Results 21 to 30 of about 314,005 (303)

Tumor necrosis factor alpha and mesangial cells

Kidney International, 1992
Bacterial infections promote important alterations in immune, hemodynamic, and metabolic function which can result in irreversible shock. These changes are mediated by host-secreted cytokines rather than by direct action of the endotoxin lipopolysaccharide (LPS) derived from the cell wall of bacteria.
Baud, Laurent, Fouqueray, Bruno, Philippe, Carole, Amrani, Abdelaziz   +3 more
openaire   +2 more sources

Understanding the immunopathogenic bases and the clinical approach of the periodic syndrome associated with the tumor necrosis receptor, TRAPS

Iatreia, 2018
Tumor necrosis factor receptor periodic syndrome (TRAPS) is characterized by episodes of fever of more than 10 days of duration, migratory myalgias, pseudocellulitis, abdominal pain and bipalpebral edema.
Moreno Zuluaga, Catalina, Velásquez Lopera, Margarita María   +1 more
doaj   +1 more source

The concentration of tumor necrosis factor alpha in periapical lesions [PDF]

Stomatološki glasnik Srbije, 2014
Introduction. The balance between proinflammatory and anti-inflammatory cytokines plays an important role in the pathogenesis of chronic periapical lesions.
Popović Jelena, Cvetković Tatjana, Džopalić Tanja, Mitić Aleksandar, Nikolić Marija, Barac Radomir, Živković Slavoljub   +6 more
doaj   +1 more source

The assessment of TNF-α interaction with oligopeptide Trp-Asn-Trp-Val in vitro [PDF]

Вестник Витебского государственного медицинского университета, 2022
The hyperproduction of TNF-α in the human body is a pathogenetic factor of many diseases development. The widespread clinical use of anticytokine drugs based on antibodies has a number of limitations.
T.V. Ryabtseva, A.D. Tahanovich, D.A. Makarevich   +2 more
doaj   +1 more source

Tumor necrosis factor alpha in sleep regulation

Sleep Medicine Reviews, 2018
This review details tumor necrosis factor alpha (TNF) biology and its role in sleep, and describes how TNF medications influence sleep/wake activity. Substantial evidence from healthy young animals indicates acute enhancement or inhibition of endogenous brain TNF respectively promotes and inhibits sleep.
Rockstrom, Matthew D, Chen, Liangyu, Taishi, Ping, Nguyen, Joseph T, Gibbons, Cody M, Veasey, Sigrid C, Krueger, James M   +6 more
openaire   +4 more sources

Implication of Tumor Necrosis Factor - Alpha in Preeclampsia [PDF]

Applied Medical Informatics, 2008
Introduction: Preeclampsia is an exacerbation of a generalized inflammatory response, physiologically present in the third trimester of pregnancy.Aim: The aim of the study consists in the evaluation of proinflammatory cytokine TNF-α in the context of ...
Dan MIHU, Nicolae COSTIN, Ligia Daniela BLAGA, Septimiu CIUCHINĂ, Raluca Bogdana POP   +4 more
doaj  

A highly sensitive SERS quenching nanosensor for the determination of tumor necrosis factor alpha in blood

, 2020
Tumor necrosis factor alpha (TNF-α) is a cytokine that plays a critical role in medical conditions such cardiovascular diseases, rheumatoid arthritis, inflammatory bowel disease, Alzheimer’s and cancer.
Izake, Emad L, Sonar, Prashant, Gholami, Mahnaz D, Ayoko, Godwin A   +3 more
core   +1 more source

Tumor Necrosis Factor Alpha: Implications of Anesthesia on Cancers

Cancers, 2023
Cancer remains a major public health issue and a leading cause of death worldwide. Despite advancements in chemotherapy, radiation therapy, and immunotherapy, surgery is the mainstay of cancer treatment for solid tumors. However, tumor cells are known to disseminate into the vascular and lymphatic systems during surgical manipulation.
Wei-Cheng Tseng, Hou-Chuan Lai, Yi-Hsuan Huang, Shun-Ming Chan, Zhi-Fu Wu   +4 more
openaire   +2 more sources

Single-cell multi-omics reveals the TNF-α activation threshold for Classical Monocytes by studying healthy donors and rheumatoid arthritis patients

Frontiers in Immunology
IntroductionTumor Necrosis Factor Alpha is a known pro-inflammatory cytokine that plays a key role in the pathogenesis of rheumatoid arthritis. Anti-cytokine therapies targeting Tumor Necrosis Factor Alpha have greatly succeeded in treating rheumatoid ...
Roman Perik-Zavodskii, Roman Perik-Zavodskii, Olga Perik-Zavodskaia, Saleh Alrhmoun, Saleh Alrhmoun, Julia Lopatnikova, Julia Lopatnikova, Alina Alshevskaya, Julia Zhukova, Julia Zhukova, Julia Shevchenko, Julia Shevchenko, Nadezhda Shkaruba, Natalia Sivitskaya, Shakir Suleimanov, Elizaveta Sheveleva, Kirill Nazarov, Fedor Kireev, Fedor Kireev, Alexey Sizikov, Elena Golikova, Sergey Sennikov, Sergey Sennikov   +22 more
doaj   +1 more source

Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes.

, 1990
Progressive destruction of the insulin-producing beta cells in nonobese diabetic mice is observed after infiltration of the pancreas with lymphocytes [Makino, S., Kunimoto, K., Muraoka, Y., Mizushima, Y., Katagiri, K. & Tochino, Y. (1980) Exp.
MacDonald, H R, Weissman, I L, Mueller, C, Held, W, Mueller, C., Hess, M W, MacDonald, H.R., Held, W., Weissman, I.L., Hess, M.W.   +9 more
core   +1 more source