Results 231 to 240 of about 3,620,379 (402)

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Tumor Microenvironment in Melanoma-Characteristic and Clinical Implications. [PDF]

Int J Mol Sci
Sikorski H, Żmijewski MA, Piotrowska A.
europepmc   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

A biofabricated 3D cancer-stroma tumor microenvironment model. [PDF]

Biofabrication
Romanazzo S, Tian P, Jalandhra GK, Doshi RB, Gooding JJ, Kilian KA.   +5 more
europepmc   +1 more source

Interruption of tumor dormancy by a transient angiogenic burst within the tumor microenvironment

, 2006
Stefano Indraccolo, L. Stievano, Sonia Minuzzo, Valeria Tosello, Giovanni Esposito, Erich Piovan, Rita Zamarchi, Luigi Chieco‐Bianchi, Alberto Amadori   +8 more
openalex   +1 more source

RRP9 Promotes Esophageal Squamous Cell Carcinoma Progression through E2F1 Transcriptional Regulation of CDK1

Advanced Biology, EarlyView.
The study reveals that RRP9 is abnormally highly expressed in ESCC tissues and is closely associated with poor prognosis in patients. Furthermore, it is found that RRP9 promotes ESCC progression through enhancing the E2F1‐mediated transcriptional regulation of CDK1.
Gang He, Yilong Wan, Yanbo Zhu, Bo Peng, Shengxiang Shao, Xinyi Zou, Zhenyu Han, Jiaxi Li, Sheng Ju, Xin Tong, Jun Zhao, Hansi Liang, Liuqing Zhang, Jiashi Xiong, Dong Jiang   +14 more
wiley   +1 more source

Impact of the tumor microenvironment on survival in anaplastic thyroid carcinoma. [PDF]

Sci Rep
Rana C, Mishra P, Singh K, Ramakant P, Mishra A, Qayoom S, Kumar G, Mishra J, Verma K.   +8 more
europepmc   +1 more source

Elucidating the Mechanisms of IL-12 Mediated Alterations of the Tumor Microenvironment [PDF]

, 2007
Elizabeth W. Sorensen
openalex   +1 more source

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment [PDF]

, 2008
Bo Huang, Lei Zhang, Gui‐Mei Zhang, Dong Li, Chuanwang Song, Bo Li, Yanyan Liu, Ye Yuan, Jay C. Unkeless, Huabao Xiong, Zuo‐Hua Feng   +10 more
openalex   +1 more source