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Critical Care Nurse, 2022
Background Tumor lysis syndrome is a life-threatening oncologic emergency in adult and pediatric patients with hematologic cancer. It occurs most often in malignancies with rapid cell turnover and large tumor burden, but its incidence has risen in solid tumors.
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Background Tumor lysis syndrome is a life-threatening oncologic emergency in adult and pediatric patients with hematologic cancer. It occurs most often in malignancies with rapid cell turnover and large tumor burden, but its incidence has risen in solid tumors.
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Seminars in Thrombosis and Hemostasis, 2007
Tumor lysis syndrome (TLS) is an important metabolic disorder frequently encountered in the management of a variety of cancers including lymphoma, leukemia, and neuroblastoma. Delayed recognition can result in a variety of biochemical abnormalities resulting in life-threatening complications such as renal failure, arrhythmias, and seizures ...
Ramon V, Tiu +3 more
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Tumor lysis syndrome (TLS) is an important metabolic disorder frequently encountered in the management of a variety of cancers including lymphoma, leukemia, and neuroblastoma. Delayed recognition can result in a variety of biochemical abnormalities resulting in life-threatening complications such as renal failure, arrhythmias, and seizures ...
Ramon V, Tiu +3 more
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The Indian Journal of Pediatrics, 2012
Tumor lysis syndrome (TLS) refers to the constellation of deranged metabolic state, characterized by hyperkalemia, hyperphosphatemia, hyperuricemia, hypocalcemia, and/or azotemia, secondary to rapid breakdown of tumor cells. It is a life threatening emergency that typically follows administration of chemotherapy or may be spontaneous.
Aruna, Rajendran +3 more
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Tumor lysis syndrome (TLS) refers to the constellation of deranged metabolic state, characterized by hyperkalemia, hyperphosphatemia, hyperuricemia, hypocalcemia, and/or azotemia, secondary to rapid breakdown of tumor cells. It is a life threatening emergency that typically follows administration of chemotherapy or may be spontaneous.
Aruna, Rajendran +3 more
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Medical and Pediatric Oncology, 1979
AbstractRapid tumor lysis may produce acute complications including systemic metabolic disturbances and hemorrhage in sites involved by tumor. We have observed two cases of acute pancreatitis induced by the lysis of lymphoma that involved the pancreas. This previously unreported cause of pancreatitis must be added to the list of potential complications
R J, Spiegel, I T, Magrath
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AbstractRapid tumor lysis may produce acute complications including systemic metabolic disturbances and hemorrhage in sites involved by tumor. We have observed two cases of acute pancreatitis induced by the lysis of lymphoma that involved the pancreas. This previously unreported cause of pancreatitis must be added to the list of potential complications
R J, Spiegel, I T, Magrath
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Seminars in Oncology Nursing, 1999
To review the pathophysiology, clinical manifestations, and management of tumor lysis syndrome.Published articles, case reports, and book chapters on tumor lysis syndrome.Tumor lysis syndrome is a very serious and sometimes life-threatening complication of cancer treatment. Identification of patients at risk and initiation of preventative interventions
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To review the pathophysiology, clinical manifestations, and management of tumor lysis syndrome.Published articles, case reports, and book chapters on tumor lysis syndrome.Tumor lysis syndrome is a very serious and sometimes life-threatening complication of cancer treatment. Identification of patients at risk and initiation of preventative interventions
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Tumor Lysis Syndrome in Solid Tumors
Supportive Cancer Therapy, 2005Tumor lysis syndrome (TLS) consists of acute hyperuricemic nephropathy, hyperphosphatemia, hypocalcemia, hyperkalemia, and increased serum creatinine. It can be part of the disease presentation, especially in aggressive hematologic malignancies, or a part of the chemotherapy response. There are relatively few reports of TLS in solid tumors.
Frank E, Mott +3 more
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Seminars in Hematology, 2001
Tumor lysis syndrome (TLS) is a constellation of metabolic disturbances observed in tumors with high cell turnover. It is associated with significant morbidity and mortality. TLS is characterized by the increased release of intracellular contents (uric acid, potassium, phosphorus) into the extracellular compartment, which can overwhelm the body's ...
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Tumor lysis syndrome (TLS) is a constellation of metabolic disturbances observed in tumors with high cell turnover. It is associated with significant morbidity and mortality. TLS is characterized by the increased release of intracellular contents (uric acid, potassium, phosphorus) into the extracellular compartment, which can overwhelm the body's ...
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Seminars in Oncology, 2001
Abstract The electrolyte abnormalities and metabolic derangements associated with ATLS are a serious consequence in patients with both hematologic malignancies and solid tumors. While concern is primarily for those with highly proliferative hematopoietic disorders following treatment with exquisitely responsive chemotherapy, the practitioner should ...
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Abstract The electrolyte abnormalities and metabolic derangements associated with ATLS are a serious consequence in patients with both hematologic malignancies and solid tumors. While concern is primarily for those with highly proliferative hematopoietic disorders following treatment with exquisitely responsive chemotherapy, the practitioner should ...
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Nursing Made Incredibly Easy!, 2010
Tumor lysis syndrome(TLS)is a serious complication of anti-cancer chemotherapy due to the spontaneous or therapyrelated rapid lysis of malignant cells. TLS is characterized by hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia, which result in acute renal failure and metabolic acidosis.
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Tumor lysis syndrome(TLS)is a serious complication of anti-cancer chemotherapy due to the spontaneous or therapyrelated rapid lysis of malignant cells. TLS is characterized by hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia, which result in acute renal failure and metabolic acidosis.
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Gan to kagaku ryoho. Cancer & chemotherapy, 2009
Recently, the ASCO guideline has added TLS. Prevention and recognition of the disease and state are important. Molecular targeting drugs, small molecule tyrosine kinase inhibitors and monoclonal antibodies induced rapid regression of the tumors and carry a risk of TLS.
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Recently, the ASCO guideline has added TLS. Prevention and recognition of the disease and state are important. Molecular targeting drugs, small molecule tyrosine kinase inhibitors and monoclonal antibodies induced rapid regression of the tumors and carry a risk of TLS.
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