Results 31 to 40 of about 967,686 (297)

miR-29a suppresses MCF-7 cell growth by downregulating tumor necrosis factor receptor 1

open access: yesTumor Biology, 2017
Tumor necrosis factor receptor 1 is the main receptor mediating many tumor necrosis factor-alpha–induced cellular events. Some studies have shown that tumor necrosis factor receptor 1 promotes tumorigenesis by activating nuclear factor-kappa B signaling ...
Yiling Zhao   +7 more
doaj   +1 more source

Role of tumour necrosis factor gene polymorphisms (-308 and -238) in breast cancer susceptibility and severity [PDF]

open access: yes, 2004
Introduction Genetic polymorphisms in the promoter region of the tumour necrosis factor (TNF) gene can regulate gene expression and have been associated with inflammatory and malignant conditions. We have investigated two polymorphisms in the promoter
Azmy, I.A.F.   +6 more
core   +2 more sources

Modulation of tumor necrosis factor by microbial pathogens. [PDF]

open access: yesPLoS Pathogens, 2006
In response to invasion by microbial pathogens, host defense mechanisms get activated by both the innate and adaptive arms of the immune responses. TNF (tumor necrosis factor) is a potent proinflammatory cytokine expressed by activated macrophages and ...
Masmudur M Rahman, Grant McFadden
doaj   +2 more sources

Reduction of circulating cholesterol and apolipoprotein levels during sepsis [PDF]

open access: yes, 1999
Sepsis with multiple organ failure is frequently associated with a substantial decrease of cholesterol levels. This decrease of cholesterol is strongly associated with mortality suggesting a direct relation between inflammatory conditions and altered ...
Alvarez C   +27 more
core   +1 more source

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]

open access: yes, 2018
BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.

core   +2 more sources

Impaired interferon-γ responses, increased interleukin-17 expression, and a tumor necrosis factor–α transcriptional program in invasive aspergillosis [PDF]

open access: yes, 2009
This article is available open access through the publisher’s website. Copyright @ 2009 Oxford University Press.Background - Invasive aspergillosis (IA) is the most common cause of death associated with fungal infection in the developed world ...
Armstrong-James, DP   +7 more
core   +1 more source

The effect of ulipristal acetate on tumor necrosis factor α, insulin-like growth factor 1, and plasminogen activator inhibitor-1 serum levels in patients with symptomatic uterine fibroids

open access: yesArchives of Medical Science, 2020
Introduction Uterine fibroids (UFs) are benign tumors of the female reproductive system originating from the smooth muscle of the uterus. Currently, progesterone is known to play a key role in the differentiation of the myometrial tissue to form UFs and ...
Michał Ciebiera   +7 more
doaj   +1 more source

Hubungan Kadar Tumor Necrosis Factor – Α Dengan Densitas Plasmodium Pada Penderita Malaria [PDF]

open access: yes, 2014
: Malaria is a parasitic infection that attacks the erythrocytes. This disease remains a global health problem, especially in developing countries in the tropics and subtropics. Symptomatic malaria infection include fever, chills, anemia and splenomegaly.
Bernadus, J. B. (Janno)   +2 more
core  

Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea. [PDF]

open access: yes, 2016
Three new diterpenes, uprolide N (1), uprolide O (2), uprolide P (3) and a known one, dolabellane (4), were isolated from the CH₂Cl₂-MeOH extract of the gorgonian octocoral Eunicea succinea, collected from Bocas del Toro, on the Caribbean coast of Panama.
Fernandez, Patricia L   +7 more
core   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

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