Results 91 to 100 of about 1,595,436 (304)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
A Novel Tuning Method of PD With Gravity Compensation Controller for Robot Manipulators
IEEE Access, 2020 Proportional-Derivative (PD) control is one of the most widely used controllers, especially for robot manipulators. When the robot presents gravitational terms, PD control cannot guarantee position convergence, therefore compensation is required such as ...
Adolfo Perrusquia +2 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Split-cavity tuning of a rectangular axion haloscope operating around 8.4 GHz
Frontiers in PhysicsThe axion haloscope is the currently most sensitive method to probe the vanishingly small coupling of this prominent Dark Matter candidate to photons. To scan a sizeable axion Dark Matter parameter space, the cavities that make up the haloscope need to ...
Jessica Golm +6 more
doaj +1 more source
Perspectives on Medical Education, 2013 Medical curricula, like healthcare systems and medical practice, have a strong cultural component and vary considerably between countries. Increasing mobility of medical graduates, and increasing pressure to ensure they are all fit for practice, have ...
Richard Marz +4 more
doaj +1 more source
Tuning Elliptic Filters with a 'Tuning Biquad'
, 2009 This paper presents an optimum tuning procedure for high-order low-pass (LP) elliptic filters. Since elliptic filters are often used to satisfy very tight specifications, they often need to be tuned accurately. In this paper, we describe the tuning of one biquad, the 'tuning biquad', in a cascade of biquads.
Drazen Jurisic +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
, 2018 In real-world applications, commercial off-the-shelf systems are utilized for performing automated facial analysis including face recognition, emotion recognition, and attribute prediction.
Chhabra, Saheb +3 more
core +1 more source