Results 1 to 10 of about 1,860,910 (290)
Enhancement of doxorubicin anti-cancer activity by vascular targeting using IsoDGR/cytokine-coated nanogold [PDF]
Journal of Nanobiotechnology, 2021 Background Gold nanospheres tagged with peptides containing isoDGR (isoAsp-Gly-Arg), an αvβ3 integrin binding motif, represent efficient carriers for delivering pro-inflammatory cytokines to the tumor vasculature.
Angelo Corti +8 more
doaj +2 more sources
Vascular Endothelial Cells: Heterogeneity and Targeting Approaches
Cells, 2021 Forming the inner layer of the vascular system, endothelial cells (ECs) facilitate a multitude of crucial physiological processes throughout the body. Vascular ECs enable the vessel wall passage of nutrients and diffusion of oxygen from the blood into ...
Jan K. Hennigs +3 more
doaj +3 more sources
Combination of vascular surgery with novel vascular targeting agents as cancer therapeutics [PDF]
Frontiers in OncologyLocally advanced solid tumors, characterized by complex involvement or encasement of major vascular structures, present a significant challenge in curative oncology. Achieving microscopically negative margins often mandates extensive surgical procedures,
Jianxin Dong +3 more
doaj +2 more sources
The Evolution of Safe and Effective Coaguligands for Vascular Targeting and Precision Thrombosis of Solid Tumors and Vascular Malformations [PDF]
Biomedicines, 2021 L S McRobb +2 more
exaly +2 more sources
Vascular targeting of nanoparticles for molecular imaging of diseased endothelium [PDF]
Advanced Drug Delivery Reviews, 2017 Efstathios Karathanasis +2 more
exaly +2 more sources
Vascular Targeting of a Gold Nanoparticle to Breast Cancer Metastasis [PDF]
Journal of Pharmaceutical Sciences, 2015 Efstathios Karathanasis +2 more
exaly +2 more sources
Frontiers in Chemistry, 2021 Gold nanoparticles functionalized with isoDGR, a tripeptide motif that recognizes αvβ3 integrin overexpressed in tumor vessels, have been used as nano-vectors for the delivery of cytokines to tumors.
Angelina Sacchi +8 more
doaj +1 more source
Neuropilin-1 and Integrins as Receptors for Chromogranin A-Derived Peptides
Pharmaceutics, 2022 Human chromogranin A (CgA), a 439 residue-long member of the “granin” secretory protein family, is the precursor of several peptides and polypeptides involved in the regulation of the innate immunity, cardiovascular system, metabolism, angiogenesis ...
Angelo Corti +2 more
doaj +1 more source
Journal of Nanobiotechnology, 2023 Background Early detection and removal of bladder cancer in patients is crucial to prevent tumor recurrence and progression. Because current imaging techniques may fail to detect small lesions of in situ carcinomas, patients with bladder cancer often ...
Massimo Alfano +17 more
doaj +1 more source
Liposomal Drug Delivery Systems for Cancer Therapy: The Rotterdam Experience
Pharmaceutics, 2022 At the Nanomedicine Innovation Center (NICE) at the Erasmus MC in Rotterdam, we have approached the treatment of cancer by starting with a vision of first establishing a platform that enables us to overcome the low levels of drugs delivered to tumors and
Mohamadreza Amin +4 more
doaj +1 more source