Results 91 to 100 of about 90,141 (272)

Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development

PROTEOMICS, EarlyView.
ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia, Mélina Blanco, Meritxell Jodar, Olivier Feudjio, Marjorie Leduc, Judit Castillo, Julie Cocquet, Rafael Oliva   +7 more
wiley   +1 more source

Testicular capillary hemangioma - A case report of a rare tumor

Indian Journal of Pathology and Microbiology, 2012
Testicular hemangioma is a very rare benign vascular neoplasm, mostly occurring in children and young adults. We present a case of capillary hemangioma of the testis in a twenty three years old male who presented with painless mass in the right scrotum ...
Shaesta N Zaidi, Amany A Fathaddin
doaj   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source

Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases [PDF]

, 2017
BACKGROUND: Cytotoxic therapy for relapsed and refractory germ cell tumors or metastatic sex cord stromal tumors is rarely effective and is often accompanied by high adverse event rates.
Albany, Costantine, Boyd, Thomas, Einhorn, Lawrence, Feldman, Darren R., Garbo, Lawrence, Josephson, Neil   +5 more
core   +1 more source

Diagnostic and therapeutic approaches of para‐testicular SCRMS in an adolescent patient: A case report

UroPrecision, EarlyView.
Abstract Background Para‐testicular rhabdomyosarcoma (RMS) is a rare and aggressive malignancy primarily affecting children and adolescents, with peak incidence between ages 2 and 5 years. Of the histological variants of RMS, the spindle cell type of RMS is particularly uncommon, accounting for approximately 5% of cases.
Kholoud Alabassi, Yaser M. Ata, Khaled Murshed, Ibrahim A. Khalil, Noheir M. Taha, Khalid Al Rumaihi   +5 more
wiley   +1 more source

Androgen receptor polymorphisms and testicular cancer risk [PDF]

, 2015
Testicular cancer (TC) is currently the most common malignant solid tumour in Caucasian males aged 15-39 years. Epidemiological evidence suggests that its onset may be due to an imbalance in the action of steroidal sex hormones and their receptors.
CARLINI, TANIA, F. Rizzo, GANDINI, Loredana, GIANNANDREA, FABRIZIO, GRASSETTI, Daniele, LENZI, Andrea, LOMBARDO, Francesco, MASCIANDARO, PAOLA, PAOLI, Donatella, V. Figura   +9 more
core   +1 more source

Comparing isoflurane and desflurane: A prospective randomised blinded clinical trial in horses undergoing elective surgery

Veterinary Record, EarlyView.
Abstract Background The recovery period is associated with the greatest risk of injury for horses undergoing anaesthesia. Recovery quality and duration can be influenced by the volatile agent. Methods This prospective, randomised blinded clinical investigation recruited 101 healthy client‐owned horses undergoing elective surgery at one UK equine ...
Kate White, John Hird, Polly Taylor
wiley   +1 more source

Disorders of sex development (DSD): an overview of recent scientific advances [PDF]

, 2014
Developments in biotechnology have radically altered clinical and research themes in the small field of disorders of sex development, as in other rare medical conditions. In the age of genetics, an increasing number of DSDs have been identified. Aided by
Conway, GS
core  

Loss of Pten causes tumor initiation following differentiation of murine pluripotent stem cells due to failed repression of Nanog. [PDF]

, 2011
Pluripotent stem cells (PSCs) hold significant promise in regenerative medicine due to their unlimited capacity for self-renewal and potential to differentiate into every cell type in the body. One major barrier to the use of PSCs is their potential risk
Banerjee, Utpal, Clark, Amander T, Jiao, Jing, Li, Xinmin, Lindgren, Anne G, Natsuhara, Kyle, Tian, E, Vincent, John J, Wu, Hong   +8 more
core   +3 more sources

Extracranial, Extragonadal Germ Cell Tumors: A Multicenter Australian Case Series

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Extragonadal germ cell tumors (EGCTs) are rare, with limited prospective data to guide treatment or inform prognosis. Incidence and treatment patterns of EGCT in Australia reflect international data and practices. Compared to testicular primaries, the prognosis of EGCT is poor, especially for primary mediastinal non‐seminoma.
Kar Ven Cavan Chow, Ciara Conduit, Sophie O'Haire, Anna Kuchel, Shirley Wong, Peter Grimison, Andrew Weickhardt, Ganes Pranavan, James Lynam, Patricia Bastick, Jeffrey Goh, Shomik Sengupta, Annabel Smith, Elizabeth Liow, David Campbell, Ming Wong, Kristina Zlatic, Peter Gibbs, Ben Tran, Chun Loo Gan   +19 more
wiley   +1 more source