Results 41 to 50 of about 648,894 (406)

Partial purification of a serum factor that causes necrosis of tumors. [PDF]

open access: yes, 1976
Tumor necrosis can be induced in transplanted mouse methylcholanthrene-induced sarcoma by a tumor necrosis factor in the serum of mice infected with bacillus Calmette-Guérin and given bacterial endotoxin.
A. Dobrjansky   +6 more
core   +2 more sources

Eicosanoids and tumor necrosis factor-alpha in the kidney [PDF]

open access: yesProstaglandins & Other Lipid Mediators, 2012
The thick ascending limb of Henle's loop (TAL) is capable of metabolizing arachidonic acid (AA) by cytochrome P450 (CYP450) and cyclooxygenase (COX) pathways and has been identified as a nephron segment that contributes to salt-sensitive hypertension. Previous studies demonstrated a prominent role for CYP450-dependent metabolism of AA to products that ...
Ferreri, Nicholas R.   +4 more
openaire   +5 more sources

ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENT

open access: yesRomanian Journal of Oral Rehabilitation, 2022
Introduction. The studies regarding the involvement of TNF-alpha together with other pro-inflammatory cytokines in the occurrence and progression of peri-implantitis is of particular importance in the perspective of making an early diagnosis regarding ...
Marcel-Lucian Dobresu   +7 more
doaj  

Peptidoglycan and Bacterial DNA Induce Inflammation and Coagulation Markers in Synergy [PDF]

open access: yes, 2005
Bacterial compounds signal the presence of foreign pathogens in the innate immune system. These microbial components are key players in infectious diseases and implicate toll-like receptors in the activation of inflammation and coagulation. Nevertheless,
Amoureux, Marie-Claude   +3 more
core   +4 more sources

Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis.

open access: yesArthritis & Rheumatism, 1998
OBJECTIVE To evaluate the efficacy, pharmacokinetics, immunogenicity, and safety of multiple infusions of a chimeric monoclonal anti-tumor necrosis factor alpha antibody (cA2) (infliximab; Remicade, Centocor, Malvern, PA) given alone or in combination ...
R. Maini   +11 more
semanticscholar   +1 more source

Tumor Necrosis Factor Alpha (TNF-α), Nuclear Factor of kappa B (NF-kB) p65 and Calcineurin Expression play a role in the regulation of muscle regeneration process through aerobic exercise in HIV patients [PDF]

open access: yes, 2017
Background: Human Immunodeficiency Virus infection is a chronic disease with inflammatory conditions and experience progressive muscle wasting with increasing of tumor necrosis factor alpha.
Alex Pangkahila   +5 more
core   +4 more sources

The assessment of TNF-α interaction with oligopeptide Trp-Asn-Trp-Val in vitro [PDF]

open access: yesВестник Витебского государственного медицинского университета, 2022
The hyperproduction of TNF-α in the human body is a pathogenetic factor of many diseases development. The widespread clinical use of anticytokine drugs based on antibodies has a number of limitations.
T.V. Ryabtseva   +2 more
doaj   +1 more source

Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]

open access: yes, 2012
BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza   +4 more
core   +1 more source

Tumor Necrosis Factor Alpha-Mediated Asthma? [PDF]

open access: yesInternational Archives of Allergy and Immunology, 2012
Thus the pathophysiology of allergic asthma is traditionally explained by mast celland/or Th2 cell-mediated airway inflammation, which is a manifestation of the acquired immune response. On the other hand, recent studies have identified various other important molecules associated with phenotypes of asthma, including tumor necrosis factor (TNF)[2, 3] ,
openaire   +3 more sources

Influence of ?S-globin haplotypes and hydroxyurea on tumor necrosis factor-alpha levels in sickle cell anemia

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2014
Background: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha.
Marília Rocha Laurentino   +5 more
doaj   +1 more source

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