Results 11 to 20 of about 6,121,735 (304)

Tumor necrosis factor-alpha inhibitor treatment for sarcoidosis

Therapeutics and Clinical Risk Management, 2008
José Luis Callejas-Rubio, Lourdes López-Pérez, Norberto Ortego-CentenoUnit of Autoimmune Systemic Diseases, Hospital Clinico San Cecilio, Granada, SpainAbstract: Sarcoidosis is a chronic multisystem disease of unknown ...
José Luis Callejas-Rubio, Lourdes López-Pérez, Norberto Ortego-Centeno   +2 more
doaj   +1 more source

Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor ΚB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells

Drug Design, Development and Therapy, 2014
Jinchao Li,1,* Jun Li,2,* Ye Yue,1 Yiping Hu,1 Wenxiang Cheng,1 Ruoxi Liu,3 Xiaohua Pan,4 Peng Zhang1 1Center for Translational Medicine Research and Development, Shenzhen Institute of Advanced Technology, Chinese Academy of Science, Shenzhen ...
Li J, Li J, Yue Y, Hu Y, Cheng W, Liu R, Pan X, Zhang P   +7 more
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Profile of Tumor Necrosis Factor Alpha Levels in Childhood Malignancy with Febrile Neutropenia [PDF]

, 2022
Infection is a significant cause of morbidity and mortality in childhood malignancy with Febrile Neutropenia (FN). Tumor Necrosis Factor-Alpha (TNF-α) is involved in host defense against bacterial invasion.
Tigor Pandapotan Sianturi, Puspa Wardhani, -, I Dewa Gede Ugrasena, -   +2 more
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Locally up-regulated lymphotoxin a, not systemic tumor necrosis factor a, is the principle mediator of murine cerebral malaria [PDF]

, 2002
Cerebral malaria (CM) causes death in children and nonimmune adults. TNF-{alpha} has been thought to play a key role in the development of CM. In contrast, the role of the related cyto-kine lymphotoxin {alpha} (LT{alpha}) in CM has been overlooked.
Sanjeet Sawhney, Mynott, T.L., Kaye, PM, De Souza, J Brian, Bickle, Quentin D, Kaye, P.M., Engwerda, C.R., Sawhney, Sanjeet, Engwerda, CR, Tracey L. Mynott, Paul M. Kaye, Christian R. Engwerda, Bickle, Q.D., Sawhney, S, Bickle, QD, Mynott, Tracey L, De Souza, JB, Mynott, TL, Engwerda, Christian R, Sawhney, S., J. Brian De Souza, Quentin D. Bickle, Kaye, Paul M, De Souza, J.B.   +23 more
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Alopecia secondary to anti-tumor necrosis factor-alpha therapy [PDF]

Anais Brasileiros de Dermatologia, 2015
Biologic drugs represent a substantial progress in the treatment of chronic inflammatory immunologic diseases. However, its crescent use has revealed seldom reported or unknown adverse reactions, mainly associated with anti-tumor necrosis factor (anti ...
Lara Beatriz Prata Ribeiro, Juliana Carlos Gonçalves Rego, Bruna Duque Estrada, Paula Raso Bastos, Juan Manuel Piñeiro Maceira, Celso Tavares Sodré   +5 more
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Expression of tumor necrosis factor-alpha–converting enzyme and tumor necrosis factor-alpha in human myocarditis

Journal of the American College of Cardiology, 2000
We determined whether tumor necrosis factor-alpha-converting enzyme (TACE) is expressed with tumor necrosis factor-alpha (TNF-alpha) in myocarditis.Tumor necrosis factor-alpha-converting enzyme, which has recently been identified as belonging to the family of metalloproteinase disintegrin proteins, is responsible for the conversion of TNF-alpha ...
Satoh, Mamoru, Nakamura, Motoyuki, Satoh, Hidetoshi, Saitoh, Hidenori, Segawa, Ikuo, Hiramori, Katsuhiko   +5 more
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Tumor Necrosis Factor Alpha-Mediated Asthma? [PDF]

International Archives of Allergy and Immunology, 2012
Thus the pathophysiology of allergic asthma is traditionally explained by mast celland/or Th2 cell-mediated airway inflammation, which is a manifestation of the acquired immune response. On the other hand, recent studies have identified various other important molecules associated with phenotypes of asthma, including tumor necrosis factor (TNF)[2, 3] ,
openaire   +2 more sources

УГНЕТЕНИЕ ПРОТИВООПУХОЛЕВОЙ ЦИТОТОКСИЧЕСКОЙ АКТИВНОСТИ ДЕНДРИТНЫХ КЛЕТОК У БОЛЬНЫХ ЗЛОКАЧЕСТВЕННЫМИ ЛИМФОМАМИ, ОБУСЛОВЛЕННОЕ ИЗМЕНЕННОЙ ЭКСПРЕССИЕЙ ФАКТОРА НЕКРОЗА ОПУХОЛИ АЛЬФА [PDF]

, 2016
Recent research revealed dendritic cells (DCs) to have direct antitumor cytotoxic activity and to inhibit the growth and proliferation of tumor cells in vitro. The aim of the present study was to investigate the association between the cytotoxic activity
I. V. Kryuchkova, G. Yu. Ushakova, V. V. Sergeevicheva, И. В. Крючкова, М. А. Тихонова, D. S. Batorova, Д. С. Баторова, С. А. Сизикова, S. A. Sizikova, Т. В. Тыринова, Г. Ю. Ушакова, E. R. Chernykh, A. A. Ostanin, В. В. Сергеевичева, А. А. Останин, T. V. Tyrinova, M. A. Tikhonova, O. Yu. Leplina, Е. Р. Черных, О. Ю. Леплина   +19 more
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Development of low blood glucose readings in nine non-diabetic patients treated with tumor necrosis factor-alpha inhibitors: a case series

Journal of Medical Case Reports, 2012
Introduction Treatment with various biological agents in disease states such as rheumatoid arthritis has been associated with multiple side effects. Whereas many of these are frequently reported in the literature, hypoglycemia, a possible side effect of ...
Czajkowska Jadwiga B, Shutty Brandon, Zito Susan   +2 more
doaj   +1 more source

Evaluation of Tumor Necrosis Factor Alpha Polymorphism Frequencies in Endometriosis [PDF]

International Journal of Fertility and Sterility, 2015
Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are ...
Roshanak Abutorabi, Azar Baradaran, Fatemeh Sadat Mostafavi, Yasaman Zarrin, Farahnaz Mardanian   +4 more
doaj   +1 more source