Results 241 to 250 of about 3,321,094 (294)
Transcription factor FOXP4 inversely governs tumor suppressor genes and contributes to thyroid cancer progression. [PDF]
HeliyonZhou T +7 more
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Impact of khat (Catha edulis) and oral contraceptive use on telomerase levels and tumor suppressor genes p53 and p21 in normal subjects and breast cancer patients. [PDF]
Sci RepAtroosh F +3 more
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Co-Occurring Alterations in Multiple Tumor Suppressor Genes Are Associated With Worse Outcomes in Patients With EGFR-Mutant Lung Cancer. [PDF]
J Thorac OncolStockhammer P +15 more
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Tumor Suppressor Genes in Ophthalmology
Survey of Ophthalmology, 1999 Tumor suppressor genes have a diversity of functions, but they have in common the property of inhibiting neoplastic transformation. When they become inactivated, a constraint is removed that allows cells to grow inappropriately. Mutations in these genes are now thought to be the initiating events in most cancers.
J.William Harbour, Harbour, J.William
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Neuron, 1991
For the past decade, cellular oncogenes have attracted the attention of biologists intent on understanding the molecular origins of cancer. As the present decade unfolds, oncogenes are yielding their place at center stage to a second group of actors, the tumor suppressor genes, which promise to teach us equally important lessons about the molecular ...
+7 more sources
For the past decade, cellular oncogenes have attracted the attention of biologists intent on understanding the molecular origins of cancer. As the present decade unfolds, oncogenes are yielding their place at center stage to a second group of actors, the tumor suppressor genes, which promise to teach us equally important lessons about the molecular ...
+7 more sources
Current Opinion in Genetics & Development, 2000
Although tumor suppressor genes continue to be discovered, the most recent advances have been made in attributing new and exciting functions to existing ones - such as the apparent role of VHL as a regulator of proteolysis. Great insights have also come from piecing genes together into pathways and networks. For instance the discovery that cyclin D1 is
Tracey L. Plank, Elizabeth Petri Henske
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Although tumor suppressor genes continue to be discovered, the most recent advances have been made in attributing new and exciting functions to existing ones - such as the apparent role of VHL as a regulator of proteolysis. Great insights have also come from piecing genes together into pathways and networks. For instance the discovery that cyclin D1 is
Tracey L. Plank, Elizabeth Petri Henske
openaire +3 more sources
Current Opinion in Genetics & Development, 1994
The mutation of tumor suppressor genes is thought to contribute to tumor growth by inactivating proteins that normally act to limit cell proliferation. Several tumor suppressor proteins have been identified in recent years, but only two of them, p53 and pRb, are understood in detail.
P W, Hinds, R A, Weinberg
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The mutation of tumor suppressor genes is thought to contribute to tumor growth by inactivating proteins that normally act to limit cell proliferation. Several tumor suppressor proteins have been identified in recent years, but only two of them, p53 and pRb, are understood in detail.
P W, Hinds, R A, Weinberg
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Oncogenes and tumor suppressor genes
Hospital Practice, 1993Cancer-associated genes generally can be divided into ‘dominant’ acting protooncogenes/oncogenes and ‘recessive’ tumor suppressor genes. Most simply defined, protooncogenes are identified by a gain of function as mutational damage occurs, whereas tumor suppressor genes contribute to cancer by a loss of function. However, the pace of science leads us to
E, Liu, B, Weissman
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