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The ubiquitin-editing enzyme A20 (TNFAIP3): mechanisms of activation, biological function, diseases and therapeutic targets. [PDF]
Hu J, Liu X, Zhou W, Zhong B, Liu F.
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Efficacy of S-1 Monotherapy for Salivary Duct Carcinoma With <i>MYC</i> Amplification. [PDF]
Suto H +7 more
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Necroptosis: The Regulation Between EGFR and TNFR in Cancer. [PDF]
Kim JG, Jin W.
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Function and Regulation of Tumor Necrosis Factor Receptor Type 2
Current Medicinal Chemistry, 2004TNF is a major proinflammatory cytokine, which exerts its effects through two different receptors known as TNF-R1 and TNF-R2. Whereas TNF-R1 induced signaling pathways have been very well characterized during the past years, TNF-R2 has been much less well studied.
I, Carpentier, B, Coornaert, R, Beyaert
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Journal of Vascular Research, 2012
The sex hormone estradiol (E<sub>2</sub>) appears to mediate both anti-atherogenic and pro-inflammatory effects in premenopausal women, suggesting a complex immunomodulatory role. Tumor necrosis factor (TNF) is a key pro-inflammatory cytokine involved in the pathogenesis of atherosclerosis and other inflammatory diseases. Alterations at the
Subhadeep, Chakrabarti +1 more
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The sex hormone estradiol (E<sub>2</sub>) appears to mediate both anti-atherogenic and pro-inflammatory effects in premenopausal women, suggesting a complex immunomodulatory role. Tumor necrosis factor (TNF) is a key pro-inflammatory cytokine involved in the pathogenesis of atherosclerosis and other inflammatory diseases. Alterations at the
Subhadeep, Chakrabarti +1 more
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Theriogenology, 2015
Tumor necrosis factor (TNF) alpha likely mediates embryomaternal communication in mammals. In bovine, we have previously found that the uterine fluid of heifers that carried early embryos shows downregulation in the TNF and nuclear factor κB system. In this work, we assessed the expression of TNF and its receptor TNFR2 in the bovine endometrium and ...
E. Correia-Álvarez +11 more
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Tumor necrosis factor (TNF) alpha likely mediates embryomaternal communication in mammals. In bovine, we have previously found that the uterine fluid of heifers that carried early embryos shows downregulation in the TNF and nuclear factor κB system. In this work, we assessed the expression of TNF and its receptor TNFR2 in the bovine endometrium and ...
E. Correia-Álvarez +11 more
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The role of tumor necrosis factor receptor 2 (TNFR2) in EAE
The Journal of Immunology, 2023Abstract Multiple Sclerosis (MS) is a chronic autoimmune disease of the central nervous system which affects over 2 million people worldwide and is the most common neurological disability in young adults. MS is a heterogenous disease characterized by recurrent, remitting and/or progressive neurological deficits, and clinical ...
Maria Montes De Oca Arena +4 more
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Archives of Oral Biology, 2020
Aiming to show that periodontitis (PD) and type 2 diabetes (T2D) are bidirectionally related and potentially linked by inflammatory cytokines, we searched for association between -308 G/A Tumor necrosis factor-alpha (TNFα), +252A/G Lymphotoxin-alpha (LTα), +36A/G Tumor necrosis factor receptor 1 (TNFR1) and +676 T/G tumor necrosis factor receptor 2 ...
Matić Petrović, Sanja +9 more
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Aiming to show that periodontitis (PD) and type 2 diabetes (T2D) are bidirectionally related and potentially linked by inflammatory cytokines, we searched for association between -308 G/A Tumor necrosis factor-alpha (TNFα), +252A/G Lymphotoxin-alpha (LTα), +36A/G Tumor necrosis factor receptor 1 (TNFR1) and +676 T/G tumor necrosis factor receptor 2 ...
Matić Petrović, Sanja +9 more
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Polymorphic analysis of the high‐affinity tumor necrosis factor receptor 2
Tissue Antigens, 1999The tumor necrosis factor receptor 2 (TNF‐RII, CD120b, TNF‐R p75/80) gene has recently been characterised. It is located on chromosome 1p36.2 and consists of 10 exons and 9 introns. A number of biallelic polymorphisms have been found in exons 4, 6, 9 and 10 based on differences between published sequences.
P, Pantelidis +5 more
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Characterization of Porcine Tumor Necrosis Factor Receptor 2: Implications for Xenotransplantation
Transplantation Proceedings, 2007Clinical solid organ xenotransplantation is precluded by the strong immune response that results in rejection of pig xenografts in primate models. Innate immunity seems to play a major role in this process. In particular, tumor necrosis factor (TNF), produced by natural killer cells and macrophages, contributes to xenograft rejection by promoting ...
C, Costa, S R, Casinghino, W L, Fodor
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