Results 251 to 260 of about 729,544 (396)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Tumor Necrosis Factor-Alpha (TNF- α) and Antiviral Activities of Artemisia SPP. Extracts on SARS-COV2. [PDF]

Rwanda J Med Health Sci
Banjo TA, Binuyo MO, Siyanbola W, Ashidi JS, Otuonye NM, Mutiu WB, Akinola SA, Akindele RA, Adeyemo RO, Fatungase OM, Kageruka H, Oparaugo CT, Oladoja FA, Adedeji AA, Afocha EE, Kazim LS.   +15 more
europepmc   +1 more source

Autocrine tumor necrosis factor (TNF) and lymphotoxin (LT) alpha differentially modulate cellular sensitivity to TNF/LT-alpha cytotoxicity in L929 cells. [PDF]

, 1998
Akashi, Androlewicz, Black, Browning, Browning, Browning, Chaturvedi, Chiacchia, Crowe, De Togni, Decoster, Engelmann, English, Espevik, Espevik, Estrov, Fiers, Fransen, Hass, Huylebroeck, Koni, Kriegler, Krönke, Lewis, Lucas, Mackay, Mantovani, Matthews, Mellow, Moss, Müller, Nedospasov, Olsen, Paul, Southern, Spies, Steer, Sung, Tada, Tang, Tartaglia, Tartaglia, Tartaglia, Tartaglia, Vandenabeele, Vanhaesebroeck, Vanhaesebroeck, Vercammen, Vilček   +48 more
core   +2 more sources

Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo.

Proceedings of the National Academy of Sciences of the United States of America, 1992
K. Zee, T. Kohno, E. Fischer, C. S. Rock, L. Moldawer, S. Lowry   +5 more
semanticscholar   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

Tumor necrosis factor alpha-induced protein 3: A key biomarker for response to ursodeoxycholic acid in primary biliary cholangitis. [PDF]

World J Hepatol
Zang B, Li JX, Liu QX, Yao Y, Li H, Wang Y, Wang JG, Yang YF, Liang RW, Xin XR, Liu B.   +10 more
europepmc   +1 more source

2'-5' oligo-A-synthetase activity in bovine peripheral blood leukocytes and alveolar macrophages exposed to recombinant interferons and tumor necrosis factor-alpha.

, 1989
H. Bielefeldt Ohmann, Marli Matiko Anraku de Campos, Philip Griebel, Lorne A. Babiuk   +3 more
openalex   +1 more source

Effects of RP 55778, a tumor necrosis factor alpha synthesis inhibitor, on antiviral activity of dideoxynucleosides [PDF]

, 1997
Pascal Clayette, N Dereuddre-Bosquet, Marc Martín, Philippe Frétier, Dominique Dormont   +4 more
openalex   +1 more source

Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat.

Journal of Clinical Investigation, 1990
L. Colletti, D. Remick, G. Burtch, S. Kunkel, R. Strieter, D. Campbell   +5 more
semanticscholar   +1 more source

TREM2‐Mediated Cholesterol Efflux in Macrophages Inhibits Anti‐Tumor Immunity via Limitation of CD4+ T and NK Cells

Advanced Science, EarlyView.
Impaired anti‐tumor immunity is mediated by TREM2 + macrophages in non‐small cell lung cancer. TREM2 + macrophages prevent anti‐tumor immunity depending on the limitation of CD4 + T and NK cells. TREM2 promotes cholesterol efflux via ABCA1 to limit the production of CX3CL1 in macrophages.
Yunhan Wang, Weina Yu, Xinxin Wang, Qitai Zhao, Qingyang Lei, Aitian Li, Shasha Liu, Tian Wang, Li Yang, Yi Zhang   +9 more
wiley   +1 more source