Results 31 to 40 of about 267,145 (352)

Association between tumor-infiltrating lymphocytes and sentinel lymph node positivity in thin melanoma [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2019
: Background: Sentinel lymph node biopsy in thin invasive primary cutaneous melanoma (up to 1mm thick) is a controversial subject. The presence of tumor-infiltrating lymphocytes could be a factor to be considered in the decision to perform this ...
Fernando De Marco dos Santos   +5 more
doaj   +1 more source

Marsdenia tenacissima enhances immune response of tumor infiltrating T lymphocytes to colorectal cancer

open access: yesFrontiers in Immunology, 2023
IntroductionTumor-infiltrating T lymphocytes in the tumor microenvironment are critical factors influencing the prognosis and chemotherapy outcomes. As a Chinese herbal medicine, Marsdenia tenacissima extract (MTE) has been widely used to treat cancer in
Ben Yi   +15 more
doaj   +1 more source

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

open access: yesnpj Breast Cancer, 2020
Stromal tumor-infiltrating lymphocytes (sTILs) are important prognostic and predictive biomarkers in triple-negative (TNBC) and HER2-positive breast cancer. Incorporating sTILs into clinical practice necessitates reproducible assessment.
Z. Kos   +255 more
semanticscholar   +1 more source

ASSESSMENT OF STROMAL AND INTRA-EPITHELIAL TUMOR INFILTRATING LYMPHOCYTES IN COLORECTAL CARCINOMA AT ARMED FORCES INSTITUTE OF PATHOLOGY

open access: yesPakistan Armed Forces Medical Journal, 2021
Objective: To conduct a morphological evaluation quantitatively of two types of tumor-infiltrating lymphocyte populations, including those located in the stroma and intraepithelial cancer structures, in patients with colorectal cancer.
Amna Ameer   +3 more
doaj   +1 more source

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group

open access: yesnpj Breast Cancer, 2020
Assessment of tumor-infiltrating lymphocytes (TILs) is increasingly recognized as an integral part of the prognostic workflow in triple-negative (TNBC) and HER2-positive breast cancer, as well as many other solid tumors.
M. Amgad   +257 more
semanticscholar   +1 more source

DIMEimmune: Robust estimation of infiltrating lymphocytes in CNS tumors from DNA methylation profiles

open access: yesOncoImmunology, 2021
The interaction of CNS tumors with infiltrating lymphocytes plays an important role in their initiation and progression and might be related to therapeutic responses.
Sepehr Safaei   +4 more
doaj   +1 more source

Tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy with or without carboplatin in human epidermal growth factor receptor 2-positive and triple-negative primary breast cancers.

open access: yesJournal of Clinical Oncology, 2015
PURPOSE Modulation of immunologic interactions in cancer tissue is a promising therapeutic strategy. To investigate the immunogenicity of human epidermal growth factor receptor 2 (HER2) -positive and triple-negative (TN) breast cancers (BCs), we ...
C. Denkert   +29 more
semanticscholar   +1 more source

Tumor-infiltrating T lymphocytes: friends or foes? [PDF]

open access: yesLaboratory Investigation, 2006
The prognostic significance of tumor-infiltrating lymphocytes (TILs) has been a longstanding topic of debate. In cases where TILs have improved patient outcome, T lymphocytes are recognized as the main effectors of antitumor immune responses. However, recent studies have revealed that a subset of CD4(+) T cells, referred to as CD4(+)CD25(+) regulatory ...
Ping Yu, Yang Xin Fu
openaire   +2 more sources

CTL Attenuation Regulated by PS1 in Cancer-Associated Fibroblast

open access: yesFrontiers in Immunology, 2020
Objective: Cancer-associated fibroblasts (CAFs) were associated with tumor progression in the tumor microenvironment (TME). However, their immunosuppressive roles in protecting cancer cells from the attack by cytotoxic T lymphocytes (CTLs) are not fully ...
Hongyu Zhang   +23 more
doaj   +1 more source

Clinical significance of tumor-infiltrating lymphocytes in breast cancer

open access: yesJournal of Immunotherapy for Cancer, 2016
Tumor infiltrating lymphocytes (TIL) play an essential role in mediating response to chemotherapy and improving clinical outcomes in all subtypes of breast cancer.
S. Stanton, M. Disis
semanticscholar   +1 more source

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