Results 71 to 80 of about 34,613 (317)

Response of the Land‐Atmosphere System Over North‐Central Oklahoma During the 2017 Eclipse

Geophysical Research Letters, 2018
On 21 August 2017, a solar eclipse occurred over the continental United States resulting in a rapid reduction and subsequent increase of solar radiation over a large region of the country.
D. D. Turner, V. Wulfmeyer, A. Behrendt, T. A. Bonin, A. Choukulkar, R. K. Newsom, W. A. Brewer, D. R. Cook   +7 more
doaj   +1 more source

Boundary-layer turbulent processes and mesoscale variability represented by numerical weather prediction models during the BLLAST campaign [PDF]

Atmospheric Chemistry and Physics, 2016
This study evaluates the ability of three operational models, with resolution varying from 2.5 to 16 km, to predict the boundary-layer turbulent processes and mesoscale variability observed during the Boundary Layer Late-Afternoon and Sunset ...
F. Couvreux, E. Bazile, G. Canut, Y. Seity, M. Lothon, F. Lohou, F. Guichard, E. Nilsson   +7 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Soft turbulence in the atmospheric boundary layer

AIP Conference Proceedings, 1993
In this work we compare the spectral properties of the daily medium temperature fluctuations with the experimental results of the Chicago Group, in which the local temperature fluctuations were measured in a helium cell. The results suggest that the dynamics of the daily temperature fluctuations is determined by the oft turbulent state of the ...
Jánosi, Imre M., Vattay, Gábor
openaire   +2 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

MECHANISM OF WALL TURBULENCE IN BOUNDARY LAYER FLOW [PDF]

Modern Physics Letters B, 2009
The energy gradient method is used to analyze the turbulent generation in the transition boundary layer flow. It is found that the maximum of the energy gradient function occurs at the wall for the Blasius boundary layer flow. At this location under a sufficiently high Reynolds number, even a low level of free-stream disturbance can cause the ...
Dou, Hua-Shu, Khoo, Boo Cheong
openaire   +2 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Large-eddy simulation of low-frequency unsteadiness in a turbulent shock-induced separation bubble

, 2009
The need for better understanding of the low-frequency unsteadiness observed in shock wave/turbulent boundary layer interactions has been driving research in this area for several decades.
Touber, Emile, Sandham, Neil D.
core   +1 more source

The impact of three-dimensional compression on supersonic boundary layers [PDF]

AIP Advances
By using vertically intersecting double wedges, the effect of three-dimensional compression on a supersonic boundary layer transition and turbulent characteristics is experimentally investigated by means of nanoparticle-based planar laser scattering and ...
Qiancheng Wang, Jinghao Wen, Yuxin Zhao, Yilong Zhao   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source