Results 71 to 80 of about 2,331,313 (323)
Comments on the Hierarchy Problem in Effective Theories [PDF]
, 2014 We discuss aspects of the hierarchy problem in effective theories with light scalars and a large, physical ultraviolet (UV) cutoff. We make two main points: (1) The (naive) fine-tuning observed in an effective theory does not automatically imply that the
Kobakhidze, Archil +1 more
core +2 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Research on Parameter Design and Control Method for Current Source Inverter–Fed IM Drive Systems
Machines, 2022 In the current source inverter (CSI)-fed inductor motor (IM) drive system, DC-bus inductance and AC-filter capacitance have a direct impact on the dynamic response speed, power quality and power density.
Pengyun Song, Yanghui Liu, Chao Liu
doaj +1 more source
CoPhy: A Scalable, Portable, and Interactive Index Advisor for Large Workloads [PDF]
, 2011 Index tuning, i.e., selecting the indexes appropriate for a workload, is a crucial problem in database system tuning. In this paper, we solve index tuning for large problem instances that are common in practice, e.g., thousands of queries in the workload,
Ailamaki, Anastasia +2 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Geophysical Research Letters, 2021 During the early to mid‐Holocene vegetation expanded to cover much of the present‐day Sahara. Although driven by a well‐understood difference in the orbital configuration, general circulation models have generally failed to simulate the required rainfall
Peter O. Hopcroft +2 more
doaj +1 more source
An interferometer tracking radar system [PDF]
, 1969 Fine tuning acquisition and tracking interferometer radar system uses a first antenna array of at least three receiving antennas. Array includes a reference antenna, a coarse tuning antenna, and a fine tuning antenna aligned on a receiving axis.
Broderick, R. F.
core +1 more source
Robust Tuning Datasets for Statistical Machine Translation
, 2017 We explore the idea of automatically crafting a tuning dataset for Statistical Machine Translation (SMT) that makes the hyper-parameters of the SMT system more robust with respect to some specific deficiencies of the parameter tuning algorithms.
Nakov, Preslav, Vogel, Stephan
core +1 more source
How behavioral constraints may determine optimal sensory representations [PDF]
, 2006 The sensory-triggered activity of a neuron is typically characterized in terms of a tuning curve, which describes the neuron's average response as a function of a parameter that characterizes a physical stimulus.
Adolphs +56 more
core +5 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source