Results 231 to 240 of about 729,544 (396)

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury

Advanced Science, EarlyView.
By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li, Jinlin Liao, Yuxi Zhang, Zifu Yao, Junxin Huang, Kejia Wu, Lu Li, Yiling Peng, Haili Zhu, Xue Hong, Xi Liu, Lili Zhou, Fan Fan Hou, Haiyan Fu, Youhua Liu   +14 more
wiley   +1 more source

Pigmented Purpuric Dermatosis Following Tumor Necrosis Factor-Alpha Inhibitor Therapy: A Case Report. [PDF]

Arch Rheumatol
Beke SK, Kaplan H, Cengiz G, Deniz K, Kartal D.   +4 more
europepmc   +1 more source

Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.

Journal of Clinical Investigation, 1994
G. Hotamisligil, A. Budavari, David L. Murray, B. Spiegelman   +3 more
semanticscholar   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source

Tumor Necrosis Factor Alpha(α) [PDF]

, 2013
openaire   +2 more sources

Analysis of the Expression Patterns of Tumor Necrosis Factor Alpha Signaling Pathways and Regulatory MicroRNAs in Astrocytic Tumors. [PDF]

Int J Mol Sci
Skóra K, Strojny D, Sobański D, Staszkiewicz R, Gogol P, Miller M, Grabarek BO.   +6 more
europepmc   +1 more source

Tumor necrosis factor (TNF)-alpha activates c-raf-1 kinase via the p55 TNF receptor engaging neutral sphingomyelinase.

, 1995
Claus Belka, Katja Wiegmann, Dieter Adam, Robert E. Holland, M. Neuloh, F. Herrmann, Martin Krönke, M. A. Brach   +7 more
openalex   +2 more sources

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

Proceedings of the National Academy of Sciences of the United States of America, 1993
C. Tripp, S. Wolf, E. Unanue
semanticscholar   +1 more source

Stimuli‐Responsive CuFeTe2 Nanosheets for Amplified Cuproptosis/Ferroptosis in Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Dual‐stimuli‐responsive CuFeTe2 nanosheets (CFT) induce cuproptosis/ferroptosis via TME‐responsive Fe2⁺/Cu2⁺ release and NIR‐II photothermal effects, amplifying ROS and depleting HSP70/ATP to trigger ICD and immune activation, while ensuring biocompatible renal clearance for TNBC therapy.
Molin Liu, Jian Zheng, Mengqi Yu, Qirui Wang, Yi Yuan, Nannan Shao, Xiaoliang Yang, Tianxi Shen, Li Wang, Aiyun Li, Rui Liu, Jimin Cao, Xi Liu, Fangfang Cao, Yanlin Feng   +14 more
wiley   +1 more source

Assessing the Significance of Interleukin-6, Interleukin-10, and Tumor Necrosis Factor-Alpha in Peri-Implantitis Development: A Biomarker Study. [PDF]

Cureus
Bhukal S, Malik R, Begum R, Adapala K, Killamsetty M, Arora P, Gupta S.   +6 more
europepmc   +1 more source