Results 121 to 130 of about 124,855 (301)

Ten-year clinical outcome, toxicity and compliance of dose-dense sequential adjuvant administration of cyclophosphamide & epirubicin followed by docetaxel in patients with early breast cancer: A hellenic cooperative oncology group observational study (HE 10/10) with concurrent investigation of significance of tumor infiltrating lymphocytes

Breast
Background: Dose-dense sequential (dds) chemotherapy has changed the clinical outcome of patients with early breast cancer (BC). To investigate the impact of dose intensity (DI) in the adjuvant setting of BC, this observational trial (HE 10/10) was ...
Foteinos-Ioannis Dimitrakopoulos, Anna Goussia, Georgia-Angeliki Koliou, Katerina Dadouli, Anna Batistatou, Helen P. Kourea, Mattheos Bobos, Petroula Arapantoni-Dadioti, Olympia Tzaida, Triantafyllia Koletsa, Sofia Chrisafi, Maria Sotiropoulou, Alexandra Papoudou-Bai, Irene Nicolaou, Antonia Charchanti, Davide Mauri, Gerasimos Aravantinos, Ioannis Binas, Eleni Res, Amanda Psyrri, Dimitrios Pectasides, Dimitrios Bafaloukos, Anna Koumarianou, Iliada Bompolaki, Georgios Rigakos, Charisios Karanikiotis, Angelos Koutras, Flora Zagouri, Helen Gogas, George Fountzilas   +29 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cells-0

, 2011
Copyright information:Taken from "Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cells"http://www.biomedcentral.com/1472-6750/7/70BMC Biotechnology 2007;7():70-70.Published online 18 Oct ...
Daniela Santapaola (59975), Fiorella Petronzelli (58573), Angela Pelliccia (58576), Rita De Santis (58578), Olga Minenkova (5454), Giorgia Monteriù (5445), Valeria D'Alessio (58575), Emiliano Pavoni (5442), Anna Maria Anastasi (58574)   +8 more
core   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

A Novel Role of Metalloproteinase in Cancer-Mediated Immunosuppression

, 2009
Depressed immune responses have been observed frequently in cancer patients. In a variety of human malignancies, the expression of interleukin-2 receptor alpha (IL-2R alpha) on activated tumor-infiltrating lymphocytes was down-regulated.
黃思誠;許世明;連晃駿, HUANG, SU-CHENG;HSU, SU-MING;LIEN, HUANG-CHUN   +1 more
core  

Evaluation of tumor infiltrating lymphocytes in breast cancer [PDF]

, 2018
BACKGROUND: Tumor infiltrating lymphocytes (TILs) were evaluated in many cancers like ovarian tumors, endometrial tumors, colon cancer and melanoma. Now there is increasing trend in evaluating TILs in breast cancer. Tumor infiltrating lymphocytes gives
Suganya, U
core  

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

The Impact of Nutritional Status and Tumor-Infiltrating Lymphocytes (CD4+ and CD8+) on Chemotherapy Response in Colorectal Cancer Patients

Kiki Lukman,1 Rhandy Septianto,1 Reno Rudiman,1 Tommy Ruchimat,1 Yunia Sribudiani,2 Prapanca Nugraha,1 Etis Primastari,3 Deny Budiman1 1Surgery Department, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; 2Department of Biomedical ...
Sribudiani Y, Budiman D, Lukman K, Ruchimat T, Rudiman R, Primastari E, Septianto R, Nugraha P   +7 more
core  

tumor-infiltrating lymphocyte

Citation: 'tumor-infiltrating lymphocyte' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13761 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual ...
openaire   +1 more source

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source