Results 11 to 20 of about 314,005 (303)

Influence of ?S-globin haplotypes and hydroxyurea on tumor necrosis factor-alpha levels in sickle cell anemia

Revista Brasileira de Hematologia e Hemoterapia, 2014
Background: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha.
Marília Rocha Laurentino, Pedro Aurio Maia Filho, Maritza Cavalcante Barbosa, Izabel Cristina Justino Bandeira, Lilianne Brito da Silva Rocha, Romelia Pinheiro Gonçalves   +5 more
doaj   +2 more sources

Expression of tumor necrosis factor-alpha–converting enzyme and tumor necrosis factor-alpha in human myocarditis

Journal of the American College of Cardiology, 2000
We determined whether tumor necrosis factor-alpha-converting enzyme (TACE) is expressed with tumor necrosis factor-alpha (TNF-alpha) in myocarditis.Tumor necrosis factor-alpha-converting enzyme, which has recently been identified as belonging to the family of metalloproteinase disintegrin proteins, is responsible for the conversion of TNF-alpha ...
Satoh, Mamoru, Nakamura, Motoyuki, Satoh, Hidetoshi, Saitoh, Hidenori, Segawa, Ikuo, Hiramori, Katsuhiko   +5 more
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Tumor Necrosis Factor-Alpha and Age-Related Pathologies

Архивъ внутренней медицины, 2020
Modern concepts about the «inflammaging» and the role of subclinical inflammation in various age-associated pathology are described in the review. Particular attention is paid to the tumor necrosis factor-α, a key cytokine that plays an important role in
S. V. Topolyanskaya
doaj   +1 more source

Eicosanoids and tumor necrosis factor-alpha in the kidney [PDF]

Prostaglandins & Other Lipid Mediators, 2012
The thick ascending limb of Henle's loop (TAL) is capable of metabolizing arachidonic acid (AA) by cytochrome P450 (CYP450) and cyclooxygenase (COX) pathways and has been identified as a nephron segment that contributes to salt-sensitive hypertension. Previous studies demonstrated a prominent role for CYP450-dependent metabolism of AA to products that ...
Ferreri, Nicholas R., Hao, Shoujin, Pedraza, Paulina L., Escalante, Bruno, Vio, Carlos P.   +4 more
openaire   +5 more sources

Profile of Tumor Necrosis Factor Alpha Levels in Childhood Malignancy with Febrile Neutropenia [PDF]

, 2022
Infection is a significant cause of morbidity and mortality in childhood malignancy with Febrile Neutropenia (FN). Tumor Necrosis Factor-Alpha (TNF-α) is involved in host defense against bacterial invasion.
Tigor Pandapotan Sianturi, Puspa Wardhani, -, I Dewa Gede Ugrasena, -   +2 more
core  

Alopecia secondary to anti-tumor necrosis factor-alpha therapy [PDF]

Anais Brasileiros de Dermatologia, 2015
Biologic drugs represent a substantial progress in the treatment of chronic inflammatory immunologic diseases. However, its crescent use has revealed seldom reported or unknown adverse reactions, mainly associated with anti-tumor necrosis factor (anti ...
Lara Beatriz Prata Ribeiro, Juliana Carlos Gonçalves Rego, Bruna Duque Estrada, Paula Raso Bastos, Juan Manuel Piñeiro Maceira, Celso Tavares Sodré   +5 more
doaj   +1 more source

Development of low blood glucose readings in nine non-diabetic patients treated with tumor necrosis factor-alpha inhibitors: a case series

Journal of Medical Case Reports, 2012
Introduction Treatment with various biological agents in disease states such as rheumatoid arthritis has been associated with multiple side effects. Whereas many of these are frequently reported in the literature, hypoglycemia, a possible side effect of ...
Czajkowska Jadwiga B, Shutty Brandon, Zito Susan   +2 more
doaj   +1 more source

Evaluation of Tumor Necrosis Factor Alpha Polymorphism Frequencies in Endometriosis [PDF]

International Journal of Fertility and Sterility, 2015
Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are ...
Roshanak Abutorabi, Azar Baradaran, Fatemeh Sadat Mostafavi, Yasaman Zarrin, Farahnaz Mardanian   +4 more
doaj   +1 more source

Synergistic and antagonistic effects of TNF-[alpha] and IGF-I in heart failure : "in vitro" and "in vivo" study of cardiac and skeletal muscle [PDF]

, 2006
Cardiovascular diseases are a major cause of morbidity and mortality in industrialized countries. All forms of myocardial injury first lead to compensatory hypertrophy, which eventually progresses to heart failure.
Murigande, Claire
core   +1 more source

Tumor Necrosis Factor Alpha-Mediated Asthma? [PDF]

International Archives of Allergy and Immunology, 2012
Thus the pathophysiology of allergic asthma is traditionally explained by mast celland/or Th2 cell-mediated airway inflammation, which is a manifestation of the acquired immune response. On the other hand, recent studies have identified various other important molecules associated with phenotypes of asthma, including tumor necrosis factor (TNF)[2, 3] ,
openaire   +2 more sources