Results 101 to 110 of about 5,576,002 (348)
Objectives Childhood obesity prevention is a public health priority to reduce the burden of chronic diseases. This study assessed the impact of a capacity-building program designed to enhance school nurses’ competencies in adolescent obesity prevention ...
Radhia Chaieb +6 more
doaj +1 more source
. Modern concepts on carcinogenesis: the value of insufficiency of malignant cell elimination mechanisms in the tumor progression in case of neoplasia at different localizations [PDF]
The article presents the review of contemporary concepts of tumor induction mechanisms applicable for neoplastic transformation, promotion and proliferation.
Chesnokova N.P. +4 more
doaj
SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma [PDF]
Our previous data supported a role for the Stearoyl-CoA desaturase (SCD5) in protection against malignancy, whereby it appears to functionally modify tumor stroma impairing tumor spread.
Bellenghi, Maria +8 more
core +1 more source
Immune Escape during Breast Tumor Progression
Immunotherapy using checkpoint inhibitors is one of the most promising current cancer treatment strategies. However, in breast cancer, its success has been limited to a subset of patients with triple-negative disease, whose durability of observed ...
Carlos R Gil Del Alcazar +2 more
semanticscholar +1 more source
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma. [PDF]
Hepatocellular carcinoma (HCC), is one of the most frequent human cancer and is characterized by a high mortality rate. The aggressiveness appears strictly related to the liver pathological background on which cancer develops.
Amicone, Laura, Marchetti, Alessandra
core +1 more source
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka +7 more
wiley +1 more source
DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs [PDF]
Biomechanical changes in the tumor microenvironment influence tumor progression and metastases. Collagen content and fiber organization within the tumor stroma are major contributors to biomechanical changes (e., tumor stiffness) and correlated with ...
Barcus, Craig E +9 more
core +1 more source
Thyroid status modulates T lymphoma growth via cell cycle regulatory proteins and angiogenesis [PDF]
We have shown in vitro that thyroid hormones (THs) regulate the balance between proliferation and apoptosis of T lymphoma cells. The effects of THs on tumor development have been studied, but the results are still controversial.
Barreiro Arcos, María Laura +10 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source

