Results 71 to 80 of about 5,576,002 (348)

The Emerging Role of Neutrophil Extracellular Traps (NETs) in Tumor Progression and Metastasis

Frontiers in Immunology, 2020
Neutrophil Extracellular Traps (NETs) are net-like structures composed of DNA-histone complexes and proteins released by activated neutrophils. In addition to their key role in the neutrophil innate immune response, NETs are also involved in autoimmune ...
M. Masucci, M. Minopoli, S. Del Vecchio, M. Carriero   +3 more
semanticscholar   +1 more source

Potential Early Risk Biomarkers for Reduced Forced Expiratory Volume in Children Post‐Hematopoietic Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We sought to identify potential early risk biomarkers for lung disease in children post‐allogeneic HCT. Patients with pulmonary function tests 3 months post‐transplant and plasma samples between days 7 and 14 post‐HCT were included. Six of 27 subjects enrolled had reduced forced expiratory volume 1 (FEV1) z scores.
Isabella S. Small, Pi Chun Cheng, April L. Rahrig, Courtney M. Rowan   +3 more
wiley   +1 more source

Personalized Pancreatic Tumor Growth Prediction via Group Learning

, 2017
Tumor growth prediction, a highly challenging task, has long been viewed as a mathematical modeling problem, where the tumor growth pattern is personalized based on imaging and clinical data of a target patient. Though mathematical models yield promising
C Hogea, CC Chang, H Greenspan, I Guyon, J Yao, KCL Wong, M Morris, O Clatz   +7 more
core   +1 more source

Cancer-associated fibroblasts as abettors of tumor progression at the crossroads of EMT and therapy resistance

Molecular Cancer, 2019
In the last decades, the role of the microenvironment in tumor progression and therapeutic outcome has gained increasing attention. Cancer-associated fibroblasts (CAFs) have emerged as key players among stromal cells, owing to their abundance in most ...
M. Fiori, S. Di Franco, L. Villanova, Paola Bianca, G. Stassi, R. De Maria   +5 more
semanticscholar   +1 more source

Personalizing the Pediatric Hematology/Oncology Fellowship: Adapting Training for the Next Generation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein, Melissa J. Rose, Scott Moerdler, Richard Ho   +3 more
wiley   +1 more source

Emerging Treatments Targeting the Tumor Microenvironment for Advanced Chondrosarcoma

Cells
Chondrosarcoma (ChS), a malignant cartilage-producing tumor, is the second most frequently diagnosed osseous sarcoma after osteosarcoma. It represents a very heterogeneous group of malignant chemo- and radiation-resistant neoplasms, accounting for ...
Vincenzo Ingangi, Annarosaria De Chiara, Gerardo Ferrara, Michele Gallo, Antonio Catapano, Flavio Fazioli, Gioconda Di Carluccio, Elisa Peranzoni, Ilaria Marigo, Maria Vincenza Carriero, Michele Minopoli   +10 more
doaj   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Evolutionary dynamics of tumor progression with random fitness values

, 2010
Most human tumors result from the accumulation of multiple genetic and epigenetic alterations in a single cell. Mutations that confer a fitness advantage to the cell are known as driver mutations and are causally related to tumorigenesis. Other mutations,
Becskei, Beerenwinkel, Beisel, Bodmer, Coldman, Cowperthwaite, Durrett, Durrett, Elowitz, Feinerman, Frank, Franziska Michor, Gillespie, Gillespie, Goldie, Goldie, Haeno, Imhof, Iwasa, Iwasa, Jasmine Foo, John Mayberry, Kaern, Kassen, Kevin Leder, Knudson, Komarova, Maclean, Maley, Maley, Michor, Michor, Michor, Nowak, Nowell, Orr, Rick Durrett, Rokyta, Rozen, Sanjuán, Schweinsberg, Shah, Weissman, Wodarz   +43 more
core   +1 more source

Comparison of 10-year overall survival between patients with G1 and G2 grade Ta bladder tumors [PDF]

, 2018
To compare long-term overall survival (OS) in patients with G1 and G2 grade Ta bladder cancer after transurethral resection of bladder tumors (TURBTs).
Balan, Daniel, Borda, Angela, Busetto, Gian Maria, Chibelean, Calin Bogdan, Cioffi, Antonio, De Berardinis, Ettore, Del Giudice, Francesco, Ferro, Matteo, Lucarelli, Giuseppe, Martha, Orsolya, Matei, Victor Deliu, Porav-Hodade, Daniel, Pytel, Akos, Sin, Anca, Tataru, Sabin, Vartolomei, Mihai Dorin, Voidezan, Septimiu   +16 more
core   +2 more sources

OverAKT3: tumor progression and chemoresistance [PDF]

Cell Cycle, 2015
Akt3 is one of 3 closely related serine/threonine-protein kinases in the Akt family (Akt1, Akt2, and Akt3). Akt is among the most hyperactivated oncogenes in human cancer, regulating key cellular functions such as growth, proliferation, migration, invasion, angiogenesis, metabolism, and survival.1,2 Studies evaluating the effect of Akt isoform gene ...
Ping, Ji, Kristen M, Turner, Wei, Zhang
openaire   +2 more sources