Results 241 to 250 of about 501,207 (351)

TREM2‐Mediated Cholesterol Efflux in Macrophages Inhibits Anti‐Tumor Immunity via Limitation of CD4+ T and NK Cells

Advanced Science, EarlyView.
Impaired anti‐tumor immunity is mediated by TREM2 + macrophages in non‐small cell lung cancer. TREM2 + macrophages prevent anti‐tumor immunity depending on the limitation of CD4 + T and NK cells. TREM2 promotes cholesterol efflux via ABCA1 to limit the production of CX3CL1 in macrophages.
Yunhan Wang, Weina Yu, Xinxin Wang, Qitai Zhao, Qingyang Lei, Aitian Li, Shasha Liu, Tian Wang, Li Yang, Yi Zhang   +9 more
wiley   +1 more source

Prospective Associations of Serum Tumor Necrosis Factor-Alpha and Employment on Suicidal Behaviors Over 1 Year in Depressive Patients Receiving Psychopharmacotherapy. [PDF]

Psychiatry Investig
Kim HY, Kim JW, Kang HJ, Lee JY, Kim SW, Shin IS, Chun BJ, Kim MG, Kim JM.   +8 more
europepmc   +1 more source

Tumor necrosis factor-alpha and its receptors in epithelial ovarian cancer.

, 2010
Bożena Dobrzycka, S Terlikowski, Magdalena Garbowicz, Wiesława Niklińska, Piotr Bernaczyk, Jacek Nikliński, Maciej Kinalski, L Chyczewski   +7 more
openalex   +2 more sources

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

Advanced Science, EarlyView.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan, Senlin Li, Shuai Liu, Hong Zhou, Yue Xu, Wenhui Li, Mengxuan Wang, Mengheng Wang, Mengzhu Zheng, Wenxi Shi, Xin Li, Yiting Feng, Ming Xiang   +12 more
wiley   +1 more source

Successful Treatment of Refractory Mucocutaneous Behçet's Disease With Gastrointestinal Involvement Using Anti-tumor Necrosis Factor-Alpha (Anti-TNF-α) Therapy. [PDF]

Cureus
Elfatih Mohamed M, Mazin Al-Issa R, Ahmed H, Emad Al-Zaidy A, Elbadawi F.   +4 more
europepmc   +1 more source

Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat.

Proceedings of the National Academy of Sciences of the United States of America, 1989
E. Duh, W. Maury, T. Folks, A. Fauci, A. Rabson   +4 more
semanticscholar   +1 more source

Midkine‐Mediated Microglia Activation after Renal Injury Promotes Cognitive Impairment Following Ischemic Renal Injury

Advanced Science, EarlyView.
The mechanism of secondary cognitive impairment following AKI. When renal ischemic injury progresses to fibrosis, renal fibroblasts and damaged tubular cells secrete MDK, which circulates through the bloodstream, crosses the damaged BBB, and accumulates in the hippocampus tissue (an area crucial for learning and memory).
Li Lu, Bixiao Liu, Yu Yang, Tao Meng, Yuanyuan Chang, Yao Peng, Jia Guo, Zhuqing Wang, Hongqian Guo, Liuhua Zhou, Xiaozhi Zhao   +10 more
wiley   +1 more source

The Impact of Two Cordless Retraction Materials on Inflammatory Biomarkers Interleukin-1 Beta and Tumor Necrosis Factor-Alpha in Gingival Crevicular Fluid: An In-Vivo Study. [PDF]

Cureus
Pidaparthi S, Krishna Kishore K, Surapaneni H, Madhavarapu NP, Sultana N, Adavikatla S, Gupta S.   +6 more
europepmc   +1 more source

Membrane-derived second messenger regulates x-ray-mediated tumor necrosis factor alpha gene induction.

, 1994
Dennis E. Hallahan, S. Virudachalam, J Kuchibhotla, Donald Küfe, R.R. Weichselbaum   +4 more
openalex   +2 more sources

Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone.

Proceedings of the National Academy of Sciences of the United States of America, 1989
T. Folks, K. Clouse, J. Justement, A. B. Rabson, E. Duh, J. Kehrl, A. Fauci   +6 more
semanticscholar   +1 more source