Results 31 to 40 of about 155,806 (387)
GPER-induced signaling is essential for the survival of breast cancer stem cells. [PDF]
, 2020 G protein-coupled estrogen receptor-1 (GPER), a member of the G protein-coupled receptor (GPCR) superfamily, mediates estrogen-induced proliferation of normal and malignant breast epithelial cells.
Chan, Yu-Tzu +12 more
core +2 more sources
Frontiers in Bioscience-Landmark, 2023 Background: The stemness characteristics of cancer cells, such as self-renewal and tumorigenicity, are considered to be responsible, in part, for tumor metastasis.
Chendan Zou +10 more
doaj +1 more source
Cell softness regulates tumorigenicity and stemness of cancer cells
EMBO Journal, 2020 Identifying and sorting highly tumorigenic and metastatic tumor cells from a heterogeneous cell population is a daunting challenge. Here, we show that microfluidic devices can be used to sort marker‐based heterogeneous cancer stem cells (CSC) into ...
Jiadi Lv +21 more
semanticscholar +1 more source
Fucosyltransferase 1 and 2 play pivotal roles in breast cancer cells. [PDF]
, 2019 FUT1 and FUT2 encode alpha 1, 2-fucosyltransferases which catalyze the addition of alpha 1, 2-linked fucose to glycans. Glycan products of FUT1 and FUT2, such as Globo H and Lewis Y, are highly expressed on malignant tissues, including breast cancer ...
Chang, Nai-Chuan +9 more
core +2 more sources
Frontiers in Oncology, 2021 ObjectiveTo investigate the effects of NK4 gene on the properties and tumorigenicity in laryngeal squamous cell carcinoma cell.MethodsHere, we used the attenuated Salmonella carrying the NK4 gene to transfect the AMC-HN-8 cells and detected the ...
Shoukai Zhang +6 more
doaj +1 more source
Plasticity and Tumorigenicity [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 France Licence. The research fields of developmental biology and oncology have always been tightly linked, since the times of Rudolf Virchow's cellular theory (>omnis cellula e cellula>) and embryonal rest hypothesis.
Campos-Sánchez, Elena +2 more
openaire +2 more sources
Essential gene pathways for glioblastoma stem cells: clinical implications for prevention of tumor recurrence. [PDF]
, 2011 Glioblastoma (World Health Organization/WHO grade IV) is the most common and most aggressive adult glial tumor. Patients with glioblastoma, despite being treated with gross total resection and post-operative radiation/chemotherapy, will almost always ...
Choe, Jinny +6 more
core +1 more source
Biomedicines, 2022 Cell therapy products have significant limitations, such as storage instability, difficulties with transportation, and toxicity issues such as tumorigenicity and immunogenicity.
Min Heui Yoo, A-Ram Lee, Kyoung-Sik Moon
doaj +1 more source
Nature Cell Biology, 2018 N6-methyladenosine (m6A) messenger RNA methylation is a gene regulatory mechanism affecting cell differentiation and proliferation in development and cancer.
J. Liu +19 more
semanticscholar +1 more source
Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication. [PDF]
, 2016 The transcription factor Yin Yang 1 (YY1) is frequently overexpressed in cancerous tissues compared to normal tissues and has regulatory roles in cell proliferation, cell viability, epithelial-mesenchymal transition, metastasis and drug/immune resistance.
Bonavida, Benjamin +2 more
core +2 more sources