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Nanomedicines Targeting the Tumor Microenvironment
The Cancer Journal, 2015We review recent progress in cancer nanomedicine to overcome the delivery barriers in tumor microenvironment, including the understanding in the nanomedicine delivery process, stimulus-responsive delivery, and several new strategies to normalize tumor microenvironment. The application of nanomedicine in cancer immunotherapy, a renewed cancer therapy by
Rong, Tong, Robert, Langer
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Advances in Tumor Targeted Liposomes
Current Molecular Medicine, 2018Cancer remains a deadly disease for effective treatment. Although anomalous tumor microenvironment is now widely exploited for targeted chemotherapy, safe and efficacious drug delivery to tumor cells is not still warranted. Liposomes are promising biodegradable and biocompatible nanocarriers having potential amenability for surface and internal ...
A, Jain, , Jain
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Targeting Immunotherapy to the Tumor Microenvironment
Journal of Cellular Biochemistry, 2017ABSTRACTTargeting drugs to the tumor microenvironment has long been appreciated as a means of increasing local concentrations and decreasing systemic toxicities. How drug targeting might apply to immune‐based therapies is less clear. In this review, we explain the immunology of cancer, with a focus on the principles of in situ vaccination.
Michael Dougan, Stephanie K. Dougan
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Multivalent peptidomimetics for tumor targeting
2009Introduction Multivalency is a common phenomenon in nature to increase affinity and specifity of receptor-ligand interactions, especially on the cell surface. Chemists have tried to make use of multivalent interactions in different context and have synthesized a lot of scaffolds for the assembly of multivalent receptor ligands [1]. We designed suitable
Nadine, Pannier +4 more
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Tumor‐Associated Immune‐Cell‐Mediated Tumor‐Targeting Mechanism with NIR‐II Fluorescence Imaging
Advanced Materials, 2022Homan Kang +2 more
exaly
Current understanding of passive and active targeting nanomedicines to enhance tumor accumulation
Coordination Chemistry Reviews, 2023Zhoujiang Chen +2 more
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