Results 211 to 220 of about 124,855 (301)

Nano‐Confined Radical Anion as An NIR‐II Photothermal Immunogenic Amplifier for In Situ Cancer Vaccination

Advanced Science, EarlyView.
A nano‐confined radical anion acts as a photothermal immunogenic amplifier. Kinetically stabilized nanoparticles couple high near‐infrared‐II (NIR‐II) photothermal efficacy with glutathione (GSH) depletion to boost reactive oxygen species (ROS) and immunogenic cell death (ICD).
Mengxin Mu, Mengyu Guo, Jun Guan, Xiaofeng He, Mingdi Hu, Fene Gao, Klaus Müllen, Chendong Ji, Chunying Chen, Meizhen Yin   +9 more
wiley   +1 more source

Potent Cytotoxic Tumor-Infiltrating Lymphocytes Can Be Generated from Immune-Excluded Chondrosarcomas Using Regulatable Membrane-Bound IL15. [PDF]

Cancer Immunol Res
Ao Z, Al-Marayaty R, Aksoy BA, Obeidin F, Burga R, Attar S, Peabody T, Hermida de Viveiros P, Kei Ng JC, Jing W, Shinglot H, Zhang A, Ocando AV, Roy N, Kulkarni G, Alvarado A, Sun D, Sethi DK, Ols M, Ter Meulen J, Pollack SM.   +20 more
europepmc   +1 more source

Few Tumor Infiltrating Lymphocytes [PDF]

, 2020
openaire   +1 more source

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source

Estrogen receptor α expression in tumor-infiltrating lymphocytes from patients with endometrial cancer. [PDF]

Oncol Lett
Jedryka MA, Slawek A, Kubik P, Lorek D, Kedzierska AE, Czekanski A, Matkowski R, Chelmonska-Soyta A.   +7 more
europepmc   +1 more source

Tumor Infiltrating Lymphocyte Therapy [PDF]

, 2020
openaire   +1 more source

S100A8/A9‐High Macrophages Activate Intestinal Fibroblasts via mCCL6/hCCL15‐CCR1 Axis to Drive Intestinal Fibrosis in Crohn's Disease

Advanced Science, EarlyView.
S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang, Jiayun Wang, Junjie Lin, Ziping Ye, Geyujia Zhou, Jingjing Ma, Junjian Sun, Jiang Yu, Yingdi Zhang, Nana Tang, Chunhua Jiao, Xiaojing Zhao, Hongjie Zhang   +12 more
wiley   +1 more source

Insight Into the Significance of CD8+ Tumor-Infiltrating Lymphocytes in Lung Adenocarcinoma. [PDF]

Thorac Cancer
Shiomi K, Ichinoe M, Ushiwata A, Nagashio R, Hayashi S, Sonoda D, Kondo Y, Tamagawa S, Mitsuhashi S, Sugiyama Y, Naito M, Mikubo M, Shirasawa M, Nakahara Y, Sato T, Naoki K, Murakumo Y, Eshima K.   +17 more
europepmc   +1 more source

NIR‐II Light‐Triggered Electron Flow Initiates Cuproptosis‐Centered Thermoelectric‐Immunotherapy for Breast Cancer

Advanced Science, EarlyView.
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan, Qin Fan, Shushu Chu, Shining Yang, Yuechao Yang, Chenxi Zhang, Jinqiao Zhang, Xinran Qu, Yiju Wei, Xin Wang, Ziliang Dong   +10 more
wiley   +1 more source

A Cross-Sectional Study of CD163 Expression and CD8-Positive Tumor-Infiltrating Lymphocytes in Glial Tumors at a Tertiary Care Center. [PDF]

Cureus
Nair A, Kishore N.
europepmc   +1 more source