Results 211 to 220 of about 302,791 (267)

Histone deacetylases: Function in tumor development and therapeutic prospects (Review). [PDF]

Oncol Lett
Lin R, Zhang Y, Li H, Liang F.
europepmc   +1 more source

Biomarkers of Common Molecular Dysregulation in Tumor Tissue and Peritumor Mucosa in Head and Neck SCC: Insights into Field Cancerization. [PDF]

Int J Mol Sci
Dimitrov L, Stancheva GS, Kyurkchiyan SG, Mitkova M, Stancheva I, Valcheva S, Komitova K, Skelina S, Rangachev J, Popov TM.   +9 more
europepmc   +1 more source

The protein kinase DYRK1B is a p53 target gene and functions as a negative feedback regulator of the transcription factor RFX7. [PDF]

Cell Death Dis
Wilms G, Schwandt K, Düsterhöft S, Helmich P, Wozniak J, Kraft F, Kallabis S, Meissner F, Becker W.   +8 more
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Exon inclusion signatures enable accurate estimation of splicing factor activity. [PDF]

Nat Commun
Anglada-Girotto M, Segura-Morales C, Moakley DF, Zhang C, Miravet-Verde S, Califano A, Serrano L.   +6 more
europepmc   +1 more source

Research progress in the role and mechanism of GALNT3 in human diseases (Review). [PDF]

Biomed Rep
Su L, Lin Y, Hu X, Liu Z.
europepmc   +1 more source

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Tumor suppressor C-RASSF proteins

Cellular and Molecular Life Sciences, 2018
Human genome has ten genes that are collectedly called Ras association domain family (RASSF). RASSF is composed of two subclasses, C-RASSF and N-RASSF. Both N-RASSF and C-RASSF encode Ras association domain-containing proteins and are frequently suppressed by DNA hypermethylation in human cancers. However, C-RASSF and N-RASSF are quite different. Six C-
Hiroaki Iwasa, Shakhawoat Hossain, Yutaka Hata   +2 more
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Cell Adhesion Proteins As Tumor Suppressors

The Journal of Urology, 2002
We summarize recent progress on the role of cell adhesion molecules in biology and discuss the potential application of cell adhesion molecules for managing urological cancer.We comprehensively reviewed the literature from 1982 to 2001, including peer reviewed publications and recent abstracts from national meetings, relevant to cell adhesion molecules
Takatsugu, Okegawa, Yingming, Li, Rey-Chen, Pong, Jer-Tsong, Hsieh   +3 more
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The Petinoblastoma Tumor Suppressor Protein

1994
Publisher Summary The studies of retinoblastoma (RB) have been driven by three hypotheses: (1) RB is the suppressor of retinoblastoma and possibly the other types of cancer, (2) RB inhibits proliferation by preventing the transcription of genes critical for cell cycle progression, and (3) the inhibitory function of RB can be neutralized by ...
J Y, Wang, E S, Knudsen, P J, Welch
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The retinoblastoma tumor suppressor protein

Current Opinion in Genetics & Development, 1995
Loss of the retinoblastoma protein, pRb, appears to have a role in several human tumor types. Mice lacking pRb have been produced as models of human disease, but have a different spectrum of affected tissues. Recent work shows that the tumorigenic effects of pRb may be revealed only after additional genetic alterations, such as loss of p53. New targets/
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