Results 251 to 260 of about 1,151,684 (305)

Hairpin DNA-Based Nanomaterials for Tumor Targeting and Synergistic Therapy. [PDF]

open access: yesInt J Nanomedicine
Shan L   +9 more
europepmc   +1 more source

An oncolytic HAdV-5 with reduced surface charge combines diminished toxicity and improved tumor targeting. [PDF]

open access: yesMol Ther Oncol
Wienen F   +6 more
europepmc   +1 more source

Tumor vasculature-targeting nanomedicines

Acta Biomaterialia, 2021
Uncontrolled tumor growth and subsequent distant metastasis are highly dependent on an adequate nutrient supply from tumor blood vessels, which have relatively different pathophysiological characteristics from those of normal vasculature. Obviously, strategies targeting tumor vasculature, such as anti-angiogenic drugs and vascular disrupting agents ...
Ying, Zhang, Jingni, He
openaire   +2 more sources

Targeting the Tumor-Tumor Microenvironment Crosstalk

Expert Opinion on Therapeutic Targets, 2023
Cancer development and progression is a complex process influenced by co-evolution of the cancer cells and their microenvironment. However, traditional anti-cancer therapy is mostly targeted toward cancer cells. To improve the efficacy of cancer drugs, the complex interactions between the tumor (T) and the tumor microenvironment (TME) should be ...
Sunil S. Badve, Yesim Gökmen-Polar
openaire   +2 more sources

Targeting tumor cells

Current Opinion in Cell Biology, 2003
Several recent scientific and technical developments have made it possible to postulate the use of the 'magic bullet' concept; that is, the identification of specific antigens present on tumor cells that can be targeted either by therapeutic antibodies or by small molecules.
Pantea, Houshmand, Albert, Zlotnik
openaire   +2 more sources

Targeting Tumor Angiogenesis

Seminars in Oncology, 2009
Our understanding of the process of tumor angiogenesis has changed significantly since the late 1970s, when vascular endothelial growth factor (VEGF) was first identified as vascular permeability factor and later found to be the major mediator of physiologic and pathologic angiogenesis.
Puja, Gaur   +3 more
openaire   +2 more sources

Targeting Tumor Angiogenesis

2013
Four decades after the seminal work of Judah Folkman, in 1971, cancer therapies based on the suppression of neo-angiogenesis (Folkman, N Engl J Med 285:1182–1186, 1971) are becoming a reality (Verheul et al., Clin Cancer Res 14(11):3589–3597, 2008).
STAIBANO, STEFANIA   +1 more
openaire   +2 more sources

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