Results 261 to 270 of about 633,270 (301)
Some of the next articles are maybe not open access.
Annual Review of Genetics, 1990
INTRODUCTION . . . , ... ,", .. ", .... ,',', .... ", ..... , ...... " .... ,', .... ,' .. """, ... "" ....... '" 616 SOMATIC CELL HYBRID STUDIES . . . . . . . ... . . .. . . . . . . . . . . , 616 Specific Chromos,?me are Asso iated with Control of Tumorlgemc ExpressIOn . . . .
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INTRODUCTION . . . , ... ,", .. ", .... ,',', .... ", ..... , ...... " .... ,', .... ,' .. """, ... "" ....... '" 616 SOMATIC CELL HYBRID STUDIES . . . . . . . ... . . .. . . . . . . . . . . , 616 Specific Chromos,?me are Asso iated with Control of Tumorlgemc ExpressIOn . . . .
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2003
Recent advances in genetics, molecular biology, and molecular pharmacology have resulted in the development of molecularly targeted therapies. Targeting specific molecular pathways essential for the survival of cancer cells would personalize treatment with the potential to improve outcome and minimize toxicities.
Jack A, Roth, Susan F, Grammer
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Recent advances in genetics, molecular biology, and molecular pharmacology have resulted in the development of molecularly targeted therapies. Targeting specific molecular pathways essential for the survival of cancer cells would personalize treatment with the potential to improve outcome and minimize toxicities.
Jack A, Roth, Susan F, Grammer
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Tumor suppressor genes in urologic tumors
Urology, 1993During the last decade remarkable progress has been made in our understanding of the malignant phenotype. There is evidence that a series of genetic changes are involved in the conversion of a normal cell to a malignant one. These changes have been directly identified with mutations in various genes usually involved in cell growth and proliferation ...
J M, Wolff, F K, Habib
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Genes, Chromosomes and Cancer, 1998
The FRA3B at 3p14.2 is the most common of the constitutive aphidicolin-inducible fragile sites. Using independent approaches, four groups of investigators have cloned and characterized this fragile site. The results of these studies have revealed that the FRA3B differs from other heretofore cloned rare fragile sites. First, instability as manifested by
M M, Le Beau +6 more
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The FRA3B at 3p14.2 is the most common of the constitutive aphidicolin-inducible fragile sites. Using independent approaches, four groups of investigators have cloned and characterized this fragile site. The results of these studies have revealed that the FRA3B differs from other heretofore cloned rare fragile sites. First, instability as manifested by
M M, Le Beau +6 more
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SIRT1: Tumor promoter or tumor suppressor?
Medical Hypotheses, 2006Over the past decade, an intensive research on the basic biology of aging has identified individual genes either directly or indirectly involved in regulating the aging process in various model organisms. This allows us to garner all the information available from studies of model organisms and to apply them to better understand aging and cancer in ...
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Dormant Tumor-Suppressor Pathways in Tumors
American Journal of Respiratory Cell and Molecular Biology, 1999It was initially thought that activation of a single oncogene such as Ras would result in tumorigenesis; however, this conclusion was based on studies in which immortalized cells were used as the target cells in transformation assays (1). Thus it was significant when in 1983 Newbold and Overell reported that an activated Ras gene failed to transform ...
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Head & neck, 1992
Tumor suppressor genes are negative regulators of cell growth. When their normal function is compromised, absence of their inhibitory effects can lead to unrestrained cell cycling and growth. Strong evidence now confirms that loss of proper function of these genes is a common occurrence leading to cancer.
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Tumor suppressor genes are negative regulators of cell growth. When their normal function is compromised, absence of their inhibitory effects can lead to unrestrained cell cycling and growth. Strong evidence now confirms that loss of proper function of these genes is a common occurrence leading to cancer.
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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
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Brain and other central nervous system tumor statistics, 2021
Ca-A Cancer Journal for Clinicians, 2021Kimberly D Miller +2 more
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