Results 211 to 220 of about 1,122,815 (355)

Cutaneous-Tropism Viruses: Unraveling Pathogenetic Mechanisms and Immunoprophylactic Strategies. [PDF]

Life (Basel)
Lupoae M, Elisei AM, Iacob A, Lupoae A, Tatu AL, Niculeț E, Căuș MN, Batîr D, Nechita A, Matei MN, Ștefan CS, Lisă EL, Irinel L, Tutunaru D.   +13 more
europepmc   +1 more source

Relation of Burkitt's tumor-associated herpes-ytpe virus to infectious mononucleosis.

Proceedings of the National Academy of Sciences of the United States of America, 1968
G. Henle, W. Henle, V. Diehl
semanticscholar   +1 more source

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

HPV, EBV, CMV, and HSV in Head and Neck Cancer: Molecular Detection, Seroprevalence, and Clinical Correlations. [PDF]

Biology (Basel)
Onel M, Kirkoyun Uysal H, Ulusan M, Ayeser U, Sarsar K, Ucar YA, Yoldas O, Hulikyan A, Kiraz FG, Uysal AM, Celik M, Demirci M, Agacfidan A.   +12 more
europepmc   +1 more source

Mining the virome for insights into type 1 diabetes [PDF]

, 2018
Park, Arnold, Zhao, Guoyan
core   +2 more sources

Cell and molecular biology of simian virus 40: implications for human infections and disease.

Journal of the National Cancer Institute, 1999
J. Butel, J. Lednicky
semanticscholar   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

COVID-19 infection and cancer regression: a review of current evidence, potential mechanisms, and clinical perspectives on a Paradoxical phenomenon. [PDF]

Infect Agent Cancer
Ogieuhi IJ, Ajekiigbe VO, Agbo CE, Anthony CS, Christopher AA, Onyehalu JC, Agu MC, Mbaji SM, Akingbola A, Ahmed B, Ogieuhi O, Akinmeji O.   +11 more
europepmc   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

Advanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang, Shiyu Liu, Yixiao Zhu, Meleana M. Hinchman, Nan Qiao, Xuejun Li, Weiqian Dai, Yingying Tong, Man Xing, Jiling Ren, John S. L. Parker, Yingying Guo, Dongming Zhou   +12 more
wiley   +1 more source

Context-Specific Diversity of Antimicrobial Functions of Interferon-Stimulated Genes. [PDF]

Viruses
Harioudh MK, Sarkar SN.
europepmc   +1 more source