Results 171 to 180 of about 5,827 (204)

MUC1-C dependence in treatment-resistant prostate cancer uncovers a target for antibody-drug conjugate therapy. [PDF]

JCI Insight
Shigeta K, Daimon T, Hongo H, Ku SY, Ozawa H, Haratake N, Fushimi A, Nakashoji A, Bhattacharya A, Takamori S, Kono M, Rokugo M, Baba Y, Kosaka T, Oya M, Jacobi J, Long MD, Beltran H, Kufe D.   +18 more
europepmc   +1 more source

FVTF inhibits hepatocellular carcinoma stem properties via targeting DNMT1/miR-34a-5p/FoxM1 axis. [PDF]

Chin Med
Cao XC, Peng J, Qiu YB, Zhu W, Cao JG, Zou H, Yu ZZ, Wu D, Lu SS, Huang W, Yi H, Xiao ZQ.   +11 more
europepmc   +1 more source

Potential use of glioblastoma tumorsphere: clinical credentialing

Archives of Pharmacal Research, 2015
A decade ago, cancer stem cells (CSCs) were introduced as target cells for an innovative cancer treatment. Particularly, there have been a lot of biological researches on glioblastoma (GBM) CSCs. However, as there is a comprehensive change in the concept of CSCs, it is required to review how the different CSCs for patients can be clinically used, or ...
Seok-Gu Kang, Jae-Ho Cheong, Sun Ho Kim
exaly   +4 more sources

Some of the next articles are maybe not open access.

Related searches:

Establishing Primary Human Glioblastoma Tumorsphere Cultures from Operative Specimens

Methods in Molecular Biology, 2018
In vitro propagation of patient-derived glioblastoma (GBM) cells can be achieved either by adherent monolayer culture, already described in Chapter 3 , or by tumorsphere culture in suspension. Here, we provide a detailed protocol for establishing patient-derived tumorsphere cultures.
Joshua David Frenster, Dimitris G Placantonakis   +1 more
exaly   +3 more sources

Quantification of tumorsphere migration with a physics‐based machine learning method

Cytometry Part A: the Journal of the International Society for Analytical Cytology, 2023
AbstractCurrent analysis techniques available for migration assays only provide quantitative measurements for overall migration. However, the potential of regional migration analyses can open further insight into migration patterns and more avenues of experimentation with the same assays.
Thomas I-H Park, Vickie Bo Kyung Shim
exaly   +3 more sources

Profiling of Aldehyde Dehydrogenase Isoforms inIn VitroFormed Tumorspheres

Anticancer Research, 2021
Aldehyde dehydrogenases (ALDHs) are considered as markers for normal and cancer stem cells (CSC) and are involved in cell metabolism, proliferation, differentiation, stemness, and retinoic acid (RA) biosynthesis. The aim of the present study was to identify the ALDH isoforms that are associated with the CSC phenotype in non-small cell lung and ...
Ilias, Tsochantaridis, Georgia-Persephoni, Voulgaridou, Alexandra, Giatromanolaki, Michael I, Koukourakis, Mihalis I, Panayiotidis, Aglaia, Pappa   +5 more
openaire   +2 more sources

Enrichment of Cancer Stem Cells in a Tumorsphere Assay

2022
Cancer stem cells (CSCs) are a small subpopulation of self-renewing cancer cells that are present within tumors. CSCs possess tumor initiation potential as well as the ability to resist toxic compounds and chemotherapeutic agents through the upregulation of drug efflux transporters, DNA repair pathways, and survival cascades.
Abhijeet P, Deshmukh, Petra, den Hollander, Nick A, Kuburich, Suhas, Vasaikar, Robiya, Joseph, Sendurai A, Mani   +5 more
openaire   +2 more sources

P10.07.B Differential YAP activity in human glioblastoma tumorspheres

Neuro-Oncology, 2022
Abstract Background Although glioblastoma (GBM) is the most common primary brain tumor, the best available treatment options are still associated with poor prognosis. Recently, the Hippo/YAP signaling pathway has been emerged as an important driver of GBM.
E Kim, Y Oh, S Kang
openaire   +1 more source

Translational impact of patient-derived glioblastoma tumorspheres.

Journal of Clinical Oncology, 2016
2025Background: Advances from glioma stem-like cell research, though increasing our knowledge on glioblastoma biology, do not influence clinical decisions yet.
Maurizio Martini, Quintino Giorgio D'Alessandris, Mauro Biffoni, Mariachiara Bucciarelli, Tonia Cenci, Ruggero De Maria, Luigi Maria Larocca, Lucia Ricci Vitiani, Roberto Pallini   +8 more
openaire   +1 more source

Growth of tumorspheres from peripherally circulating tumor cells.

Journal of Clinical Oncology, 2012
2 Background: Even after the complete resection of a malignant tumor the menace remains, that cells that have dissociated from the tumor might resettle in distant organs and grow into life-threatening metastases. Therefore we have developed an approach (maintrac) to detect and monitor the circulating tumor suspect epithelial cells in blood.
Dorothea Zimon, Monica Pizon, Ulrich A. Pachmann, Katharina Pachmann   +3 more
openaire   +1 more source