Results 121 to 130 of about 267,145 (352)
Tumor-specific cytolysis by lymphocytes infiltrating human melanomas. [PDF]
, 1989 Suzanne L. Topalian +2 more
openalex +1 more source
Advanced Functional Materials, EarlyView.A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee +12 more
wiley +1 more source
Tumor infiltrating lymphocytes: The regulator of melanoma evolution.
Oncology Letters, 2019 Melanoma is the most severe type of skin cancer and its incidence has increased in the last decades. In the United States, it is the 6th most common cancer in both men and women. Prognosis for patients with melanoma depends on the stage of the disease at
Mihaela Antohe +14 more
semanticscholar +1 more source
Advances and prospects in tumor infiltrating lymphocyte therapy
Discover OncologyTumor-infiltrating lymphocyte (TIL) therapy in adoptive T-cell therapy (ACT) has already caused durable regression in a variety of cancer types due to T-cell persistence, clinical activity, and duration of objective response and safety. TILs are composed of polyclonal effector T-cells specific to heterogenetic tumor antigens, reasonably providing a ...
Xu Qiu +7 more
openaire +3 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?
BMC Cancer, 2012 Tumor infiltrating lymphocytes (TILs) are commonly detected in breast tumors but their bearing on disease outcome is uncertain. The importance of TILs appears to be subtype-specific and varies depending on the histologic characteristics of the tumor.
Krell Jonathan +2 more
doaj +1 more source
Shared human melanoma antigens. Recognition by tumor-infiltrating lymphocytes in HLA-A2.1-transfected melanomas. [PDF]
, 1992 Yutaka Kawakami +4 more
openalex +1 more source
TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Intraperitoneal administration of immunogenic Toll‐like receptor agonist‐modified mesoporous silica nanoparticles leads to rapid internalization by ascites myeloid cells with trafficking to fat‐associated lymphoid clusters. Activation of myeloid cells counters suppressive immune mechanisms associated with peritoneal metastasis, leading to regional and ...
Ben Marwedel +15 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche +16 more
wiley +1 more source
Asian Pacific Journal of Cancer Biology, 2019 For more progress in head and neck squamous cell carcinoma (HNSCC) immuno-oncology, further understanding of interactions between tumor and immune system as well as factors in the tumor microenvironment is required.
Marzieh Norouzian, Sima Balouchi-Anaraki
doaj +1 more source