Results 261 to 270 of about 589,523 (288)

Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling

The International Journal of Biochemistry & Cell Biology, 2001
Tumor necrosis factor (TNF) is the prototypic member of the TNF ligand family and has a key role in the regulation of inflammatory processes. TNF exerts its functions by interaction with the death domain-containing TNF-receptor 1 (TNF-R1) and the non-death domain-containing TNF-receptor 2 (TNF-R2), both members of a receptor family complementary to the
H, Wajant, P, Scheurich
openaire   +2 more sources

Interferon β-1a Induces Tumor Necrosis Factor Receptor 1 but Decreases Tumor Necrosis Factor Receptor 2 Leukocyte mRNA Levels in Relapsing-Remitting Multiple Sclerosis

Neuroimmunomodulation, 2009
<i>Objective:</i> Members of the tumor necrosis factor (TNF) receptor superfamily play a major role in the pathogenesis of multiple sclerosis. To elucidate the role of TNF receptors, in 53 relapsing-remitting multiple sclerosis patients, we measured the TNF receptor 1 and receptor 2 (TNF-R1 and TNF-R2) mRNA levels in peripheral blood ...
Reinhard, Reuss, Susanne, Pohle, Kerstin, Retzlaff, Jürgen, Hemberger, Patrick, Oschmann   +4 more
openaire   +2 more sources

Determination of Soluble Tumor Necrosis Factor Receptor 2 Produced by Alternative Splicing

2014
Soluble cytokine receptors have proven to be very useful biomarkers in a large variety of diseases, including cancer, infections, and chronic inflammatory diseases. These soluble receptors are produced by proteolytic cleavage or alternative splicing. Several cytokine receptors including tumor necrosis factor receptor 2 (TNFR2) can be generated by both ...
Xavier, Romero, Juan D, Cañete, Pablo, Engel   +2 more
openaire   +2 more sources

Tumor Necrosis Factor Receptor 2–Mediated Tumor Suppression Is Nitric Oxide Dependent and Involves Angiostasis

Cancer Research, 2007
AbstractTumor necrosis factor (TNF) binds to two different receptors. Although most of its functions are attributed to TNF receptor 1 (TNFR1), the independent role of TNFR2 is still largely unknown. Using TNFR single or double knock-out mice, we show here that the expression of TNFR2 alone on host cells was sufficient to suppress the growth of TNF ...
Xueqiang, Zhao, Mariette, Mohaupt, Jing, Jiang, Shubai, Liu, Bing, Li, Zhihai, Qin   +5 more
openaire   +2 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Allelic variation of the type 2 tumor necrosis factor receptor gene

Mammalian Genome, 1994
Powell, EE, Wicker, LS, Peterson, LB, Todd, JA   +3 more
openaire   +3 more sources

Tumor necrosis factor (TNF); tumor necrosis factor receptor 2 (TNFR2)

Science-Business eXchange, 2008
openaire   +1 more source

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Rujul Parikh, Sagar Lonial
exaly  

Tumor Necrosis Factor Receptor-associated Factor 2

2006
openaire   +1 more source

The Tumor Necrosis Factor Ligand and Receptor Families

New England Journal of Medicine, 1996
Flavia Bazzoni
exaly