Results 61 to 70 of about 7,601 (178)

Pax3/7 regulates neural tube closure and patterning in a non-vertebrate chordate

open access: yesFrontiers in Cell and Developmental Biology, 2022
Pax3/7 factors play numerous roles in the development of the dorsal nervous system of vertebrates. From specifying neural crest at the neural plate borders, to regulating neural tube closure and patterning of the resulting neural tube.
Kwantae Kim   +2 more
doaj   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

open access: yesAllergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz   +22 more
wiley   +1 more source

IDENTIFICATION OF SECONDARY METABOLITE COMPOUNDS IN TUNICATE (Polycarpa aurata) ASSOCIATED BACTERIA

open access: yesJurnal Kedokteran Diponegoro, 2021
Background: Marine biodiversity in the last few decades has been explored and utilized as marine natural products. The secondary metabolites produced by marine organisms are utilized by humans in various aspects of life.
Sheila Raisa   +3 more
doaj   +1 more source

Characterization of dermatan sulfate and chondroitin sulfate profiles during brain regeneration in Styela plicata

open access: yesThe FEBS Journal, EarlyView.
Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal   +5 more
wiley   +1 more source

Constituintes químicos da ascídia didemnum psammatodes (sluiter, 1895) coletada na costa cearense Chemical constituent from the ascidian didemnum psammatodes (sluiter, 1895) collecter on the shores of ceara state

open access: yesQuímica Nova, 2007
Chemical investigation of the methanolic extract of the ascidian Didemnum psammatodes has led to the identification of the nucleosides 2'-deoxyuridine (1), thymidine (2), 2'-deoxyinosine (3) and 2'-deoxyguanosine (4), the steroids cholestanol ...
Renata Takeara   +5 more
doaj   +1 more source

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

open access: yesThe FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari   +7 more
wiley   +1 more source

Molecular evolution and functional characterisation of tunicate xenobiotic receptors

open access: yes, 2015
Marine microorganisms generate a wide range of ’bioactive’ compounds that can have far-reaching effects on biological and ecological processes. Metazoans have developed specialised biochemical pathways that metabolise and eliminate potentially toxic ...
Richter, Ingrid (11703854)
core   +1 more source

The Greenland–Scotland Ridge in a Changing Ocean: Time to Act?

open access: yesMarine Ecology, EarlyView.
ABSTRACT The Greenland–Scotland Ridge is a submarine mountain that rises up to 500 m below the sea surface and extends from the east coast of Greenland to the continental shelf of Iceland and across the Faroe Islands to Scotland. The ridge not only separates deeper ocean basins on either side, that is, the North Atlantic and Arctic oceans, but also ...
Christophe Pampoulie   +2 more
wiley   +1 more source

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

Recent Advances in Pickering Emulsion Templated Phase Change Material Microcapsules: Design, Fabrication, and Multifunctional Applications

open access: yesENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 6, November 2026.
Fabrication process of phase change microcapsules using a Pickering emulsion template method and their subsequent applications. The increasing demand for efficient thermal energy storage systems has driven the development of phase change material microcapsules (PCMMs), which provide high energy‐storage density, reversible phase change, and reduced ...
Ziyan Li   +4 more
wiley   +1 more source

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