Results 251 to 260 of about 368,028 (305)

Spatiotemporal dynamics of tumor-associated neutrophils: bridging the gap between cancer progression and immunotherapy. [PDF]

Mol Cancer
Chu X, Ma J, Li S, Wang M, Tian Y, Lv C.
europepmc   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Dual Targeting of HIF-1α and DLL4 by Isoxanthohumol Potentiates Immune Checkpoint Blockade. [PDF]

Int J Mol Sci
Kim D, You J, Bae SH, Jeong JH, Jung JH, Kim JA, Lee YM.   +6 more
europepmc   +1 more source

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

Advanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider, Alexander Fuchs, Michael Fichter, Vanessa Bolduan, Jenny Schunke, Özlem Akilli, Nádia C. Correia, Yannick Ehlers, Christian Czysch, Pia Winterwerber, Eliana Stanganello, Barbara Schrörs, Mustafa Diken, Christoph Eckert, Shusruto Rishik, Andreas Keller, Jörn M. Schattenberg, Stephan Grabbe, Matthias Bros, Lutz Nuhn, Leonard Kaps   +20 more
wiley   +1 more source

Liposomal nanoparticles as a drug delivery system for improved treatment of multiple myeloma. [PDF]

RSC Adv
Hanafy NAN, Kolemen S.
europepmc   +1 more source

Mechanisms and intervention strategies of microenvironment-mediated drug resistance in multiple myeloma. [PDF]

Cancer Cell Int
Xiaoling Z, Qi C, Tingting Y, Di H, Meijia Y.   +4 more
europepmc   +1 more source

Emerging roles of haemostatic proteins as markers of disease progression and prognosis in breast cancer. [PDF]

Explor Target Antitumor Ther
Izuegbuna OO.
europepmc   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment. [PDF]

Adv Sci (Weinh)
Wang W, Mu S, Zhang J, Shan G, Li X, Wang R, Guo T, He X.   +7 more
europepmc   +1 more source

Anti-angiogenic therapies in cancer: from endogenous inhibitors to bispecific VEGF x PD-(L)1 antibodies. [PDF]

Front Immunol
Álvarez-Vallina L, Sanz L.
europepmc   +1 more source