Role of tumor necrosis factor receptor superfamily member 19 in cancer: Diverse functions and therapeutic potential (Review). [PDF]
Xu M +7 more
europepmc +1 more source
Unveiling the therapeutic mechanisms of Eucommia ulmoides-Achyranthes bidentata in osteoporosis: A network pharmacology and molecular docking study. [PDF]
Li K +5 more
europepmc +1 more source
Advances in tumor necrosis factor-α inhibitors for the treatment of juvenile idiopathic arthritis-associated uveitis. [PDF]
Ding H, Fan S, Ma X.
europepmc +1 more source
The ubiquitin-editing enzyme A20 (TNFAIP3): mechanisms of activation, biological function, diseases and therapeutic targets. [PDF]
Hu J, Liu X, Zhou W, Zhong B, Liu F.
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Regulation and dysregulation of tumor necrosis factor receptor-1.
Cytokine & Growth Factor Reviews, 2014TNF is an essential regulator of the immune system. Dysregulation of TNF plays a role in the pathology of many auto-immune diseases. TNF-blocking agents have proven successful in the treatment of such diseases. Development of novel, safer or more effective drugs requires a deeper understanding of the regulation of the pro-inflammatory activities of TNF
L. Puimège +2 more
semanticscholar +3 more sources
Tumor necrosis factor (TNF) is a proinflammatory cytokine, which is involved in physiological and pathological processes and has been found to be crucial for pain development.
Tania Del Rivero +4 more
semanticscholar +1 more source
Solution structure of the tumor necrosis factor receptor-1 death domain
Journal of Molecular Biology, 2001Tumor necrosis factor receptor-1 death domain (TNFR-1 DD) is the intracellular functional domain responsible for the receptor signaling activities. The solution structure of the R347K mutant of TNFR-1 DD was solved by NMR spectroscopy. A total of 20 structures were calculated by means of hybrid distance geometry-simulated annealing using a total of ...
S F, Sukits +5 more
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Tumor necrosis factor receptor 1 expression and early spontaneous abortion
International Journal of Gynecology & Obstetrics, 2004AbstractObjectivesTo compare tumor necrosis factor receptor 1 (TNFR1) protein expression in women with unexplained early spontaneous abortion (UESA) and normal pregnancy.MethodsIn a prospective study, 62 women with UESA and 60 with normal pregnancy were studied.
X W, Yu, C F, Yan, H, Jin, X, Li
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An expression plasmid encoding the extracellular portion of the human tumor necrosis factor (TNF) type 1 receptor (TNF-R1) was constructed and used to generate a stable cell line secreting soluble TNF-R1 (sTNF-R1). The sTNF-R1 was purified, and its biochemical properties and its interactions with human TNF-alpha were examined.
D, Pennica +7 more
openaire +2 more sources

