Results 101 to 110 of about 269,778 (316)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes [PDF]

, 2012
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs.
Lorin, V, Tangy, Frédéric, Vabret, Astrid, Vidalain, Pierre-Olivier, Tangy, F, Escriou, Nicolas, Millet, J, Escriou, N, Law, H, Albert, ML, Millet, Jean, K., Nal, B, Law, Helen, Albert, Matthew L, Vabret, A, Nal, Béatrice, Lorin, Valérie, Vidalain, PO, Mesel-Lemoine, Mariana   +18 more
core   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Arming vaccinia virus for pancreatic cancer oncolytic virotherapy

, 2011
PhDVaccinia virus is a 250-300nm enveloped DNA virus from the poxvirus family and is used as a vector for oncolytic viral gene therapy. No unique cell surface receptor has been identified for Vaccinia virus and the reasons for its tropism for cancer ...
Hiley, Crispin
core  

Influence of IL-10RA and IL-22 polymorphisms on outcome of hepatitis C virus infection.

, 2007
BACKGROUND: Two receptor chains, IL-10RA and IL-10RB, are known to mediate the functions of interleukin-10 (IL-10), which has been shown to be involved in the progression of persistent hepatitis C virus (HCV) infection. Little information is available on
Thursz, Mark, Hill, Adrian V, Hill, Adrian, Knapp, S, Zhang, Lyna, Thomas, Howard C, Yee, LJ, Thomas, HC, Hennig, Branwen J, Wright, Mark, Yee, Leland J, Hennig, BJ, Frodsham, Angela J, Frodsham, AJ, Zhang, L, Wright, M, Hellier, Simon, Thursz, M, Knapp, Susanne, Hellier, S, Hill, AV   +20 more
core   +1 more source

Modulation of antigen-specific T-cells as immune therapy for chronic infectious diseases and cancer [PDF]

, 2014
Copyright: © 2014 Li, Symonds, Miao, Sanderson and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Miao, T, Ping eWang, Suling Li, Tizong Miao, Sanderson, I, Tizong eMiao, Ian eSanderson, Alistair L. J. Symonds, Ping Wang, Suling eLi, Ian Sanderson, Wang, P, Li, S, Symonds, ALJ   +13 more
core   +1 more source

Immunotherapy for virus-related hepatocellular carcinoma: recent progress and future directions

Annals of Medicine
Background Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, with hepatitis B virus (HBV) and hepatitis C virus (HCV) infections remaining the predominant etiological factors. Chronic viral infection not only drives
Ruijuan Song, Mingyuan Li, Shengqiang Tang, Guoliang Zhang   +3 more
doaj   +1 more source

Fanconi Anemia Patients Are More Susceptible to Infection with Tumor Virus SV40

PLoS ONE, 2013
Fanconi anemia (FA) is a recessive DNA repair disease characterized by a high predisposition to developing neoplasms. DNA tumor polyomavirus simian virus 40 (SV40) transforms FA fibroblasts at high efficiency suggesting that FA patients could be highly susceptible to SV40 infection.
Manola Comar, Manola Comar, Daniela De Rocco, Enrico Cappelli, Nunzia Zanotta, Roberta Bottega, Johanna Svahn, Piero Farruggia, Aldo Misuraca, Fabio Corsolini, Carlo Dufour, Anna Savoia   +11 more
openaire   +5 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Factors associated with testing for hepatitis C in an internet-recruited sample of men who have sex with men.

, 2001
BACKGROUND: Nearly 4 million individuals in the United States (1.8%) have been infected with hepatitis C virus, yet few are aware of their infection. GOAL: To identify correlates associated with hepatitis C virus testing among a sample of men who have ...
Diclemente, RJ, Hergenrather, KC, Rhodes, SD, Yee, LJ   +3 more
core   +1 more source