Results 101 to 110 of about 1,595,436 (304)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Trade-Off Analysis of Drive Dynamics Considering Speed and Current Loops

Energies
Electric drive control is an important area of research due to its ubiquity. In particular, multi-phase induction machines are an important field due to their inherent robustness.
Manuel R. Arahal, Manuel G. Satué, Francisco Colodro, Juana M. Martínez-Heredia   +3 more
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Microwave Absorption Properties of Ceramics Based on BiFeO₃ Modified with Ho

Solids
Ceramic samples of Bi1−xHoxFeO3, where x = 0.00–0.50, with a modifier concentration variation step ∆x = 0.05–0.10, were prepared by a two-step solid-phase synthesis followed by sintering using conventional ceramic technology.
Pavel Astafev, Konstantin Andryushin, Aleksey Pavelko, Alexander Lerer, Yakov Reizenkind, Ekaterina Glazunova, Lidiya Shilkina, Inna Andryushina, Alexandr Nagaenko, Larisa Reznichenko   +9 more
doaj   +1 more source

Tune Field [PDF]

NIME 2021, 2021
Guadalupe Babio Fernandez, Kent Larson
openaire   +1 more source

String fine tuning

, 1992
We develop further a new geometrical model of a discretized string, proposed in [1] and establish its basic physical properties. The model can be considered as the natural extention of the usual Feynman amplitude of the random walks to random surfaces ...
Savvidy, G., Savvidy, K.
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Piloting the Appreciative Tuning Protocol: Improving Integration through a Collaborative Professional Development Model

International Journal for the Scholarship of Teaching and Learning
This qualitative, self-reflection study was conducted by three instructors who had recently participated in a workshop on Principled Innovation, a character development framework designed in their college of education.
Teresa S. Foulger, Ashleigh King, Shyla Gonzalez-Dogan   +2 more
doaj   +1 more source

Tuning Tempered Transitions

, 2010
The method of tempered transitions was proposed by Neal (1996) for tackling the difficulties arising when using Markov chain Monte Carlo to sample from multimodal distributions.
Behrens, Gundula, Friel, Nial, Hurn, Merrilee   +2 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source