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An AOP-Based Integrated In Vitro and In Vivo Assessment of the Non-Genotoxic Carcinogenic Potential of Multi-Walled Carbon Nanotubes [PDF]
NanomaterialsMulti-walled carbon nanotubes (MWCNTs) are increasingly incorporated into industrial and consumer products, raising concerns about potential carcinogenicity because their physicochemical properties vary widely among materials.
Minju Kim +5 more
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Ectoine Globally Hypomethylates DNA in Skin Cells and Suppresses Cancer Proliferation
Marine Drugs, 2023 Epigenetic modifications, mainly aberrant DNA methylation, have been shown to silence the expression of genes involved in epigenetic diseases, including cancer suppression genes.
Majjid A. Qaria +7 more
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YTHDF1 Aggravates the Progression of Cervical Cancer Through m6A-Mediated Up-Regulation of RANBP2
Frontiers in Oncology, 2021 N6-methyladenosine (m6A) is the most common post-transcriptional modification of RNA in eukaryotes, which has been demonstrated to play important roles in various cancers. YTHDF1 acts as a crucial m6A “reader” and regulates the fate of m6A modified mRNA.
Haocheng Wang +8 more
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Frontiers in Oncology, 2022 Colorectal cancer (CRC), one of the cancers with highest mortality, involves complicated molecular mechanisms leading to the onset of malignant phenotypes.
Binle Tian +5 more
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Veterinary Research, 2022 Avian leukosis virus subgroup J (ALV-J) can cause neoplastic diseases in poultry and is still widely prevalent in China. Chicken telomerase reverse transcriptase (chTERT) is the core component of telomerase, which is closely related to the occurrence and
Yong Xiang +4 more
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Open Medicine, 2023 Circular RNAs have been reported to be widely involved in cancer cell tumorigenesis and drug resistance; here, the aim of this study was to investigate whether circRNA Integrin Subunit Alpha 7 (ITGA7) (circ_ITGA7) was associated with the tumor growth and
Li Wei +4 more
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Frontiers in Genetics, 2021 ObjectiveThis study aimed to investigate the role and potential regulatory mechanism of citron kinase (CIT) in esophageal squamous cell carcinoma (ESCC).MethodsCitron kinase (CIT) expression in ESCC tissues was analyzed based on the microarray dataset ...
Wenfeng Lu +6 more
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Frontiers in Cell and Developmental Biology, 2023 Characterization of cancer cells and neural stem cells indicates that tumorigenicity and pluripotency are coupled cell properties determined by neural stemness, and tumorigenesis represents a process of progressive loss of original cell identity and gain
Ying Cao, Ying Cao, Ying Cao
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Frontiers in Cell and Developmental Biology, 2021 BackgroundFocusing on antiangiogenesis may provide promising choices for treatment of gastric cancer (GC). This study aimed to investigate the mechanistic role of BCAT1 in the pathogenesis of GC, particularly in angiogenesis.MethodsBioinformatics and ...
Xiong Shu +8 more
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Frontiers in Bioscience-Landmark, 2023 Background: The stemness characteristics of cancer cells, such as self-renewal and tumorigenicity, are considered to be responsible, in part, for tumor metastasis.
Chendan Zou +10 more
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