Results 51 to 60 of about 204,183 (308)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Amplitude modulated near-wall cycle in a turbulent boundary layer under an adverse pressure gradient

Archives of Mechanics, 2013
This paper presents the effect of amplitude modulation of small-scale turbulence by large-scale structures in a turbulent boundary layer subjected to an adverse pressure gradient.
A. Dróżdż, W. Elsner
doaj   +1 more source

Turbulent boundary layer equations [PDF]

Comptes Rendus. Mathématique, 2002
We study a boundary layer problem for the Navier–Stokes-alpha model obtaining a generalization of the Prandtl equations which we conjecture to represent the averaged flow in a turbulent boundary layer. We study the equations for the semi-infinite plate, both theoretically and numerically.
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

DNS Study of Effects of Suddenly-Vanishing Wall Heating in Turbulent Boundary Layer

Journal of Thermal Science and Technology, 2012
The objective of this study is to investigate a thermal field in the turbulent boundary layer by means of direct numerical simulation (DNS), in which the wall heating has suddenly vanished in the downstream region, i.e., the wall is heated by a constant ...
Hirofumi HATTORI, Syohei YAMADA, Tomoya HOURA   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Response of the Land‐Atmosphere System Over North‐Central Oklahoma During the 2017 Eclipse

Geophysical Research Letters, 2018
On 21 August 2017, a solar eclipse occurred over the continental United States resulting in a rapid reduction and subsequent increase of solar radiation over a large region of the country.
D. D. Turner, V. Wulfmeyer, A. Behrendt, T. A. Bonin, A. Choukulkar, R. K. Newsom, W. A. Brewer, D. R. Cook   +7 more
doaj   +1 more source

Boundary-layer turbulent processes and mesoscale variability represented by numerical weather prediction models during the BLLAST campaign [PDF]

Atmospheric Chemistry and Physics, 2016
This study evaluates the ability of three operational models, with resolution varying from 2.5 to 16 km, to predict the boundary-layer turbulent processes and mesoscale variability observed during the Boundary Layer Late-Afternoon and Sunset ...
F. Couvreux, E. Bazile, G. Canut, Y. Seity, M. Lothon, F. Lohou, F. Guichard, E. Nilsson   +7 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

RANS Modeling of Stably Stratified Turbulent Boundary Layer Flows in OpenFOAM®

E3S Web of Conferences, 2015
Quantifying mixing processes relating to the transport of heat, momentum, and scalar quantities of stably stratified turbulent geophysical flows remains a substantial task. In a stably stratified flow, such as the stable atmospheric boundary layer (SABL),
Wilson Jordan M., Venayagamoorthy Subhas K.   +1 more
doaj   +1 more source