Results 231 to 240 of about 343,340 (395)

Insight Into the Significance of CD8+ Tumor-Infiltrating Lymphocytes in Lung Adenocarcinoma. [PDF]

Thorac Cancer
Shiomi K, Ichinoe M, Ushiwata A, Nagashio R, Hayashi S, Sonoda D, Kondo Y, Tamagawa S, Mitsuhashi S, Sugiyama Y, Naito M, Mikubo M, Shirasawa M, Nakahara Y, Sato T, Naoki K, Murakumo Y, Eshima K.   +17 more
europepmc   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Association of Tumor-Infiltrating Lymphocytes (TILs) With Pathological Complete Response to Neoadjuvant Therapy in Breast Cancer. [PDF]

Cureus
Ul Ain N, Ishaq S, Islam MK, Badar Q, Chaudhry K, Adil T, Bangash SA.   +6 more
europepmc   +1 more source

Characterization of PD‐1 upregulation on tumor‐infiltrating lymphocytes in human and murine gliomas and preclinical therapeutic blockade [PDF]

, 2017
Joost Dejaegher, Tina Verschuere, Ellen Vercalsteren, Louis Boon, Jonathan Cremer, Raf Sciot, Stefaan Van Gool, Steven De Vleeschouwer   +7 more
openalex   +1 more source

Prognostic impact of tumor microvessels in intrahepatic cholangiocarcinoma: association with tumor-infiltrating lymphocytes

Modern Pathology, 2020
K. Yugawa, S. Itoh, T. Yoshizumi, Norifumi Iseda, T. Tomiyama, T. Toshima, N. Harada, Kenichi Kohashi, Y. Oda, M. Mori   +9 more
semanticscholar   +1 more source

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

Advanced Science, EarlyView.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen, Zhenzhen Wang, Liqiang Song, Qianqian Chen, Hang Zhang, Tao Pan, Jianli Pan, Sheng Zhao, Ting Shang, Hong'en Xu, Xing Lv, Jing Li, Fei Kang, Yongzhan Nie, Feng Zhao, Lei Shi, Zheng Wang   +16 more
wiley   +1 more source

Minimally expanded breast cancer tumor-infiltrating-lymphocytes provide guidance for therapeutic selection. [PDF]

Front Immunol
Aran A, Lázaro G, Marco V, Peg V, Faus M, Garrigós L, Pérez-García J, Cortés J, Martí M.   +8 more
europepmc   +1 more source

FOXP3 expression in tumor cells and tumor-infiltrating lymphocytes is associated with breast cancer prognosis

, 2013
Miki Takenaka, Naoko Seki, Uhi Toh, Satoshi Hattori, Akihiko Kawahara, Tomohiko Yamaguchi, Keiko Koura, Ryuji Takahashi, Hiroko Otsuka, Hiroki Takahashi, Nobutaka Iwakuma, Shino Nakagawa, Teruhiko Fujii, Tetsuro Sasada, Rin Yamaguchi, Hirohisa Yano, Kazuo Shirouzu, Masayoshi Kage   +17 more
openalex   +2 more sources

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

Clinical characteristics and prognostic impact of HER2-ultralow breast cancer and tumor-infiltrating lymphocytes (TILs). [PDF]

BMC Cancer
Takada K, Kashiwagi S, Nishikawa M, Kochi A, Watanabe C, Kinoshita H, Ogisawa K, Shibutani M, Morisaki T.   +8 more
europepmc   +1 more source