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Dynamic roles of tumor-infiltrating B lymphocytes in cancer immunotherapy
Cancer Immunology, ImmunotherapyThe amazing diversity of B cells within the tumor microenvironment is the basis for the diverse development of B cell-based immunotherapies. Here, we focus on elucidating the mechanisms of tumor intervention mediated by four tumor-infiltrating B ...
Shishengnan Song +5 more
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Evaluation of tumor infiltrating lymphocytes in breast carcinomas
Journal of Pathology of Nepal, 2022 Background: Among the parameters that have a prognostic and/or predictive significance to therapeutic response, in the case of breast carcinoma, the study of tumor-infiltrating lymphocytes in breast carcinomas is emerging.
Shovana Karki +2 more
doaj +1 more source
Tumor-Infiltrating Lymphocytes in Melanoma [PDF]
Current Oncology Reports, 2012 Adoptive cell therapy using tumor-infiltrating lymphocytes (TIL) is arguably the most effective treatment for patients with metastatic melanoma. With higher response rates than ipilimumab or IL-2, and longer durations of response than vemurafenib, TIL therapy carries the potential to transform current outcomes in melanoma, while also defining the way ...
Sylvia, Lee, Kim, Margolin
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Tumor-infiltrating lymphocytes in colorectal carcinoma
Journal of Pathology of Nepal, 2021 Background: Immunotherapy has become an important modality of treatment for CRC. The cells contributing to an effective immune response are CD8+ T cells of tumor-infiltrating lymphocytes.
Shovana Karki, Sanjib Pariyar
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CD8+ T-cell lymphocytes infiltration predict clinical outcomes in Wilms’ tumor
Tumor Biology, 2020 The abundance and location of CD8+ tumor-infiltrating lymphocytes demonstrate important facets of the anticancer immune response. CD8-expressing lymphocytes have been used in immunotherapy for multiple cancers.
Keykhosro Mardanpour +4 more
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Tumor infiltrating lymphocytes and radiological picture of the tumor
Medical Oncology, 2023 AbstractTumor microenvironment (TME) is a complex entity that includes besides the tumor cells also a whole range of immune cells. Among various populations of immune cells infiltrating the tumor, tumor infiltrating lymphocytes (TILs) are a population of lymphocytes characterized by high reactivity against the tumor component.
Karolina Frankowska +3 more
openaire +2 more sources
Bioengineered, 2022 Tumor-infiltrating lymphocytes (TILs) are vital elements of the tumor microenvironment (TME), and the anti-tumor activity of TILs on colorectal cancer (CRC) has been a topic of concern. However, the characteristics and prognosis of the various types of lymphocyte infiltration in CRC have not been fully explained.
Miao Qin +11 more
openaire +2 more sources
Life, 2020 Immunotherapy is a highly promising approach for the treatment of gastric cancer, the third-leading cause of overall cancer death worldwide. In particular, tumor-infiltrating lymphocytes and peripheral blood mononuclear cells are believed to mediate host
Wei-Ming Chen +6 more
doaj +1 more source
T lymphocytes from patients with primary biliary cirrhosis produce reduced amounts of lymphotoxin, tumor necrosis factor and interferon-gamma upon mitogen stimulation [PDF]
, 1992 Primary biliary cirrhosis (PBC) is considered an autoimmune disease characterized by destruction of small intrahepatic bile ducts by lymphocytes. Altered functions of these lymphocytes might reflect an abnormal immune response leading to tissue damage ...
Eisenburg, Josef +9 more
core +1 more source
Biomedicines, 2022 Oropharynx squamous cell carcinoma (OPSCC) is of special interest because human papilloma virus (HPV) and/or smoking cause this disease. Influxes of inflammatory cells into such tumors are known to vary with prognoses.
Hilde Haave +7 more
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