Results 241 to 250 of about 755,200 (268)

Targeting Tumors

Cancer remains a global health challenge, with conventional treatments often limited by toxicity and specificity. Chimeric Antigen Receptor (CAR) T cell therapy has revolutionized cancer treatment by modifying T cells to target tumor antigens, showing significant success in hematological malignancies like acute lymphoblastic leukemia and diffuse large ...
Safiya Mehraj, Shazia Ali
openaire   +1 more source

Targeting Immunotherapy to the Tumor Microenvironment

Journal of Cellular Biochemistry, 2017
ABSTRACTTargeting drugs to the tumor microenvironment has long been appreciated as a means of increasing local concentrations and decreasing systemic toxicities. How drug targeting might apply to immune‐based therapies is less clear. In this review, we explain the immunology of cancer, with a focus on the principles of in situ vaccination.
Michael Dougan, Stephanie K. Dougan
openaire   +2 more sources

Targeting the microenvironment in solid tumors

Cancer Treatment Reviews, 2018
Tumorigenesis is a complex and dynamic process involving different cellular and non-cellular elements composed of tumor microenvironment (TME). The interaction of TME with cancer cells is responsible for tumor development, progression and drug resistance.
C. Belli, D. Trapani, G. Viale, P. D'Amico, B. Achutti Duso, P. Della Vigna, F. Orsi, G. Curigliano   +7 more
openaire   +4 more sources

Multivalent peptidomimetics for tumor targeting

2009
Introduction Multivalency is a common phenomenon in nature to increase affinity and specifity of receptor-ligand interactions, especially on the cell surface. Chemists have tried to make use of multivalent interactions in different context and have synthesized a lot of scaffolds for the assembly of multivalent receptor ligands [1]. We designed suitable
Nadine, Pannier, Valerie, Humblet, Preeti, Misra, John V, Frangioni, Wolfgang, Maison   +4 more
openaire   +2 more sources

Targeting Tregs in Tumors

Journal of Interferon & Cytokine Research, 2022
openaire   +2 more sources

Targeting a tumor microbiota

Nature Immunology, 2023
openaire   +2 more sources

Tumor‐Associated Immune‐Cell‐Mediated Tumor‐Targeting Mechanism with NIR‐II Fluorescence Imaging

Advanced Materials, 2022
Homan Kang, Shinya Yokomizo, Hyejin Chang   +2 more
exaly  

Simultaneous targeting of TGF-β/PD-L1 synergizes with radiotherapy by reprogramming the tumor microenvironment to overcome immune evasion

Cancer Cell, 2021
Yan Lan, Mahmoud Moustafa, Maximilian Knoll   +2 more
exaly  

Tumor Targeting

2021
Eva Y. Pan, Aubrey Johnson, Jennifer Zhao   +2 more
openaire   +1 more source

Current understanding of passive and active targeting nanomedicines to enhance tumor accumulation

Coordination Chemistry Reviews, 2023
Zhoujiang Chen, Ranjith Kumar Kankala
exaly