Results 211 to 220 of about 115,861 (261)

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

Advanced Science, EarlyView.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu, Xuan Lu, Yuquan Wang, Haihua Ji, Ying Zhang, Yiqun Wan, Hao Wan   +6 more
wiley   +1 more source

A computer vision method to evaluate tumor-infiltrating lymphocytes and multiparametric modeling of neoadjuvant systemic therapy response in breast cancer. [PDF]

Ther Adv Med Oncol
Bielecki M, Lu FI, Vo A, Rakovitch E, Jerzak KJ, Salgado R, Karshafian R, Tran WT.   +7 more
europepmc   +1 more source

Minimally expanded breast cancer tumor-infiltrating-lymphocytes provide guidance for therapeutic selection. [PDF]

Front Immunol
Aran A, Lázaro G, Marco V, Peg V, Faus M, Garrigós L, Pérez-García J, Cortés J, Martí M.   +8 more
europepmc   +1 more source

Phase I trial of locoregional administration of autologous tumor-infiltrating lymphocytes in patients with uveal melanoma and liver metastases (the HAITILS trial). [PDF]

J Immunother Cancer
Nelson A, Riise R, Alsén S, Wong A, Carlson P, Edman S, Holgersson J, Olofsson Bagge R, Johansson I, Sadik M, Edenbrandt L, Nilsson LM, Nilsson JA, Ny L.   +13 more
europepmc   +1 more source

Clinical characteristics and prognostic impact of HER2-ultralow breast cancer and tumor-infiltrating lymphocytes (TILs). [PDF]

BMC Cancer
Takada K, Kashiwagi S, Nishikawa M, Kochi A, Watanabe C, Kinoshita H, Ogisawa K, Shibutani M, Morisaki T.   +8 more
europepmc   +1 more source

Title: AI-based quantification of tumor-infiltrating lymphocytes with integrative transcriptomics in ovarian clear cell carcinoma: JGOG3025-TR1/A1 study. [PDF]

Cancer Immunol Immunother
Hamada K, Hamanishi J, Ueda A, Takamatsu S, Yoshihara K, Nagasawa T, Seki T, Kikuchi A, Fujimoto E, Taki M, Yamanoi K, Murakami R, Kumada K, Oda K, Shimada M, Okamoto A, Mandai M, Matsumura N.   +17 more
europepmc   +1 more source

Combined assessment of stromal tumor infiltrating lymphocytes and tumor peroxiredoxin 4 expression improved prognostic stratification in postoperative pancreatic cancer patients. [PDF]

Diagn Pathol
Liu Y, Han J, Shioya A, Jiao W, Okuro M, Ito T, Yamada S.   +6 more
europepmc   +1 more source

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Tumor-Infiltrating Lymphocytes

The Cancer Journal, 2015
Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs) in combination with lymphodepletion and high-dose interleukin 2 has shown reproducible objective response rates of approximately 50% in patients with highly advanced, refractory metastatic melanoma.
Michal J, Besser, Ronnie, Shapira-Frommer, Jacob, Schachter   +2 more
openaire   +3 more sources

Tumor microenvironment and lymphocyte infiltration

Cancer Immunology, Immunotherapy, 2012
There is ample evidence that the presence of tumor-infiltrating T lymphocytes is associated with a favorable prognostic in patients. These observations suggest that a limiting step to immune resistance and immunotherapy could be the capacity of tumor-specific T cells to reach tumor bed.
Rahir, Gwendoline, Moser, Muriel
openaire   +3 more sources

Clonal dynamics of tumor-infiltrating lymphocytes

European Journal of Immunology, 2005
The presence of tumor-infiltrating lymphocytes (TIL) provides important evidence of anti-tumor immunity in vivo. However, TIL are usually not sufficient for inhibiting tumor growth. We explored the spatial and temporal aspects of clonal accumulation of TIL using RT-PCR/single-strand conformation polymorphism analysis.
Rong, Yu, Keishi, Fujio, Hiroyuki, Tahara, Yasuto, Araki, Kazuhiko, Yamamoto   +4 more
openaire   +2 more sources