Results 231 to 240 of about 267,145 (352)

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
wiley   +1 more source

Pathologist-Read vs AI-Driven Assessment of Tumor-Infiltrating Lymphocytes in Melanoma.

JAMA Netw Open
Aung TN, Liu M, Su D, Shafi S, Boyaci C, Steen S, Tsiknakis N, Vidal JM, Maher N, Micevic G, Tan SX, Vesely MD, Nourmohammadi S, Bai Y, Djureinovic D, Wong PF, Bates K, Chan NNN, Gavirelatou N, He M, Burela S, Barna R, Bosic M, Bräutigam K, Illabochaca I, Chenhao Z, Gama J, Kreis B, Mohacsi R, Pillar N, Pinto J, Poulios C, Toli MA, Tzoras E, Bracero Y, Bosisio F, Cserni G, Dema A, Fortarezza F, Gonzalez MS, Gullo I, Queipo Gutiérrez FJ, Hacihasanoglu E, Jovic V, Lazar B, Olinca M, Neppl C, Oliveira RC, Pezzuto F, Gomes Pinto D, Plotar V, Pop O, Rau T, Skok K, Sun W, Serbes ED, Solass W, Stanowska O, Szasz M, Szymonski K, Thimm F, Vignati D, Vigdorovits A, Prieto V, Sinnberg T, Wilmott J, Cowper S, Warrell J, Saenger Y, Hartman J, Plummer J, Osman I, Rimm DL, Acs B.   +73 more
europepmc   +1 more source

Tumor-infiltrating lymphocytes as predictive biomarkers in neoadjuvant treatment of HER2-positive breast cancer. [PDF]

Oncologist
Kınıkoğlu O, Altıntaş YE, Yıldız A, Akdağ G, Bal H, Yaşar ZY, Özkerim U, Yıldız HŞ, Öksüz S, Tünbekici S, Doğan A, Işık D, Yaşar A, Başoğlu T, Sürmeli H, Odabaş H, Turan N.   +16 more
europepmc   +1 more source

Tumor-Infiltrating Lymphocytes and Perforation in Colon Cancer Predict Positive Response to 5-Fluorouracil Chemotherapy [PDF]

, 2008
M. J. Morris, Cameron Platell, Barry Iacopetta   +2 more
openalex   +1 more source

Bispecific Antibody Targeting VEGF/TGF‐β Synergizes with Local Radiotherapy: Turning Tumors from Cold to Inflamed and Amplifying Abscopal Effects

Advanced Science, EarlyView.
Y332D, a bispecific antibody that simultaneously blockades VEGF and TGF‐β, counteracted negative RT effects that are attributed to the upregulation of TGF‐β and VEGF, as well as further enhanced the immunostimulatory effects of RT, thereby reprograming the TME from immune “cold” to inflamed state and forming an effective in‐situ vaccine that eradicate ...
Lijuan Lyu, Ming Yi, Ji Chen, Jing Zhang, Xiaobin Ma, Xiaojun Zhang, Liang Zeng, Yan Xue, Haimei Wen, Yujiao Deng, Pengfei Zhou, Kongming Wu, Huafeng Kang, Zhijun Dai   +13 more
wiley   +1 more source

Prognostic impact of tumor-infiltrating lymphocytes in HER2+ metastatic breast cancer receiving first-line treatment. [PDF]

NPJ Breast Cancer
Taurelli Salimbeni B, Giudici F, Pescia C, Berton Giachetti PPM, Scafetta R, Zagami P, Marra A, Trapani D, Esposito A, Scagnoli S, Cerbelli B, Botticelli A, Munzone E, Fusco N, Criscitiello C, Curigliano G.   +15 more
europepmc   +1 more source

Association of Ovarian Tumor Epithelium Coexpressing HLA-DR and CA-125 Antigens with Tumor Infiltrating Cytotoxic T Lymphocytes

, 2003
Norihiro Matsushita, Mohammad Ghazizadeh, Hideki Konishi, Tsutomu Araki   +3 more
openalex   +2 more sources

Tumor‐infiltrating lymphocytes derived from human renal cell carcinoma: Clonal analysis of its characteristics [PDF]

, 2008
Tomoyuki Shimabukuro, Katsusuke Naito
openalex   +1 more source

Targeting Glutamine Metabolism Transporter SLC25A22 Enhances CD8+ T‐Cell Function and Anti‐PD‐1 Therapy Efficacy in Cervical Squamous Cell Carcinoma: Integrated Metabolomics, Transcriptomics and T‐Cell‐Incorporated Tumor Organoid Studies

Advanced Science, EarlyView.
Through metabolomic and transcriptomic analyses, a glutamine‐enriched, immunosuppressive microenvironment is identified in cervical squamous cell carcinoma (CSCC), highlighting the glutamine transporter SLC25A22 as a key regulator of glutamine metabolism, immune checkpoint activation, and CD8+ T‐cell cytotoxicity.
Tingting Ren, Junjun Qiu, Fanghua Chen, Qian Jiang, Qinqin Liu, Tong Wu, Hua Jiang, Keqin Hua   +7 more
wiley   +1 more source

PD-1 involvement in CD8+ tumor-infiltrating lymphocytes in patients with colonic-derived peritoneal adenocarcinoma. [PDF]

Braz J Med Biol Res
Hu H, Zhang M.
europepmc   +1 more source