Partial purification of a serum factor that causes necrosis of tumors. [PDF]
Tumor necrosis can be induced in transplanted mouse methylcholanthrene-induced sarcoma by a tumor necrosis factor in the serum of mice infected with bacillus Calmette-Guérin and given bacterial endotoxin.
A. Dobrjansky+6 more
core +2 more sources
Eicosanoids and tumor necrosis factor-alpha in the kidney [PDF]
The thick ascending limb of Henle's loop (TAL) is capable of metabolizing arachidonic acid (AA) by cytochrome P450 (CYP450) and cyclooxygenase (COX) pathways and has been identified as a nephron segment that contributes to salt-sensitive hypertension. Previous studies demonstrated a prominent role for CYP450-dependent metabolism of AA to products that ...
Ferreri, Nicholas R.+4 more
openaire +5 more sources
ALPHA TUMOR NECROSIS – AS PREDICTIVE FACTOR IN DENTAL IMPLANT MANAGEMENT
Introduction. The studies regarding the involvement of TNF-alpha together with other pro-inflammatory cytokines in the occurrence and progression of peri-implantitis is of particular importance in the perspective of making an early diagnosis regarding ...
Marcel-Lucian Dobresu+7 more
doaj
Peptidoglycan and Bacterial DNA Induce Inflammation and Coagulation Markers in Synergy [PDF]
Bacterial compounds signal the presence of foreign pathogens in the innate immune system. These microbial components are key players in infectious diseases and implicate toll-like receptors in the activation of inflammation and coagulation. Nevertheless,
Amoureux, Marie-Claude+3 more
core +4 more sources
OBJECTIVE To evaluate the efficacy, pharmacokinetics, immunogenicity, and safety of multiple infusions of a chimeric monoclonal anti-tumor necrosis factor alpha antibody (cA2) (infliximab; Remicade, Centocor, Malvern, PA) given alone or in combination ...
R. Maini+11 more
semanticscholar +1 more source
Tumor Necrosis Factor Alpha (TNF-α), Nuclear Factor of kappa B (NF-kB) p65 and Calcineurin Expression play a role in the regulation of muscle regeneration process through aerobic exercise in HIV patients [PDF]
Background: Human Immunodeficiency Virus infection is a chronic disease with inflammatory conditions and experience progressive muscle wasting with increasing of tumor necrosis factor alpha.
Alex Pangkahila+5 more
core +4 more sources
The assessment of TNF-α interaction with oligopeptide Trp-Asn-Trp-Val in vitro [PDF]
The hyperproduction of TNF-α in the human body is a pathogenetic factor of many diseases development. The widespread clinical use of anticytokine drugs based on antibodies has a number of limitations.
T.V. Ryabtseva+2 more
doaj +1 more source
Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]
BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza+4 more
core +1 more source
Tumor Necrosis Factor Alpha-Mediated Asthma? [PDF]
Thus the pathophysiology of allergic asthma is traditionally explained by mast celland/or Th2 cell-mediated airway inflammation, which is a manifestation of the acquired immune response. On the other hand, recent studies have identified various other important molecules associated with phenotypes of asthma, including tumor necrosis factor (TNF)[2, 3] ,
openaire +3 more sources
Background: Sickle cell anemia is a chronic inflammatory disease characterized by an increased production of proinflammatory cytokines including tumor necrosis factor-alpha.
Marília Rocha Laurentino+5 more
doaj +1 more source