESGO Association of PET-CT tumor metabolic metrics and intraepithelial and stromal tumor-infiltrating lymphocytes in locally advanced cervical cancer prior to concurrent chemo-radiotherapy [PDF]

open access: bronze, 2022
Alejandra Martínez   +10 more
openalex   +1 more source

Multiplex Quantitative Analysis of Tumor-Infiltrating Lymphocytes and Immunotherapy Outcome in Metastatic Melanoma

open access: yesClinical Cancer Research, 2019
Purpose: Because durable response to programmed cell death 1 (PD-1) inhibition is limited to a subset of melanoma patients, new predictive biomarkers could have clinical utility.
Pok Fai Wong   +8 more
semanticscholar   +1 more source

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