Results 231 to 240 of about 664,473 (309)

PLX3397 attenuated tumor growth and remodeled tumor microenvironment of recurrent glioblastoma. [PDF]

Sci Rep
Yang C, Cai L, Xiang X, Zhu X, Liu C, Liao J, Zhang Z, Li M.   +7 more
europepmc   +1 more source

Context-Dependent Regulation of Peripheral Nerve Abundance by the PI3K Pathway in the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma [PDF]

Karam Khorani, Sebastian Burkart, Christopher Weusthof, Rui Han, Siyuan Liang, Fabian Stögbauer, Jochen Heß   +6 more
openalex   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

Pediatric tumor microenvironment: developmental dynamics and therapy resistance. [PDF]

Front Oncol
George NG, Rishi B, Dhanda H, Joseph GT, Swain SK, Kaur M, Kushwaha N, Kamal R, Tanwar P, Zaheer S, Zaman S, Singh A, Siraj F, Misra A.   +13 more
europepmc   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Tumor Microenvironment-Responsive Nanomedicines for Potentiating Cancer Immunotherapy. [PDF]

Adv Sci (Weinh)
Huang Q, Tong F, Chen J, Kayumov M, Lv Y, Shi Y, Ye B, Gao H.   +7 more
europepmc   +1 more source

Data Sheet 1_FGA modulates immune infiltration and tumor progression via SLC7A11/xCT-mediated disulfidptosis in the tumor microenvironment of lung adenocarcinoma.zip

Gen Li (743590), Qiuping Li (456520), Sheng Yang (592249), Dongmei Guo (3814906), Yanling Tao (18854232), Yan Jia (198590)   +5 more
openalex   +1 more source

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

Advanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji, Ruichen Zhang, Dongyi Xu, Patrick C. A. van der Wel, Alessia Lasorsa, Guotai Li, Fangze Guo, Qihui Zhou, Patrick van Rijn   +8 more
wiley   +1 more source

Serglycin's role in primary liver cancer: insights into tumor microenvironment and macrophage interaction. [PDF]

Front Immunol
Lian Q, Ma C, Wang X, Wang J, Zeng J, Zhang J, Li Y.   +6 more
europepmc   +1 more source