Results 91 to 100 of about 1,512,342 (361)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Wide tuning-range planar filters using lumped-distributed coupled resonators [PDF]
, 2005 This paper describes a discretely tunable filter topology based on lumped-distributed coupled transmission lines, particularly suitable for microelectromechanical systems switching devices.
Carey-Smith, BE +3 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The time-domain response of coupled-resonator filters with applications to tuning [PDF]
, 2004 This thesis develops a new theory of tuning filters based on the time-domain response of the filter. These methods are shown to work very well for all-pole coupledresonator filters in particular, and may be applied to automated tuning of filters ...
Dunsmore, Joel Philip
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
, 2004 In order to achieve the optimal design based on some specific criteria by applying conventional techniques, sequence of design, selected locations of PSSs are critical involved factors.
Tippayachai, Jarurote +5 more
core +1 more source
Tunable IDC Phase Shifter Based on Semiautomated Deposition of Graphene
IET Microwaves, Antennas & PropagationIn this work, a graphene‐based tunable phase shifter is proposed which deploys a semiautomated procedure for graphene deposition leading to a high‐quality graphene transfer.
Warda Saeed, Muhammad Yasir
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Electronic tuning of misaligned coils in wireless power transfer systems [PDF]
, 2014 The misalignment and displacement of inductively coupled coils in a wireless power transfer system (WPT) can degrade the power efficiency and limit the amount of power that can be transferred.
Whidborne, James F. +2 more
core +1 more source