Results 41 to 50 of about 693,338 (390)

The assessment of TNF-α interaction with oligopeptide Trp-Asn-Trp-Val in vitro [PDF]

open access: yesВестник Витебского государственного медицинского университета, 2022
The hyperproduction of TNF-α in the human body is a pathogenetic factor of many diseases development. The widespread clinical use of anticytokine drugs based on antibodies has a number of limitations.
T.V. Ryabtseva   +2 more
doaj   +1 more source

Understanding the immunopathogenic bases and the clinical approach of the periodic syndrome associated with the tumor necrosis receptor, TRAPS

open access: yesIatreia, 2018
Tumor necrosis factor receptor periodic syndrome (TRAPS) is characterized by episodes of fever of more than 10 days of duration, migratory myalgias, pseudocellulitis, abdominal pain and bipalpebral edema.
Moreno Zuluaga, Catalina   +1 more
doaj   +1 more source

Tumor Necrosis Factor Alpha: Implications of Anesthesia on Cancers

open access: yesCancers, 2023
Cancer remains a major public health issue and a leading cause of death worldwide. Despite advancements in chemotherapy, radiation therapy, and immunotherapy, surgery is the mainstay of cancer treatment for solid tumors. However, tumor cells are known to disseminate into the vascular and lymphatic systems during surgical manipulation.
Wei-Cheng Tseng   +4 more
openaire   +2 more sources

Differences in reactivation of tuberculosis induced from anti-tnf treatments are based on bioavailability in granulomatous tissue [PDF]

open access: yes, 2007
The immune response to Mycobacterium tuberculosis (Mtb) infection is complex. Experimental evidence has revealed that tumor necrosis factor (TNF) plays a major role in host defense against Mtb in both active and latent phases of infection.
Denise E Kirschner   +7 more
core   +3 more sources

Recombinant Tumor Necrosis Factor-Alpha

open access: yesDefinitions, 2020
A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine tumor necrosis factor-alpha with antineoplastic properties.

semanticscholar   +1 more source

Viewpoint on handling anti-TNF failure in psoriasis [PDF]

open access: yes, 2013
An association among the occurrence of antidrug antibodies (ADAs), diminished trough serum drug levels (TSDLs) and non-response or loss of response has been described for several tumor necrosis factor alpha (TNF) blocking agents in a variety of diseases,
BRACKE, STEFANIE, Lambert, Jo
core   +1 more source

Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice [PDF]

open access: yes, 2016
Objective: Explore aorta B cell immunity in aged ApoE-/- mice. Approach and Results: Transcript maps, FACS, immunofluorescence analyses, cell transfers, and Ig-ELISPOT assays showed multi-layered atherosclerosis B cell responses in artery tertiary ...
Andreas J.R. Habenicht   +13 more
core   +1 more source

Tumor Necrosis Factor Alpha In Preeclampsia

open access: yes, 2013
Pre-eclampsia is one of the most frequent complications of pregnancy, however, little is known about its aetiology. Insufficient adaptation of the decidual and intramyometrial portions of the spiral arterioles in preeclampsia results in reduced utero-placental blood flow, leading to local placental hypoxia.
Fozia A Patigaroo   +3 more
openaire   +2 more sources

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes

open access: yesJournal of Experimental Medicine, 1991
Thalidomide selectively inhibits the production of human monocyte tumor necrosis factor alpha (TNF-alpha) when these cells are triggered with lipopolysaccharide and other agonists in culture. 40% inhibition occurs at the clinically achievable dose of the
E. Sampaio   +4 more
semanticscholar   +1 more source

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]

open access: yes, 2018
BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.

core   +2 more sources

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