Results 71 to 80 of about 693,338 (390)

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Psoriasiform Sarcoidosis Presenting in Pregnancy and Treatment Considerations [PDF]

, 2018
Cutaneous sarcoidosis is a common presentation for patients with sarcoidosis. Rarely, patients can present with psoriasiform lesions mimicking chronic plaque psoriasis. Here, we present a case of psoriasiform sarcoidosis in a pregnant patient.
Albornoz, Christian A., Keller, Matthew, Wang, Jordan   +2 more
core   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Expression of periostin in the epithelium of cholesteatoma with different degrees of ossicular chain destruction and its clinical value in predicting postoperative hearing recovery

BioMedical Engineering OnLine
Objectives To explore the expression of periostin in the epithelium of cholesteatoma with different destruction degrees of the ossicular chain and its clinical value in predicting postoperative hearing recovery.
Cuncun Xie, Xiaodong Jia, Shaoguang Ding, Xiaoli Ding, Guangke Wang, Hongjian Liu   +5 more
doaj   +1 more source

Serum cholesterol levels in neutropenic patients with fever [PDF]

, 2002
Hypocholesterolemia, which often accompanies infectious diseases has been suggested to serve as a prognostic marker in hospitalized patients. Even though patients with chemotherapyinduced leukopenia are at high risk of infection and mortality, only ...
Alvarez C, Bodey GP, Ettinger WH, Ettinger WH, Ettinger WH, Hermus R, Jacobs D, Pacelli F, Steinmetz HT, van Gameren MM, Werner M   +10 more
core   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Histone deacetylase inhibitor givinostat has ameliorative effect in the colitis model

Acta Cirúrgica Brasileira, 2022
Purpose: To investigate the effect of givinostat treatment in acetic acid-induced ulcerative colitis model in rats. Methods: Thirty male Wistar albino rats were used. Rats were randomly divided into three equal groups, and colitis was induced on 20 rats
Cengiz Dibekoğlu, Oytun Erbaş
doaj   +1 more source

Tumor necrosis factor-alpha and the cytokine network in psoriasis [PDF]

Anais Brasileiros de Dermatologia, 2012
New molecular methods of research have greatly expanded the knowledge about the role of cytokines in several diseases, including psoriasis. The work orchestrated by these peptides is essential for the communication between resident inflammatory cells (keratinocytes and endothelial cells) and infiltrating cells (neutrophils, lymphocytes, Langerhans ...
Cristiane Chaves Nascentes Machado, Arles Martins Brotas, Eduardo Henrique Jorge Lago, Jose Marcos T. Cunha, Sueli Carneiro, Sueli Carneiro   +5 more
openaire   +5 more sources

Stromagenesis and cancer‐associated fibroblast heterogeneity in primary tumors and metastasis: focus in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
Cancer‐associated fibroblasts (CAFs) play different roles in NSCLC progression and metastasis. Their heterogeneous origins and phenotypes shape the tumor microenvironment and influence metastatic spread. This review highlights NSCLC CAF subtypes, their potential cellular sources, and their differential distribution across primary tumors and distant ...
Alejandro Bernardo, Natalia Díaz‐Valdivia, Patricia Fernández‐Nogueira, Jordi Alcaraz   +3 more
wiley   +1 more source

Curcumin Oral Gel and its Relation to Salivary Tumor Necrosis Factor-Alpha and Interleukin-6 that Treated Oral Mucositis in Head and Neck Cancer Patients Undergoing Concurrent Chemoradiation

Diyala Journal of Medicine
Background: Curcumin oral gel is one example of a traditional herbal medication, it has shown potential in several pharmaceutical uses. Oral mucositis is commonly prevent and treat using magic solution, a mouthwash that contains a combination of ...
Rouaa S. Farhan, Fawaz D. Al-Aswad
doaj   +1 more source