Results 311 to 320 of about 510,377 (352)

Circulating bioactive tumor necrosis factor-α, tumor necrosis factor-α receptors, fibronectin, and tumor necrosis factor-α inducible cell adhesion molecule VCAM-1 in uncomplicated pregnancy

American Journal of Obstetrics and Gynecology, 1997
Our goal was to assess in a longitudinal study of uncomplicated pregnancy the course of maternal plasma concentrations of the bioactive cytokine tumor necrosis factor-alpha, the soluble tumor necrosis factor-alpha receptors sTNFRI and sTNFRII, the soluble cell adhesion molecule sVCAM-1, and circulating fibronectin.Blood was collected from 22 healthy ...
Beckmann, Ilse, Visser, Willy, Struijk, PC (Pieter), van Dooren, M, Glavimans, J, Wallenburg,   +5 more
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Tumor necrosis factor-α converting enzyme

The International Journal of Biochemistry & Cell Biology, 2002
Tumor necrosis factor-alpha converting enzyme (TACE/ADAM17/CD156q) is a member of the 'A Disintegrin And Metalloprotease', or ADAM, family. It is a multi-domain, type I transmembrane protein that includes an extracellular zinc-dependent protease domain.
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Tumor necrosis factor alpha disrupts tight junction assembly

Journal of Surgical Research, 2004
We have previously shown an increase in intestinal permeability and a corresponding decrease in the expression of tight junction (TJ) proteins in the in testines of patients with Crohn's disease (CD). Tumor necrosis factor-alpha (TNFalpha) has been implicated in the inflammatory process of CD and its suppression has therapeutic benefit. ZO-1, occludin,
Lisa S, Poritz, Kristian I, Garver, Anna F, Tilberg, Walter A, Koltun   +3 more
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Tuberculosis Infections and Tumor Necrosis Factor Alpha Antagonists

American Journal of Therapeutics, 2013
The treatment of rheumatologic diseases with tumor necrosis factor-alpha antagonists has become common practice. Studies have demonstrated an increased risk of active tuberculosis with use of tumor necrosis factor-alpha antagonists. We aim to better define the risk of tuberculosis infection associated with tumor necrosis factor-alpha antagonists and to
Justin, Gan, Augustine M, Manadan, Winston, Sequiera, Joel A, Block   +3 more
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Role of tumor necrosis factor alpha in asthma

Immunology and Allergy Clinics of North America, 2004
Asthma is a heterogeneous disease in which various cytokines orchestrate airway inflammation. Tumor necrosis alpha (TNF-alpha) is a proinflammatory cytokine that has been implicated in the modulation of inflammation in various diseases, including asthma. Although TNF-alpha blocking strategies have been an effective therapeutic modality in diseases such
Babu, K. Suresh, Davies, Donna E., Holgate, Stephen T.   +2 more
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[Tumor necrosis factor alpha. Biological aspects].

Giornale italiano di chemioterapia, 1989
Human Tumor Necrosis Factor-alpha (TNF-alpha) is a multifaceted cytokine mainly produced by activated monocytes or macrophages. Several recent studies have shown that TNF-alpha can exert a variety of in vitro and in vivo effects including: modulation of normal and malignant haemopoiesis, antineoplastic activity, activation of neutrophils, induction of ...
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Priapism after tumor necrosis factor alpha inhibitor use

Clinical Rheumatology, 2015
We present a possible important association of tumor necrosis factor-alpha inhibition (TNFa-i) and erectile function in a male patient with rheumatoid arthritis (RA). Long-standing, untreated RA may result in significant physical limitation and disability, however often overlooked is the association between RA and erectile and sexual dysfunction ...
Adam J, Kreitenberg, Elizabeth C, Ortiz, Daniel G, Arkfeld   +2 more
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[Tumor necrosis factor-alpha (cachectin)].

Revista clinica espanola, 1989
Tumor necrosis factor (TNF) is liberated by macrophages in response to infection. It has different biological effects, namely cytotoxicity on some tumor cell lines, anorexia, hyperlipidemia, and decreases in protein synthesis. It favors immunological responses and produces necrosis of certain tumors.
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Cardiodepression by tumor necrosis factor-alpha.

European cytokine network, 1999
Cardiodepressant effects of tumor necrosis factor-alpha (TNF-alpha have been documented in numerous experimental settings in vivo and in vitro. In vivo administration of TNF-alpha mimicks the cardiovascular pattern of sepsis including septic cardiomyopathy.
U, Müller-Werdan, H, Engelmann, K, Werdan   +2 more
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Bioassay for Tumor Necrosis Factors-alpha and -beta

Molecular Biotechnology, 2000
Tumor necrosis factor (TNF) is a central cytokine in the pathogenesis of septic shock and other inflammatory states. Assay by immunoassay is convenient, but, because of circulating soluble receptors, does not accurately reflect biological activity of the cytokine.
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